Could a Two-Drug pain block ease recovery after colon cancer surgery?

NCT ID NCT06370949

Completed Symptom relief Sponsor: Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital Source: ClinicalTrials.gov ↗

First seen Jul 02, 2026 · Last updated Jul 02, 2026

Summary

This trial compares two approaches to a nerve block (TAP block) for pain after colorectal cancer surgery. One group receives the standard numbing drug bupivacaine, while the other gets bupivacaine plus dexmedetomidine, a drug that may extend pain relief. The study measures pain scores using a 0–10 scale in the hours after surgery. About 84 adults with colorectal cancer scheduled for surgery are taking part.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: bupivacaine and dexmedetomidine
What this could lead to: If it works, this could offer better pain relief after colorectal cancer surgery, reducing the need for strong painkillers.
What could go wrong: This is a small, early-stage trial. The added drug may not improve pain control and could cause side effects like low blood pressure or drowsiness.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COLORECTAL CANCER COLORECTAL NEOPLASMS

Contacts and locations

Locations

Turkey Dr.Abdurrahman Yurtaslan Ankara Oncology Train and Research Hospital

Ankara, Cankaya, 06110, Turkey (Türkiye)

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