Common supplement may shield cancer patients from nerve pain

NCT ID NCT07391163

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether taking N-Acetylcysteine before chemotherapy could reduce nerve damage in colorectal cancer patients receiving oxaliplatin. 46 participants received either N-Acetylcysteine or a placebo before each chemo session. The goal was to see if the supplement could lower the risk and severity of tingling, numbness, and pain in hands and feet.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

N-Acetylcysteine

What this could lead to

If it works, this could point toward a way to prevent or reduce nerve pain and numbness caused by chemotherapy, improving quality of life for cancer patients.

What could go wrong

This is a small, completed trial with only 46 participants, so results may not apply to everyone. The protective effect may be modest or not statistically significant.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal neoplasm peripheral nervous system disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Tanta University - Faculty of Medicine ,oncology department, Tanta university hospital.

    Tanta, Egypt