Exercise and creatine combo may restore strength in cancer survivors

NCT ID NCT06420726

First seen Jun 08, 2026 · Last updated Jun 23, 2026 · Updated 4 times

Summary

Many colorectal cancer survivors lose muscle mass and strength after chemotherapy. This study tested whether adding creatine supplements to a 10-week resistance training program could help. Twenty-seven survivors participated, comparing those who took creatine with those who only exercised. The goal was to see if this combination is feasible and acceptable, and whether it improves muscle strength, physical function, and quality of life.

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Contacts and locations

Locations

  • University of South Carolina

    Columbia, South Carolina, 29201, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

creatine monohydrate

What this could lead to

If this approach works, it could offer a simple way to help colorectal cancer survivors rebuild muscle strength and physical function after chemotherapy.

What could go wrong

This is a small pilot study with only 27 participants, so results may not apply to everyone. The combination of exercise and supplements may not provide additional benefit over exercise alone.

Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.