Heartburn drug may shield cancer patients from nerve pain
NCT ID NCT05680870
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tested whether omeprazole, a common heartburn medication, could prevent nerve damage caused by oxaliplatin chemotherapy in 46 adults with colorectal or pancreatic cancer. Participants took omeprazole before and during chemotherapy cycles. The goal was to see if it reduced acute and chronic peripheral neuropathy symptoms.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- omeprazole
- What this could lead to
- If it works, this could offer a simple, low-cost way to prevent painful nerve damage caused by oxaliplatin chemotherapy.
- What could go wrong
- This is a small, completed phase 3 trial with only 46 participants. Results may not apply to all patients, and omeprazole's protective effect is not yet proven.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Tanta university
Tanta, Egypt
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