Simple gel may prevent chemo side effect
NCT ID NCT07177560
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study looked at whether applying a topical diclofenac gel to the hands and feet could prevent or delay hand-foot syndrome in patients with colorectal or gastric cancer taking capecitabine. About 150 patients were observed at two cancer centers in Turkey. The goal was to see if the gel reduces the number of patients who develop moderate to severe skin reactions.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
topical diclofenac gel
What this could lead to
If it works, this could offer a simple, low-cost way to prevent a painful side effect of chemotherapy, helping patients stay on treatment.
What could go wrong
This is an observational study, not a randomized trial, so results may be less reliable. The gel may not prevent hand-foot syndrome, and some patients may still need dose reductions.
Disclaimer
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the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Ankara Etlik City Hospital
Ankara, Turkey (Türkiye)
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Gazi University
Ankara, Turkey (Türkiye)