Could a Two-Drug pain block ease recovery after colon cancer surgery?

NCT ID NCT06370949

First seen Jul 02, 2026 · Last updated Jul 02, 2026

Summary

This trial compares two approaches to a nerve block (TAP block) for pain after colorectal cancer surgery. One group receives the standard numbing drug bupivacaine, while the other gets bupivacaine plus dexmedetomidine, a drug that may extend pain relief. The study measures pain scores using a 0–10 scale in the hours after surgery. About 84 adults with colorectal cancer scheduled for surgery are taking part.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

bupivacaine and dexmedetomidine

What this could lead to

If it works, this could offer better pain relief after colorectal cancer surgery, reducing the need for strong painkillers.

What could go wrong

This is a small, early-stage trial. The added drug may not improve pain control and could cause side effects like low blood pressure or drowsiness.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

More trials for these conditions

Other studies related to the condition(s) this trial covers.

Contacts and locations

Locations

  • Turkey Dr.Abdurrahman Yurtaslan Ankara Oncology Train and Research Hospital

    Ankara, Cankaya, 06110, Turkey (Türkiye)