New drug combo shows promise for Hard-to-Treat colon cancer
NCT ID NCT03712943
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase study tested a combination of two drugs, regorafenib and nivolumab, in 52 people with advanced colorectal cancer that had stopped responding to other treatments. The goal was to find the safest dose and see if the combination could help control the cancer. The study focused on patients whose tumors have a specific feature called mismatch repair proficiency, which often makes them harder to treat.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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Locations
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H. Lee Moffitt Cancer Center and Research Institute
Tampa, Florida, 33612, United States