New drug combo shows promise for Hard-to-Treat colon cancer

This early-phase study tested a combination of two drugs, regorafenib and nivolumab, in 52 people with advanced colorectal cancer that had stopped responding to other treatments. The goal was to find the safest dose and see if the combination could help control the cancer. The study focused on patients whose tumors have a specific feature called mismatch repair proficiency, which often makes them harder to treat.