Immunonutrition before surgery may cut complications and preserve muscle in colorectal cancer patients

NCT ID NCT07653737

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial compares two types of oral nutritional supplements given to colorectal cancer patients before surgery. One group receives standard high-protein drinks, while the other gets immunonutrition drinks enriched with arginine, nucleotides, vitamin D, and omega-3 fatty acids. The goal is to see if the enriched supplements reduce post-surgical complications and help maintain muscle mass, as measured by CT scans. The study involves 56 adults scheduled for colorectal cancer surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Oral nutritional supplements with immunonutrition (arginine, nucleotides, vitamin D, omega-3 fatty acids)

What this could lead to

If it works, this could point toward a better way to prepare colorectal cancer patients for surgery, reducing complications and helping them maintain muscle strength.

What could go wrong

This is a small, early-stage study with only 56 participants, so results may not apply to everyone. The supplements may cause digestive discomfort or allergic reactions in some people.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal neoplasm Sarcopenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hospital Universitario Ramón y Cajal

    Madrid, Madrid, 28034, Spain