Biosimilar cancer drug CDP1 aims to match cetuximab in advanced tumors

NCT ID NCT03491709

First seen Jul 06, 2026 · Last updated Jul 07, 2026 · Updated 1 time

Summary

This study tests a new drug called CDP1, which is a biosimilar (a close copy) of the approved cancer drug cetuximab. The trial enrolls adults with advanced colorectal cancer or head and neck squamous cell carcinoma that has not responded to prior treatments. Researchers compare how the body processes CDP1 versus cetuximab and check for side effects. The goal is to see if CDP1 is a safe and similar alternative to cetuximab.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
CDP1 (anti-EGFR monoclonal antibody, similar to cetuximab)
What this could lead to
If CDP1 works as well as cetuximab, it could offer a more affordable treatment option for advanced colorectal and head and neck cancers.
What could go wrong
This is a small, early-phase study focused on safety and drug levels, not yet on effectiveness. The drug may not prove as effective or safe as cetuximab in larger trials.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Shanghai East Hospital Phase 1 Clinical Trial Center

    Shanghai, Shanghai Municipality, 201203, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.