Magnesium may shield against colon cancer in genetically prone individuals

NCT ID NCT01105169

First seen Feb 26, 2026 · Last updated Apr 30, 2026 · Updated 11 times

Summary

This study looked at whether taking magnesium supplements could reduce the risk of colorectal cancer in people with a specific genetic makeup. Researchers gave 250 participants either magnesium or a placebo for 12 weeks and measured changes in colon tissue markers linked to cancer development. The goal was to see if lowering the calcium-to-magnesium ratio in the diet could help prevent polyps, especially in those with a certain gene variant.

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Contacts and locations

Locations

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37203, United States

Conditions

Explore the condition pages connected to this study.