Pilot study pits cologuard against FIT for colon cancer screening in younger adults
NCT ID NCT06173375
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study compared two stool-based tests—Cologuard and the fecal immunochemical test (FIT)—for colorectal cancer screening in adults aged 45-49. Researchers mailed the tests to eligible participants and tracked how many completed screening, had abnormal results, and followed up with a colonoscopy. The study involved only 12 people and aimed to see which test works better for this age group.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Cologuard (multi-target stool DNA test) and Fecal Immunochemical Test (FIT)
What this could lead to
If successful, this could help determine which stool-based screening method is more effective for colorectal cancer detection in younger adults.
What could go wrong
This is a very small pilot study with only 12 participants, so results may not apply to larger populations. It does not test new treatments or cures.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University of California San Diego
La Jolla, California, 92126, United States