Common supplement may shield cancer patients from nerve pain

NCT ID NCT07391163

Completed Symptom relief Sponsor: Tanta University Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether taking N-Acetylcysteine before chemotherapy could reduce nerve damage in colorectal cancer patients receiving oxaliplatin. 46 participants received either N-Acetylcysteine or a placebo before each chemo session. The goal was to see if the supplement could lower the risk and severity of tingling, numbness, and pain in hands and feet.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: N-Acetylcysteine
What this could lead to: If it works, this could point toward a way to prevent or reduce nerve pain and numbness caused by chemotherapy, improving quality of life for cancer patients.
What could go wrong: This is a small, completed trial with only 46 participants, so results may not apply to everyone. The protective effect may be modest or not statistically significant.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for COLORECTAL CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal neoplasm peripheral nervous system disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COLORECTAL CANCER

Contacts and locations

Locations

Tanta University - Faculty of Medicine ,oncology department, Tanta university hospital.

Tanta, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.