New PET tracer could sharpen cancer detection

NCT ID NCT05641896

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a new radioactive tracer called [18F]FAPI-74 for PET scans in people with gastrointestinal cancers, including liver, bile duct, stomach, pancreatic, and colorectal cancers. The goal was to see if the tracer can accurately detect cancer cells by comparing scan results with tissue samples. A total of 109 participants were enrolled, and the study has been completed.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

[18F]FAPI-74 (a radioactive tracer for PET imaging)

What this could lead to

If successful, this imaging method could help doctors more accurately detect and locate gastrointestinal cancers, potentially guiding better treatment decisions.

What could go wrong

This is a phase 2 study with a moderate number of participants. The imaging agent may not prove more effective than current methods, and results may not apply to all cancer types.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cholangiocarcinoma colorectal cancer colorectal neoplasm digestive system cancer digestive system neoplasm gastric cancer gastric neoplasm hepatocellular carcinoma pancreatic ductal adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • BAMF Health

    Grand Rapids, Michigan, 49503, United States

  • Massachusetts general hospital

    Boston, Massachusetts, 02114, United States

  • Mayo Clinic Rochester

    Rochester, Minnesota, 55902, United States

  • Memorial Sloan Kettering Cancer Center (MSKCC)

    New York, New York, 10065, United States

  • Northwell Health

    Lake Success, New York, 11042, United States

  • University of California Los Angeles (UCLA) Health

    Los Angeles, California, 90095, United States