New drug targets wasting syndrome in cancer patients

NCT ID NCT05546476

First seen Jun 06, 2026 · Last updated Jun 17, 2026 · Updated 2 times

Summary

This study tested an investigational drug called ponsegromab in 187 adults with lung, pancreatic, or colorectal cancer who also had cachexia—a condition causing severe weight loss, loss of appetite, and fatigue. The goal was to see if ponsegromab could help patients gain weight and be more active compared to a placebo. The study was completed and used wearable sensors to track physical activity.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Aichi Cancer Center Hospital

    Nagoya, Nagoya, Aichi, 464-8681, Japan

  • Bacs-Kiskun Varmegyei Oktatokorhaz

    Kecskemét, Bács-Kiskun county, 6000, Hungary

  • Beverly Hills Cancer Center

    Beverly Hills, California, 90211, United States

  • Bozeman Health Deaconess Hospital

    Bozeman, Montana, 59715, United States

  • CARTI Cancer Center

    Little Rock, Arkansas, 72205, United States

  • CARTI Conway

    Conway, Arkansas, 72034, United States

  • CARTI North Little Rock

    North Little Rock, Arkansas, 72117, United States

  • CARTI Stuttgart

    Stuttgart, Arkansas, 72160, United States

  • CIUSSS- saguenay-Lac-Saint-Jean

    Chicoutimi, Quebec, G7H 5H6, Canada

  • Carta - Clinical Associates in Research Therapeutics of America, LLC

    San Antonio, Texas, 78212, United States

  • Centre intégré de santé et de services sociaux du Bas Saint-Laurent- Hôpital régional de Rimouski

    Rimouski, Quebec, G5L 5T1, Canada

  • Centrum Badań Klinicznych Jagiellońskie Centrum Innowacji sp. z o.o.

    Krakow, Lesser Poland Voivodeship, 30-348, Poland

  • Chang Gung Medical Foundation-Linkou Branch

    Taoyuan, 333, Taiwan

  • Changzhou No.2 People's Hospital

    Changzhou, Jiangsu, 213003, China

  • Chi Mei Hospital - Liouying Branch

    Tainan, Tainan, 73657, Taiwan

  • China Medical University Hospital

    Taichung, 404332, Taiwan

  • Complex Oncology Center - Burgas

    Burgas, 8000, Bulgaria

  • Complex Oncology Center - Ruse EOOD

    Rousse, 7002, Bulgaria

  • Complex Oncology Center - Shumen

    Shumen, 9700, Bulgaria

  • Complex Oncology Center - Vratsa

    Vratsa, 3000, Bulgaria

  • Emad Ibrahim,MD,INC.

    Redlands, California, 92373, United States

  • Fakultna nemocnica Trnava

    Trnava, 917 75, Slovakia

  • Fakultna nemocnica s poliklinikou F. D. Roosevelta Banska Bystrica

    Banská Bystrica, 975 17, Slovakia

  • Fakultna nemocnica s poliklinikou Nove Zamky

    Nové Zámky, 940 34, Slovakia

  • Fundación Instituto Valenciano de Oncología

    Valencia, Valenciana, Comunitat, 46009, Spain

  • Henan Cancer Hospital

    Zhengzhou, Henan, 450008, China

  • Hospital Son Llàtzer

    Palma, Illes Balears [islas Baleares], 07198, Spain

  • Hospital Universitari General de Catalunya

    Sant Cugat del Vallès, Barcelona [barcelona], 08915, Spain

  • Hospital Universitari i Politecnic La Fe

    Valencia, 46026, Spain

  • Hospital Universitario HM Sanchinarro

    Madrid, 28050, Spain

  • Hyogo Cancer Center

    Akashi, Hyōgo, 673-8558, Japan

  • IU Health Arnett Cancer Center

    Lafayette, Indiana, 47904, United States

  • Institut Català d'Oncologia - L'Hospitalet

    L'Hospitalet de Llobregat, Catalunya [cataluña], 08908, Spain

  • Jász-Nagykun-Szolnok Megyei Hetényi Géza Kórház

    Szolnok, Jász-Nagykun-Szolnok, 5004, Hungary

  • Kanagawa cancer center

    Yokohama, Kanagawa, 241-8515, Japan

  • Kaohsiung Medical University Chung-Ho Memorial Hospital

    Kaohsiung City, 807, Taiwan

  • MHAT for Women's Health Nadezhda

    Sofia, 1330, Bulgaria

  • Multiprofile Hospital for Active Treatment Serdika EOOD

    Sofia, 1303, Bulgaria

  • NZOZ "Vegamed"

    Katowice, 40-060, Poland

  • Narodny onkologicky ustav, II. Onkologicka klinika LFUK a NOU

    Bratislava, 833 10, Slovakia

  • National Cancer Center Hospital East

    Kashiwa, Chiba, 277-8577, Japan

  • National Cheng Kung University Hospital

    Tainan, 704, Taiwan

  • National Hospital Organization Shikoku Cancer Center

    Matsuyama, Ehime, 791-0280, Japan

  • Nemocnica na okraji mesta, n.o.

    Partizánske, 95801, Slovakia

  • Orange Hospital

    Orange, New South Wales, 2800, Australia

  • Oregon Health and Science University

    Portland, Oregon, 97239, United States

  • Oregon Health and Science University: Center for Health and Healing 1

    Portland, Oregon, 97239, United States

  • Oregon Health and Science University: Center for Health and Healing 2

    Portland, Oregon, 97239, United States

  • Országos Korányi Pulmonológiai Intézet

    Budapest, 1121, Hungary

  • Pacific Cancer Medical Center INC

    Anaheim, California, 92801, United States

  • Peking University First Hospital

    Beijing, Beijing Municipality, 100034, China

  • Pennington Biomedical Research Center

    Baton Rouge, Louisiana, 70808, United States

  • Peter MacCallum Cancer Centre

    Melbourne, Victoria, 3000, Australia

  • Princess Margaret Cancer Centre

    Toronto, Ontario, M5G 2M9, Canada

  • Providence Medical Foundation

    Santa Rosa, California, 95403, United States

  • Qilu Hospital of Shandong University

    Jinan, Shandong, 250012, China

  • Regionalny Szpital Specjalistyczny im. Dr. Wladyslawa Bieganskiego

    Grudziądz, 86-300, Poland

  • Semmelweis Egyetem

    Budapest, 1083, Hungary

  • Shanghai Changhai Hospital

    Shanghai, Shanghai Municipality, 200433, China

  • Shanxi Provincial Cancer Hospital

    Taiyuan, Shanxi, 030013, China

  • Shizuoka Cancer Center

    Nagaizumi-cho, Shizuoka, 411-8777, Japan

  • Sir Run Run Shaw Hospital of Zhejiang University School of Medicine

    Hangzhou, Zhejiang, 310016, China

  • Specialized Hospital for Active Treatment of Oncology - Haskovo

    Haskovo, 6300, Bulgaria

  • Specjalistyczna Praktyka Lekarska Slawomir Mandziuk

    Lublin, 20-093, Poland

  • St Vincent's Hospital Sydney

    Darlinghurst, New South Wales, 2010, Australia

  • Tandem Clinical Research

    Marrero, Louisiana, 70072, United States

  • The 2nd Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University

    Wenzhou, Zhejiang, 325035, China

  • The Cancer Institute Hospital of JFCR

    Tokyo, 135-8550, Japan

  • The First Affiliated Hospital of Nanchang University

    Nanchang, Jiangxi, 330006, China

  • The Ottawa Hospital - General Campus

    Ottawa, Ontario, K1H 8L6, Canada

  • The University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology

    Wuhan, Hubei, 430030, China

  • University Hospital,Kyoto Prefectural University of Medicine

    Kyoto, 602-8566, Japan

  • University Multiprofile Hospital for Active Treatment Sofiamed

    Sofia, 1797, Bulgaria

  • Univerzitna nemocnica Bratislava, Nemocnica Ruzinov

    Bratislava, 826 06, Slovakia

  • Virginia Mason Medical Center

    Seattle, Washington, 98101, United States

  • Wenatchee Valley Hospital

    Wenatchee, Washington, 98801, United States

  • Western Health-Sunshine & Footscray Hospitals

    St Albans, Victoria, 3021, Australia

Conditions

Explore the condition pages connected to this study.