Scientists hunt for biomarkers to personalize cancer therapy

NCT ID NCT00628368

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study analyzed tumor and blood samples from 160 people with esophageal or rectal cancer. Researchers looked for genetic markers in the EGFR signaling pathway that might predict how well a patient responds to chemoradiotherapy given before surgery. The goal is to better understand which patients benefit most from this treatment approach.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could help doctors predict which patients will respond well to chemoradiotherapy, leading to more personalized treatment plans.
What could go wrong
This is an observational, lab-based study, not a treatment trial. The findings may not translate into immediate clinical changes or benefit participants directly.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Centre Regional de Lutte Contre le Cancer - Centre Val d'Aurelle

    Montpellier, 34298, France

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Other studies related to the condition(s) this trial covers.