Cancer

This phase 1 trial is testing an experimental therapeutic cancer vaccine called AST-021p in people with advanced solid tumors that no longer respond to standard treatments. The goal is to see if the vaccine is safe and can trigger an immune response against the cancer. Participan…

This study tested whether a personalized vaccine could be safely made and given to 25 adults with advanced cancers that cannot be cured. The vaccine was custom-made for each person. The main goal was to check for side effects and see if the approach is feasible.

This study tested two treatments for people with advanced cancer who cannot have standard therapy. One group took a low-dose chemotherapy pill (cyclophosphamide) daily, and the other took a hormone pill (megestrol). The goal was to see which treatment could slow cancer growth for…

This early-phase trial tested two cancer drugs—imatinib mesylate and cyclophosphamide—given daily by mouth to 26 people with rare, advanced tumors that had no standard treatment. The main goal was to find the safest dose of imatinib when combined with a fixed dose of cyclophospha…

This phase 1 trial is testing whether a diet that severely limits arginine—an amino acid some tumors depend on—is safe and might help control solid tumors. About 25 adults with solid tumors will follow a specially designed low-arginine liquid diet for two 3-week cycles while cont…

This early-stage trial tests an experimental drug called SG2918 in 17 people with advanced cancers that no longer respond to standard treatments. The main goal is to check safety and find the right dose, not yet to prove it works. Participants receive the drug by IV every three w…

This study tested three flavors of Supportan® drink (Tropical Fruits, Cappuccino, and Pineapple-Coconut) in 123 cancer patients undergoing chemotherapy, radiotherapy, immunotherapy, or targeted therapy. Patients drank two bottles daily for four weeks alongside their normal diet. …

This trial tests an experimental drug called FLX475, given alone or with the immunotherapy pembrolizumab, in people with advanced cancers that have not responded to standard treatments. The study aims to find the safest dose and to see whether the combination can shrink tumors. P…

This study looks at whether eating a high-fiber diet (over 21 grams per day) can change gut bacteria and improve the immune system's ability to fight solid tumors like colorectal cancer. About 25 adults with solid tumors will follow this diet to see if it is safe and helps with t…

This trial tests an experimental drug called SNS-101, which targets a protein called VISTA that may help tumors evade the immune system. Researchers give SNS-101 alone or with another immunotherapy, cemiplimab, to adults with advanced solid tumors that have not responded to stand…

This trial tests whether combining cabozantinib, a drug that blocks tumor blood vessel growth, with avelumab, an immunotherapy that boosts the immune system, can control advanced neuroendocrine neoplasia G3 (NEN G3). The study enrolls adults whose cancer has progressed after at l…

This trial tests a structured diet and exercise program for overweight Chinese cancer survivors. The program, led by a dietitian and a cancer exercise specialist, teaches weight loss strategies, healthy eating, and physical activity. Researchers want to see if the program is prac…

This early-phase trial tested a combination of two drugs, vandetanib and everolimus, in 151 people with advanced or metastatic cancer that had stopped responding to standard treatments. The goal was to find the safest dose and see if the combination could slow or stop cancer grow…

This early-stage trial is testing whether combining two chemotherapy drugs, temozolomide and topotecan, is safe and tolerable for children and adolescents with malignant tumors that have returned or not responded to standard treatments. The study aims to find the highest safe dos…

This early-phase study tested an experimental drug called COM902, alone or with other drugs, in 94 people with advanced cancers like ovarian, lung, and colon cancer. The main goal was to check safety and find the right dose. Researchers also looked for early signs that the drug m…

This trial tests whether giving the sedative dexmedetomidine during and after reconstructive microsurgery can help transplanted tissue (flaps) survive better in cancer patients. The study will compare flap health at 48 hours after surgery in patients receiving dexmedetomidine ver…

This phase 3 trial tests whether the immunotherapy drug nivolumab can delay cancer recurrence in people who have had surgery for high-risk invasive urothelial cancer (a type of bladder cancer). About 709 participants received either nivolumab or a placebo after surgery. The main …

This phase 2 trial is testing whether the chemotherapy drug temozolomide can shrink tumors in people with a rare type of gastrointestinal stromal tumor (GIST) that has a mutation in the SDH gene. Standard GIST treatments do not work for this subtype. Participants take temozolomid…

This trial tests whether starting oral feeding within 24 hours after ileostomy reversal surgery is safer than waiting 48 to 72 hours for bowel function to return. The main question is whether early feeding reduces the chance of anastomotic leakage, a serious complication where in…

This trial compares two common methods for placing a totally implantable vascular access device (TIVAD), a port used for chemotherapy and other treatments in cancer patients. Researchers are randomly assigning patients to have the port inserted via either the internal jugular vei…

This completed phase I/IIb trial tested a personalized vaccine made from each patient's unique tumor mutations. Eight adults with advanced solid tumors or high recurrence risk received the vaccine alongside an immune booster and later checkpoint inhibitors. The goal was to see if…

This phase 3 trial tests whether a web-based physical activity program, including a wearable tracker and interactive app, can improve fitness and long-term health in children and adolescents who have completed cancer treatment. Participants are randomly assigned to receive either…

This study tests a support program that brings together oncologists, pharmacists, doctors, and nurses to help cancer patients take their oral medications as prescribed. The goal is to improve treatment effectiveness and patient safety by ensuring better communication and follow-u…

This early-stage trial tests a treatment called Anti-CEA CAR-T, which uses a patient's own immune cells modified to recognize and attack cancer cells that carry a protein called CEA. The study enrolls about 110 adults with advanced colorectal, gastric, or other solid tumors that …

This early-phase trial tests an experimental drug called JS006, either by itself or combined with another drug (toripalimab), in people with advanced tumors who have no standard treatment options left. The goal is to see if the combination is safe and tolerable, and to find the b…

This early-stage trial tests a new type of cell therapy called CEA-targeted CAR-T for people with advanced colorectal, esophageal, stomach, or pancreatic cancers that have stopped responding to standard treatments. The therapy involves taking a patient's own immune cells, enginee…

This early-phase study tests a new oral drug called TT125-802 in 50 adults with advanced solid tumors (like lung cancer) that have not responded to standard treatments. The main goals are to check the drug's safety, find the right dose, and see if it can shrink tumors. It is a fi…

This early-stage trial is testing a combination of two lab-made antibodies in people with advanced solid tumors that have not responded to standard treatments. One antibody (LDP) aims to reactivate the immune system against cancer, while the other (CDP1) blocks a growth signal on…

This early-stage trial tests a new drug called LDP, an antibody that blocks PD-L1, a protein cancers use to hide from the immune system. The study enrolls adults with advanced malignant tumors who have exhausted standard treatments. Researchers are evaluating the drug's safety, t…

This study tests whether combining two targeted drugs, avutometinib and adagrasib, can shrink tumors in people with advanced non-small cell lung cancer that has a specific genetic change called KRAS G12C. Participants must have already tried a KRAS G12C inhibitor and seen their c…

This study tested whether adding Naderin (sodium nucleinate) to standard treatment could reduce complications in 75 patients with cancer, tuberculosis, or hepatitis C. The main group received Naderin plus standard therapy, while the control group received standard therapy alone. …

This early-phase trial tested an experimental drug called KVA12123, given alone or with the immunotherapy Keytruda, in 40 adults with advanced solid tumors (like lung, breast, or colon cancer) that had stopped responding to standard treatments. The main goals were to check safety…

This study tests whether adding virtual reality video games to standard breathing and exercise therapy helps children aged 5 to 18 recover better after a stem cell transplant. Participants do 24 supervised sessions over 8 weeks, either with standard rehab alone or standard rehab …

This study tested a drug called PF-06801591 in 155 people with advanced solid tumors or non-small-cell lung cancer. The drug works by blocking a protein that stops the immune system from attacking cancer cells. The goal was to check safety, how the drug moves through the body, an…

This early study tested whether a sterile bacterial chemical called lipopolysaccharide (LPS) can be safely injected into abdominal tumors during laparoscopic surgery. Twelve adults with advanced digestive tract tumors received one injection into a tumor, and researchers checked f…

This study tested two experimental drugs (AK104 and AK117) together, sometimes with chemotherapy, in 128 people with advanced solid tumors. The goal was to see if the combination is safe and can shrink tumors. It focused on patients with stomach, esophageal, or other advanced can…

This early-phase study tested a personalized cancer vaccine (RO7198457) in 273 patients with advanced solid tumors like melanoma, lung, and breast cancer. The vaccine was given alone or with an immunotherapy drug (atezolizumab) to see if it was safe and how the body responded. Th…

This study looked at the long-term safety of several cancer drugs, including tislelizumab and pamiparib, in 404 people with advanced cancers. Participants had already been in an earlier trial of these drugs. The goal was to track serious side effects and see if patients could kee…

This early-stage trial tested an experimental drug called LVGN6051, which activates immune cells by targeting CD137, both alone and combined with the approved immunotherapy Keytruda. The study involved 105 adults with advanced or metastatic cancers that had spread. The main goal …

This early-stage study tested a new drug called LVGN7409, which boosts the immune system to fight cancer. It was given alone or with other immune-boosting drugs to 66 adults with advanced cancers that had stopped responding to standard treatments. The main goal was to find the sa…

This early-phase trial tested an experimental drug called NEV801 in 78 adults with advanced solid tumors that had stopped responding to standard treatments. The drug was given by IV in increasing doses to find the safest dose and to see if it had any anti-cancer effects. The stud…

This study tested whether giving older cancer patients (70+) personalized physical activity advice helps them maintain physical function and independence during curative cancer treatment. Over 300 participants were randomly assigned to either a standard exercise guide or a progra…

This study tested a new drug called LBL-033 in 26 adults with advanced malignant tumors that had not responded to other treatments. The main goals were to find a safe dose and check for serious side effects. Researchers also looked at how the drug moves through the body and wheth…

This early-phase study tested a daily combination of two oral drugs, axitinib and everolimus, in 19 people with advanced solid tumors, particularly kidney cancer. The main goal was to find the safest dose by monitoring side effects in the first month. Researchers also tracked how…

This study tested the drug sunitinib (Sutent) in 71 people with advanced thyroid cancer that had spread or could not be removed by surgery. The goal was to see if the drug could shrink tumors when standard treatments like radioactive iodine no longer work. Participants took sunit…

This early-phase study tested a new drug called CCT3833 in 31 adults with advanced solid tumours, including melanoma. The main goal was to find a safe dose and check for side effects. Researchers measured how the drug moves through the body and looked for the best dose to use in …

This phase I trial tested a special type of radiation called hypofractionated radiosurgery for people with large brain metastases (tumors that spread from other cancers). The goal was to find the safest and most effective dose while limiting damage to healthy brain tissue. Twenty…

This study tested whether adding the drug axitinib to standard sandostatin LAR therapy could slow tumor growth in 256 people with advanced neuroendocrine tumors (G1-G2) that started outside the pancreas. Participants received either the combination or sandostatin plus a placebo. …

This phase 2 trial tested the drug samotolisib in 18 children and young adults with advanced solid tumors, non-Hodgkin lymphoma, or histiocytic disorders that had spread, returned, or stopped responding to treatment. Only patients whose tumors had specific mutations in the TSC or…

This phase 2 trial tested whether combining two immunotherapy drugs, nivolumab and relatlimab, can help people with advanced or metastatic soft-tissue sarcoma. The study enrolled 68 adults whose tumors had a specific immune structure. Researchers measured how many patients had th…

This early-phase study tested a new drug called TQB2210 in 16 people with advanced cancers that had not responded to other treatments. The drug is a lab-made antibody that targets a specific protein (FGFR2b) on cancer cells to block their growth. The main goals were to find a saf…

This study tested a drug called tazemetostat in 20 children whose cancers had come back or weren't responding to treatment. The children had specific gene changes (EZH2, SMARCB1, or SMARCA4) in their tumors. The goal was to see if the drug could shrink or slow the growth of these…

This early-phase trial tested a new type of radiation called carbon ion therapy for people with locally advanced pancreatic cancer that cannot be removed by surgery. Fourteen participants received increasing doses of carbon ion radiation along with chemotherapy. The main goal was…

This study looked at whether eating a whole-food, plant-based diet for 8 weeks could lower markers of cancer and inflammation in firefighters. 121 active firefighters participated. Researchers measured changes in blood markers like IL-6 and C-reactive protein to see if the diet m…

This phase II trial tested whether a newer antibiotic combination (imipenem-relebactam) works better than standard antibiotics for treating fever caused by low white blood cell counts in cancer patients. About 100 adults with cancer or who had a stem cell transplant took part. Th…

This study looked at whether adding a special type of physiotherapy after lymphovenous anastomosis surgery helps people with lymphedema more than physiotherapy alone. Lymphedema is a condition where fluid builds up and causes swelling, often after cancer treatment. The study invo…

This study tested a new drug called STRO-002 in 19 Chinese adults with advanced ovarian, endometrial, or other solid tumors that had not responded to prior treatments. STRO-002 is an antibody-drug conjugate, meaning it combines a targeted antibody with a chemotherapy drug to deli…

This early-phase trial tested whether combining the experimental drug relatlimab with other immunotherapies (nivolumab plus either BMS-986205 or ipilimumab) is safe and can shrink tumors in people with advanced solid cancers. A total of 229 participants with various incurable, ad…

This study tested a drug called palbociclib in 23 children and young adults (ages 1–21) whose cancers had come back or didn't respond to treatment. The drug works by blocking proteins that help cancer cells grow. The goal was to see if it could shrink tumors or slow the disease i…

This completed trial tested an online Tai Chi program to help cancer survivors stop smoking. Sixty-eight participants practiced slow movements and breathing exercises over 8 weeks, with their progress tracked via carbon monoxide tests and surveys. The goal was to see if this gent…

This study tested a weight management program for young adult cancer survivors (ages 18-39) who have obesity and are within 5 years of finishing cancer treatment. The program combined healthy eating, physical activity, and symptom management to help reduce cardiovascular disease …

This study checked if a generic version of the cancer drug trifluridine/tipiracil works the same as the brand-name drug Lonsurf in 76 patients with solid tumors. Participants took the drug under fasting and fed conditions to compare how the body absorbs it. The goal was to show t…

This early-stage study tested an experimental drug called JCXH-211, which is injected directly into tumors. It involved 19 adults with advanced solid tumors that had not responded to standard treatments. The main goals were to check safety and find the right dose, while also watc…

This early-stage study tested a new drug called DF6215, alone or with another drug (pembrolizumab), in 35 adults with advanced solid tumors that could not be removed by surgery or had spread. The main goals were to find the safest dose and check for side effects. The study is com…

This early-phase study tested a combination of two chemotherapy drugs—weekly paclitaxel given through a vein and daily oral cyclophosphamide—in 28 adults with advanced cancer who had no other treatment options. The goal was to find the safest dose of paclitaxel when used with a f…

This early-phase study tested a new drug called HRS7415 in 38 people with advanced cancers that had spread. The main goals were to check safety, find the right dose, and see if the drug could help control the disease. Researchers monitored side effects and measured drug levels in…

This study tested a new way to give radiation to men with intermediate-risk prostate cancer. After standard radiation to the prostate and nearby glands, a precise, high-dose boost was added to the tumor. The goal was to improve cancer control while keeping side effects on the bla…

This phase 2 trial tested whether taking iohexol by mouth can treat chylous ascites, a leak of lymphatic fluid that can happen after abdominal or pelvic cancer surgery. The study enrolled 42 patients who developed this condition after surgery. The goal was to see if oral iohexol …

This study tested a combination of two experimental drugs, AK112 and AK117, with or without chemotherapy, in 154 people with advanced solid tumors. The goal was to see if the combo could shrink tumors and control the disease. The trial has finished, and researchers are now lookin…

This early-phase trial tested an experimental cell therapy called INKmune in 12 men with advanced prostate cancer that no longer responds to hormone therapy. The goal was to find the safest and most effective dose by measuring immune cell activity, PSA levels, and tumor changes. …

This phase II trial tested the drug infigratinib in 17 adults with advanced or metastatic solid tumors that have specific FGFR gene mutations. The drug works by blocking overactive FGFR proteins that help cancer grow. The study measured how many patients' tumors shrank or stabili…

This study tested an experimental drug (BMS-986253) combined with standard immunotherapy drugs (nivolumab with or without ipilimumab) in 281 people with advanced cancers like melanoma. The main goals were to check safety and see if tumors shrank. This is a disease-control approac…

This study looked at whether reducing the use of strong, broad-spectrum antibiotics in cancer patients with sepsis or septic shock is as safe as continuing them. The goal is to lower the risk of creating drug-resistant bacteria. Researchers compared a de-escalation strategy to st…

This phase 3 trial tested whether adding immunotherapy drugs (nivolumab and ipilimumab) to standard chemotherapy helps people with advanced esophageal cancer live longer or keep their cancer from growing. About 970 participants with inoperable or metastatic esophageal squamous ce…

This study tested a program called CareConnect that uses automated phone calls to help cancer patients stop smoking. About 400 cancer patients who smoked took part. The program gave them educational messages and connected them to resources like quitlines or websites. The goal was…

This completed phase II study tested a combination of two drugs—tadalafil (Cialis) and pembrolizumab (Keytruda)—in 7 adults with advanced head and neck cancer that had spread or come back. The goal was to see if the combination was safe and could help control the disease. Because…

This study tested a new drug called RP-6306 in 28 people with advanced cancer that could not be cured. The goal was to see if adding RP-6306 to standard treatment helps shrink tumors and is safe. Researchers also looked for specific biomarkers to see if some patients respond bett…

This study followed 22 cancer patients who were already taking bintrafusp alfa in earlier trials, to see how safe it is over the long term and how long they live. Participants continued receiving the drug until it was no longer helping or became available commercially. The main g…

This early-phase trial tested a new drug called LBL-019, given alone or with another immunotherapy, in 26 adults with advanced cancers that no longer responded to standard treatments. The main goal was to check safety and find the right dose. Researchers also looked at whether th…

This early-stage trial tested an experimental drug called CyPep-1, injected directly into tumors, either alone or with the immunotherapy pembrolizumab. The study involved 60 adults with advanced solid cancers that had stopped responding to standard treatments. The main goals were…

This early-phase trial tested a new oral drug called ART4215 in 93 people with advanced or metastatic solid tumors, including breast cancer. The main goals were to find a safe dose and check for side effects when given alone or with other cancer drugs (talazoparib or niraparib). …

This early-phase study tested an experimental drug called BMS-986288, both by itself and combined with the immunotherapy nivolumab (Opdivo), in 219 people with advanced solid tumors that had worsened after standard treatments. The main goal was to check safety and tolerability, a…

This study tested a new drug called XNW5004 in 120 people with advanced tumors or lymphoma that had come back or stopped responding to standard treatments. The goal was to check the drug's safety, find the right dose, and see if it helps shrink tumors. The drug is taken as a tabl…

This early-stage trial tested a new drug called MRX-2843 in 42 adults with advanced solid tumors that had spread or come back after other treatments. The main goal was to check safety and find the right dose. Researchers monitored side effects and how the drug moved through the b…

This early-phase study tested a new drug called RC108-ADC in 67 people with advanced solid tumors that have a specific protein (c-Met). The drug is designed to deliver a toxin directly to cancer cells. The main goals were to check safety and find the best dose. Researchers also l…

This early-phase study tested an experimental oral drug called Q702 in 51 adults with advanced solid tumors that had stopped responding to standard treatments. The main goals were to find a safe dose and check for side effects, while also looking at whether the drug could shrink …

This study tested a new drug called RP903 in 69 people with advanced solid tumors (like ovarian, breast, or cervical cancer) who had run out of standard options. The main goals were to check safety, find the best dose, and see if the drug shrinks tumors. It is an early-phase tria…

This study tested a combination of two drugs, lenvatinib and eribulin, in 30 people with advanced soft tissue sarcomas (liposarcoma or leiomyosarcoma) that could not be removed by surgery or had spread. The goal was to see if the combo could shrink tumors or slow their growth. Th…

This pilot study tested whether a structured exercise program is feasible for young cancer survivors (ages 18-45) who have mild heart dysfunction after cancer treatment. The program, called CORE, is like cardiac rehab and aims to improve heart health, fitness, and quality of life…

This large study looked at whether taking daily vitamin D or fish oil supplements could lower the risk of developing autoimmune diseases (like rheumatoid arthritis), reduce signs of inflammation in the blood, and ease chronic knee pain. Over 25,000 adults without prior cancer or …

This Phase 2 trial tested whether adding the immunotherapy drug durvalumab to standard chemoradiation (FOLFOX and radiation) helps patients with unresectable esophageal cancer. 112 patients were randomly assigned to receive either chemoradiation alone or chemoradiation plus durva…

This study tested whether the immunotherapy drug nivolumab can help prevent esophageal cancer from coming back after surgery. About 794 people who had surgery for stage II or III cancer of the esophagus or gastroesophageal junction received either nivolumab or a placebo. The main…

This study tested a smartphone app to help young adult cancer survivors (ages 18-39) lose weight. The app tracked diet and activity as part of a behavioral weight loss program. The goal was to see if this approach was practical and well-liked by participants. The study involved 6…

This early-phase trial tested a new drug, Karonudib, in 63 people with advanced solid tumors that had not responded to standard treatments. The main goal was to check the drug's safety and find the best dose. Researchers also looked at how the drug moves through the body and any …

This early-phase trial tested a new drug called PTX-100 in 25 people with advanced cancers like multiple myeloma, lymphoma, and certain solid tumors. The goal was to find safe doses and understand how the drug behaves in the body. Participants received the drug by IV for five day…

This study tested a quick finger-prick blood test to see if cancer patients had been infected with COVID-19 in the past. Researchers enrolled 214 adults being treated for cancer. The goal was to find out how many had antibodies, including those without symptoms, to help clinics k…

This study tested a handheld device that uses a single wave to measure how well the heart pumps blood and how stiff the arteries are. Researchers compared it to standard echocardiography in 159 cancer patients. The goal was to see if the device could also help identify patients a…

This completed study tested whether a special type of MRI called dynamic susceptibility contrast (DSC) perfusion MRI can accurately tell the difference between radiation-induced brain damage and tumor regrowth in people whose cancer has spread to the brain. Eight patients who had…

This study tested new adhesive sensors that stick to the skin to see if they can detect early signs of lymphedema, a painful arm swelling that can happen after cancer treatment. Researchers compared readings from 76 people with and without lymphedema. The goal is to create a simp…

This study tested a special PET scan tracer called FLT in 50 adults with brain tumors (gliomas or metastases). The goal was to see if FLT-PET can measure how fast tumor cells are growing, which could help doctors diagnose and predict tumor behavior better than current scans like …

This study tested small wearable sensors to see if they can accurately measure lymphedema, a condition where fluid builds up and causes swelling, often after cancer treatment. Thirty adults with arm lymphedema wore the sensors during one visit, and researchers compared the readin…

This study tested whether a simple checklist and blood test (the YEARS algorithm) can safely rule out pulmonary embolism (a blood clot in the lungs) in people with active cancer, compared to the standard approach of doing a CT scan on everyone. About 700 cancer patients with susp…

This early study tested a new radioactive tracer called 18F-FDS in 16 people with suspected bacterial or fungal infections. The tracer is designed to light up infection sites on PET/CT scans, helping doctors see exactly where an infection is. The goal was to check how the tracer …

This early study tested whether a special PET scan using a radioactive form of vitamin B9 (11C-PABA) can help doctors see infections deep inside the body. Researchers scanned 13 healthy people and patients with known or suspected infections. The goal was to see if this method can…

This trial tests whether adding peer health coaching to a standard prevention visit helps women aged 40-68 achieve more cancer screening and healthy lifestyle goals. Participants receive a one-on-one session with a trained prevention practitioner to set health goals, and some are…

This trial tests a cancer prevention program delivered by trained Chinese American community health workers to Chinese American adults in Texas. The program uses family health history to provide personalized education on breast, colorectal, gastric, liver, and lung cancers, along…

This trial tests whether motivational interviewing—a type of counseling that helps people find their own motivation to change—can help women overcome procrastination and get screened for cervical cancer. The study will include women aged 30-65 who have never had a Pap smear. Half…

This study follows people at high risk for diabetes who previously took part in a program testing intensive lifestyle changes or the drug metformin. The goal is to see if these approaches can prevent or delay diabetes and reduce long-term health problems like heart disease and ca…

This large study tested whether taking daily cocoa extract (a source of flavanols) or a standard multivitamin could lower the risk of heart disease and cancer in over 21,000 older adults. Participants took the supplements or placebos for several years, and researchers tracked hea…

This phase 3 trial tested whether a biologic called IMM-101 could reduce severe respiratory infections, including COVID-19, in cancer patients at higher risk. 195 participants either received three doses of IMM-101 or were simply observed. The goal was to see if the treatment cou…

This study tested whether ketoconazole, an antifungal drug, can reduce the skin rash caused by EGFR inhibitor cancer therapy. 58 participants with ongoing rash were given either ketoconazole or a placebo. The main goal was to see if the drug improved rash symptoms and quality of …

Researchers test a 10-week lifestyle program for people who have finished cancer treatment. The program combines structured exercise, nutrition counseling, and behavioral therapy. They compare it with a waitlist group to see how it affects cardiorespiratory fitness and body weigh…

This study is testing a mobile health app designed to help cancer survivors manage pain and other symptoms after treatment. Twenty-five survivors who have finished cancer treatment but still have pain will use the app for one week, receiving helpful messages and completing daily …

This study tests a pre-surgical toolkit (OPTI-Surg) designed to help older cancer patients recover more quickly after major surgery. The toolkit provides recommendations before surgery to improve physical function and reduce complications. About 325 participants with various canc…

This completed Phase 2 trial tested whether formal hypnosis, alongside standard care, could reduce anxiety and pain in 68 cancer patients undergoing brachytherapy. Patients received either standard care with Kalinox or standard care plus formal hypnosis. The study measured anxiet…

This study tested an experimental oral drug called Trichomylin® in 11 adults with advanced cancer who had moderate to severe pain despite taking strong opioids. The goal was to see if the drug is safe and can provide additional pain relief. Participants took the drug twice daily,…

This study tests an internet-based self-help program called eConquerFear-HK for Chinese cancer survivors who have mild to moderate fear of their cancer coming back. About 48 people who finished treatment for early-stage breast or colorectal cancer will try the program. The goal i…

This study tests a program that helps caregivers of teens and young adults (ages 15-26) with cancer find resources for financial and social needs. About 60 caregiver-patient pairs will take part. The goal is to see if this support reduces stress and improves well-being.

This trial tests whether wearing a grounding patch at night improves sleep quality in cancer patients who have insomnia while in the hospital. The patch is a hydrogel sticker on the forehead, connected by a cord to a true earth connection, which may lower the body's electrical vo…

This trial tests whether an AI emotional companion app can improve depression, anxiety, and demoralization in adults with advanced cancer. Participants use a mobile app where a virtual character holds conversations, reads emotional cues, and offers a link to a human hotline if di…

This trial tests whether art therapy can reduce physical and psychological symptoms in cancer patients receiving chemotherapy or immunotherapy. Over six treatment sessions, participants engage in artistic activities like painting, drawing, or clay work, guided by an art therapist…

This trial tests whether heated traditional Chinese medicine plasters can help cancer patients recover from chemotherapy-induced anemia and low blood cell counts. Participants apply the plaster to a specific point on the navel for one hour daily over two weeks. Researchers compar…

This study tests whether adding olanzapine to standard anti-nausea medicines can better control vomiting in children receiving strong chemotherapy. About 200 children will be randomly assigned to get either olanzapine or a placebo. The goal is to see if olanzapine helps more kids…

This study looked at whether laughter yoga could help cancer patients going through chemotherapy. 55 patients were split into two groups: one did weekly 40-minute laughter yoga sessions for four weeks, while the other received standard care. After four weeks, the laughter yoga gr…

This trial tests whether the Benson Relaxation Technique, a simple 15-minute guided relaxation exercise, can reduce pain, insomnia, nausea, vomiting, and retching in adults with cancer who are admitted to intensive care. Participants will practice the technique, which involves si…

This study tested a program to help cancer survivors quit smoking and manage pain. Nineteen survivors received counseling and the medication varenicline (Chantix). The goal was to see if the program was practical and helpful, not yet to prove it works.

This study tests whether a conversation game called 'Hello' can help people with cancer and their loved ones discuss advance care planning—decisions about future medical care. Participants will play either the Hello game or a similar conversation game, complete questionnaires, an…

This study tested whether one dose of radiation works as well as two doses for reducing pain from cancer that has spread to the bones. 102 adults with painful bone metastases took part. The goal was to see if a single treatment could provide similar pain relief and reduce the nee…

This trial tests whether a combined nerve block can provide better pain relief than standard local anesthesia for cancer patients undergoing chemoport implantation. The study will compare the two approaches in 80 adults, measuring the need for extra pain medication during the pro…

This trial tests whether laser acupuncture, a non-invasive therapy using low-intensity light on traditional acupoints, can relieve constipation in people with advanced cancer. Participants are adults with advanced cancer who have constipation despite using laxatives. The study me…

This study tested whether a pharmacist-led program could safely reduce the number of unnecessary medications taken by older adults (65+) with curable cancers starting chemotherapy. 51 patients participated, with oncologists randomly assigned to either a pharmacist review or a sim…

This study tested a new way to help cancer patients quit smoking before their surgery. 282 adults with cancer or suspected cancer who smoked daily took part. Half received standard counseling and nicotine patches, while the other half also got extra rewards for staying smoke-free…

This study tests whether a mobile app can teach family caregivers safe massage techniques to help cancer survivors with long-term nerve pain and numbness caused by chemotherapy. About 300 participants (survivors and their caregivers) will use the app at home. The goal is to reduc…

This study explores whether engaging in positive activities can improve emotional well-being and quality of life for Asian American cancer patients and their caregivers. Participants, who are within a year of a cancer diagnosis and undergoing treatment, along with their caregiver…

This trial tests whether combining pranayama breathing exercises with music listening can help manage fatigue and improve quality of life in cancer patients receiving immunotherapy. Sixty participants are split into two groups: one receives the integrative therapy alongside their…

This trial tests whether a new care approach, called PediQUEST Response, can improve quality of life for children, adolescents, and young adults with advanced cancer. Participants use an app to regularly report symptoms and quality of life, and a palliative care team receives the…

This study tests whether a music-assisted mandala coloring activity can improve psychological well-being and quality of life in adults receiving their first chemotherapy treatment for cancer. Participants will color mandalas weekly for 8 weeks, guided by an instructional video, a…

This study tests whether a short, personalized music listening session with a therapist can lower anxiety, stress, and pain in cancer patients starting radiation therapy. 72 adults will be randomly assigned to receive music therapy during their first radiation session or standard…

This trial tests whether a web-based educational program can help people with advanced cancer reduce their preference for aggressive life-sustaining treatments. Participants are randomly assigned to receive either the web program plus an informational leaflet, or the leaflet alon…

This study compared telemedicine follow-ups to standard in-person clinic visits for cancer patients with chronic pain. Researchers measured how much pain interfered with daily activities using a standard questionnaire. The goal was to see if remote care could be as effective and …

This study tests PAfitME™, a telehealth program that uses personalized motion exergames to help young adult cancer survivors (ages 18–39) improve their physical function. The program is tailored to each person's fitness level, fatigue, and pain. Researchers will see if it is feas…

This study tests whether limiting food intake to a 10-hour window each day for 12 weeks can reduce persistent fatigue in cancer survivors who completed treatment 2 months to 2 years ago. Half the participants follow the eating schedule; the other half receive general healthy life…

This study tests whether graded motor imagery—a brain-based therapy involving left/right judgment, imagined movements, and mirror exercises—can relieve nerve pain and improve leg function in cancer patients with chemotherapy-induced peripheral neuropathy. Half the participants wi…

This study tests whether a serious video game called Strong Together can help women with advanced cancer learn self-advocacy skills. Participants play through scenarios where they make decisions for characters with cancer, learning how to communicate better with doctors and manag…

This study tests whether offering free legal navigation services to cancer patients and their caregivers can reduce financial stress and improve quality of life. About 60 adults who have or care for someone with cancer and face legal barriers to care will receive direct legal hel…

This study tests whether isometric hand exercises or applying dry heat can make veins fuller and easier to see in cancer patients receiving chemotherapy. A total of 180 patients were randomly assigned to one of three groups: isometric exercise, dry heat, or standard care. The goa…

This study tested a 5-week digital program called EMPOWER that teaches emotion regulation skills to adolescent and young adult cancer survivors. 352 participants completed weekly lessons and brief daily exercises. The goal was to see if the program could improve positive feelings…

This study tests whether listening to traditional Chinese guzheng music and smelling lavender essential oil can reduce anxiety in cancer patients undergoing MRI scans. Participants are randomly assigned to receive music, aromatherapy, both, or standard care. The researchers will …

This study tests a smartphone app called STAMP+CBT that combines pain coping skills training with medication support for people with advanced cancer who have chronic pain. The app provides tailored education and real-time feedback to help users manage their pain. Researchers want…

This study is testing whether a mobile app that combines daily symptom reports with Fitbit data can help cancer patients better manage side effects during chemotherapy. Fifty adults with solid tumors will use the app for 90 days, receiving tips for mild symptoms and alerts to con…

This study tested whether Benson relaxation exercises can improve sleep quality in cancer patients. 72 adults with cancer were randomly assigned to do relaxation exercises or receive a sleep hygiene booklet. The goal was to see if this simple, non-drug method could help with slee…

This study tested whether putting special elastic tape on the belly can help relieve severe pain, bloating, and nausea in people with advanced cancer who have bowel blockage and fluid buildup. 38 adults whose symptoms didn't improve after standard treatments were randomly assigne…

This study tested three non-drug methods to reduce pain, fear, and anxiety during subcutaneous injections in 45 children aged 6–12 with cancer. The approaches were Buzzy® (a device that vibrates and cools the skin), a cognitive-behavioral coaching package, and a kaleidoscope for …

This study tested whether a one-week physiotherapy program could improve movement, walking, and daily independence in 32 advanced cancer patients receiving palliative care. The program included exercises, mobility training, and breathing therapy tailored to each patient. Research…

This study tested whether art therapy or mandala coloring can reduce anxiety in people receiving chemotherapy. Sixty adults were randomly assigned to either draw with their eyes closed or color a mandala design during treatment. Researchers measured anxiety levels before and afte…

This study looked at whether teaching cancer patients about their portable chemotherapy pump (elastomeric pump) can make them feel more comfortable and less anxious. 70 adults receiving 5-FU treatment were split into two groups: one got extra education and a booklet, the other go…

This study tested a support program for people caring for a loved one undergoing a stem cell transplant for blood cancer. The program included 8 online sessions over 12 weeks to teach stress management, coping skills, and communication. 17 caregivers took part, and the study chec…

This pilot study tested whether a 12-week exercise program designed for Punjabi-speaking South Asian cancer patients and their support persons is practical and well-liked. Twelve participants did twice-weekly exercise sessions and filled out questionnaires. The goal was to see if…

This phase 3 trial tested whether giving a continuous, slow infusion of ondansetron (a common anti-nausea drug) plus dexamethasone (a steroid) could better control nausea and vomiting in children undergoing chemotherapy. The study enrolled 28 children aged 1 day to 18 years with …

This study tested a one-month program designed to build inner strength in elderly cancer patients who were feeling demoralized. 66 patients took part, with half receiving the program plus standard care and the other half receiving standard care alone. The goal was to see if the p…

This study tested whether using virtual reality goggles during the insertion of a port needle (a common procedure for chemotherapy) can improve comfort and satisfaction in cancer patients. 92 adults with stage I-III cancer were randomly assigned to either standard care or standar…

This study tested a low-dose fentanyl patch in 14 cancer patients in Taiwan to see if it is safe and tolerable for managing pain. The patch delivers pain medicine through the skin over 28 days. The main goal was to see how many patients dropped out due to side effects, with the h…

This study tested whether naldemedine, a drug already used for opioid-induced constipation, can also prevent nausea and vomiting when cancer patients start strong painkillers. 120 adults with cancer who were beginning opioid therapy took either naldemedine or a placebo for up to …

This study tested a Spanish adaptation of Meaning-Centered Psychotherapy for 92 adults who completed cancer treatment. The therapy aims to help patients find meaning in life and reduce anxiety. Participants attended eight group sessions focused on sources of meaning, facing the f…

This study tested a music therapy program called Meraki for cancer patients receiving palliative care. The goal was to see if three music sessions could improve emotional well-being, reduce anxiety and depression, and boost quality of life. Researchers enrolled 80 patients and me…

This study tested a 3-week program that helps cancer patients identify their personal strengths (like hobbies, social support, or personal qualities) and use them to cope better. 32 adults with different cancers took part in card-sorting sessions, phone calls, and home exercises.…

This study tested a 6-session therapy called Acceptance and Commitment Therapy (ACT) for cancer patients at risk of opioid misuse. 40 adults with cancer and a high score on an opioid risk tool participated. The goal was to see if the therapy was feasible and acceptable, not yet t…

This study tested whether coloring mandala patterns can reduce nausea, vomiting, and fatigue, and improve psychological well-being in cancer patients receiving chemotherapy. 85 patients were split into a coloring group and a control group. The coloring session lasted 20-30 minute…

This study tested a 12-week online mind-body program for adults with chronic conditions like heart failure, cancer, and liver disease. The program included mindful movement, meditation, breathwork, and coping skills. Researchers measured changes in anxiety, depression, fatigue, a…

This pilot study tested whether taking a green tea extract (EGCG) plus vitamin C daily for 12 weeks is safe and feasible for older cancer survivors who are frail or pre-frail. The study enrolled 24 people aged 65 and older who had completed cancer treatment. The main goal was to …

This study looked at 158 adults with cancer who had fluid buildup around their lungs, making it hard to breathe. It compared two treatments: a long-term catheter placed under the skin to drain fluid at home, versus keyhole surgery to remove fluid and seal the space. The goal was …

This study looked at whether a structured nutrition education program can improve how much and how well cancer patients eat. 80 adults on active cancer treatment were split into two groups: one received personalized nutrition advice, the other did not. Researchers measured their …

This study tested a mobile app called SyMon-SAYS that lets children with cancer report their symptoms weekly to their doctors. The goal was to see if using the app helps manage symptoms and improve quality of life. 216 children and their parents took part, with some using the app…

This study tested a new type of training called ADIE Therapy for breast cancer survivors who often feel anxious even after treatment ends. The training teaches people to better notice their own heartbeat and other body signals. 21 survivors took part in six sessions to see if the…

This study tested whether a program called PRISM (Promoting Resilience in Stress Management) could help young adults aged 18-39 who have cancer or desmoid tumors manage anxiety and depression. The program teaches skills like stress management, goal setting, and positive thinking.…

This study tested an 8-week supervised program of breathing exercises and light strength training for 30 people with advanced lung cancer (stage IIIB/IV) who were also getting chemotherapy. Those in the rehab group could walk farther, breathe better, and reported less coughing an…

This study tested a system that helps cancer patients manage fatigue. Patients used a phone app to report their tiredness and wore a smartwatch to track activity. Based on their fatigue level, they received personalized exercise advice. The goal was to see if this approach could …

This study tested whether a gentle, light-touch therapy (therapeutic touch) could help advanced cancer patients in palliative care sleep better and feel less tired. Sixty-one patients were randomly assigned to receive either 5 days of 10-15 minute touch sessions or standard care.…

This study tested a 9-session virtual mind-body program (SMART-3RP) to see if it helps caregivers of cancer survivors feel less stressed and more resilient. It compared the program to a standard online support group. The trial enrolled 94 participants and focused on whether the p…

This study tested whether an online exercise and education program could help cancer patients and survivors feel better during the COVID-19 pandemic. Thirty adults with metastatic breast or gynecological cancer, or breast cancer survivors, took part. The program aimed to reduce f…

This study tested whether a talking therapy called dignity therapy can improve feelings of dignity and self-esteem in people with end-stage cancer. 48 patients were randomly assigned to receive either dignity therapy or usual care. The therapy involved five sessions discussing pe…

This study tested a sleep improvement program for people with cancer and their intimate partners who also have sleep problems. The goal was to reduce insomnia and improve sleep quality. Only 2 couples took part, so results are very limited.

This study tested an online program to help cancer patients with insomnia. It included 348 adults with cancer who had trouble sleeping. The program used cognitive-behavioral techniques and aimed to see who might need extra help from a professional.

This study tested whether mild electrical pulses on specific acupoints could reduce nausea and vomiting caused by cisplatin chemotherapy. Thirty-four cancer patients received the stimulation during treatment. The goal was to see if this drug-free approach could ease these common …

This study tested whether an education and support program can help family caregivers of cancer patients feel more confident and less anxious. About 484 caregivers and patients took part. Researchers compared different types of support to see which worked best.

This study tested whether a program that combines behavioral activation (a type of counseling that helps people engage in meaningful activities) with medication optimization (reviewing and adjusting current medications) can reduce anxiety and depression in adults aged 60 and olde…

This study tested a device that delivers pain medicine directly to the spinal cord for cancer patients with severe pain not controlled by oral opioids. Researchers compared the pump to standard medical management in 30 adults. The goal was to see if the pump reduces pain intensit…

This study tested whether using a low-frequency laser on an acupuncture point (P6) can help prevent nausea and vomiting caused by chemotherapy in children aged 2 to 20. The 30 participants received the laser treatment alongside standard anti-nausea drugs. The goal was to see if a…

This pilot study tested whether a 10-minute virtual reality mindfulness program could help cancer patients relax before their radiation simulation. 25 adults scheduled for radiation planning used a VR headset to practice breathing exercises in a calming virtual environment. The m…

This study tested a program called YATAC, designed to help young adults (ages 18-39) recover from cancer and return to everyday life. The program covers goal-setting, managing daily life, staying active, coping with emotions, education, work, finances, relationships, and peer sup…

This study tested a psychological program to help caregivers of stem cell transplant patients cope better. 100 caregivers were split into two groups: one received the coping program, the other standard care. The goal was to see if the program was practical and improved caregivers…

This study tested a 6-month program called CancerPEP that sends daily emails to cancer patients and survivors with tips on exercise, yoga, stress reduction, and healthy eating. The goal was to see if the program is practical and helps improve mental and physical health. 104 adult…

This study tested a telephone-based collaborative care program for 516 people with stage III or IV cancer. The program included regular check-ins, personalized exercise plans, and help managing treatment side effects. The goal was to see if it could improve mobility, reduce pain,…

This study tested whether virtual reality (VR) can reduce pain and distress in children with cancer when they get a needle put into their port-a-cath. 84 children aged 5 to 17 were randomly assigned to use VR, an iPad, or no special distraction during the procedure. Researchers m…

This study tested whether family-focused grief therapy (FFGT) helps families cope when a member has advanced cancer. 700 families were randomly assigned to standard care, 6 therapy sessions, or 10 sessions. The goal was to prevent depression and improve communication during palli…

This study tested an online educational program for cancer patients receiving chemotherapy. The program included video sessions, peer discussions, and digital materials to help with symptom management and emotional coping. Researchers compared 212 patients who used the program to…

This study tested whether mindfulness meditation training could help patients who are undergoing a stem cell transplant and staying in a sterile room. 70 adult patients participated, and the researchers measured their anxiety and sleep quality before and after the meditation prac…

This study looked at whether cancer patients prefer doing yoga online or in a studio during their treatment. 163 people with cancer chose their preferred setting and attended weekly group yoga for 12 weeks. Researchers measured quality of life and interviewed participants about t…

This phase 3 trial tested a drug called APF530, given as a shot, to prevent nausea and vomiting caused by chemotherapy. Over 1,400 cancer patients took part, comparing APF530 with the standard drug Aloxi. The goal was to see if APF530 could keep patients from vomiting or needing …

This phase 3 trial tested whether a new drug called APF530, given as a shot under the skin, works better than the standard drug ondansetron for preventing nausea and vomiting after strong chemotherapy. About 942 cancer patients took part. The study compared both drugs when combin…

This study tested a program that mixes traditional Chinese medicine with standard Western hospital care to help reduce cancer-related fatigue. 86 adults with cancer took part while in the hospital. The main goal was to see if their fatigue levels improved from their worst point t…

This study tested a stepped-care telehealth program for cancer survivors living in rural areas who experience anxiety, depression, or sleep problems. Participants received either low-intensity check-ins or high-intensity phone therapy with a licensed therapist, depending on sympt…

This study tested an online sleep education program for young adult cancer survivors (ages 20-39) who have trouble sleeping. Participants took a single online session, with some also getting extra coaching. The goal was to see if it could reduce insomnia and improve mood. The stu…

This study tested an implantable pump that delivers pain medicine directly into the spinal fluid for people with hard-to-treat cancer pain. Eight patients with advanced cancer and severe pain despite strong opioids took part. The goal was to see if the pump could provide better p…

This study looked at whether cancer patients already taking strong opioids like morphine can stop taking paracetamol without their pain getting worse. 204 adults with metastatic cancer and stable pain on both medications were randomly assigned to continue paracetamol or switch to…

This study tested a smartphone app called Compas-Y, designed to help people with cancer manage emotional distress through self-compassion exercises. 28 adults who had finished cancer treatment and felt low well-being used the app for 6 weeks. Researchers measured changes in self-…

This study tested whether a non-invasive brain stimulation method called iTBS can help cancer survivors who have memory and concentration problems after chemotherapy (often called 'chemo brain'). Fifteen adults who had completed cancer treatment received the stimulation, and rese…

This study tested a smartphone app called POSTHOC that helps cancer survivors manage symptoms and track healthy behaviors after finishing treatment. Fifty-one adults who recently completed cancer therapy used the app or received standard care for 12 weeks. The goal was to see if …

This study tested whether a single online education session can help cancer survivors with insomnia sleep better. 70 survivors took part, learning either behavioral changes to improve sleep or relaxation techniques. The goal was to see if a simple, accessible program could ease i…

This study tested whether asking cancer patients to complete a symptom questionnaire online before their doctor visit could help identify who might benefit from a palliative care referral. Forty adults with advanced cancer participated. The goal was to see if this approach is pra…

This study looked at whether a 12-week adapted physical activity program could help cancer patients feel less tired and improve their quality of life. 37 adults with different cancer types and treatments took part. Researchers measured fatigue, quality of life, and fear of moveme…

This study tested whether wearing virtual reality glasses to visit a museum during chemotherapy could help reduce pain, fatigue, and anxiety. 64 patients were split into two groups: one received routine care, while the other also took a 20-minute virtual museum tour each week for…

This study tested a program that teaches couples communication skills when one partner has advanced cancer. About 440 patients and their partners took part, with half receiving the training and half getting general healthy living information. The goal was to see if the training c…

This study tested a topical cannabidiol (CBD) cream against a placebo cream to see if it could reduce nerve pain, numbness, and tingling in the hands and feet caused by chemotherapy. Forty adults with moderate to severe chemotherapy-induced peripheral neuropathy (CIPN) applied th…

This study tested an 8-week phone- and app-based program designed to increase hope and reduce life disruption in young adults who have finished cancer treatment. 155 survivors participated in a randomized trial comparing the hope program to a control group. The goal was to see if…

This study tested a modified telehealth program called MAAT-YS for young adult survivors of childhood cancer (ages 18-39) who have memory or attention problems from their past treatment. Seven participants completed 8 weekly video sessions and homework to improve their cognitive …

This study looked at whether adding acupuncture to standard recovery care helps colon cancer patients get their digestion back on track faster after surgery. 70 patients were split into two groups: one got standard care, the other got standard care plus acupuncture sessions. Thos…

This study tested a program called CAFÉ, where financial navigators helped cancer patients with money concerns after diagnosis. The goal was to reduce financial hardship and improve quality of life. 371 patients from two Kaiser Permanente regions took part. The program provided p…

This study looked at whether 16 weeks of strength training can reduce long-term side effects in teens aged 10-19 who finished treatment for leukemia or lymphoma. Participants did either strength exercises with weights or circuit training with bodyweight and equipment. The goal wa…

This study tested whether adding manual acupuncture to standard anxiety treatments (medication and talk therapy) helps cancer patients feel less anxious and improves their quality of life. Thirty-eight cancer patients with moderate to severe anxiety received either real acupunctu…

This study tested whether a telemonitoring app called Cureety could reduce the number of phone calls hospital staff receive from cancer patients starting oral or IV treatment. 86 adults with cancer were randomly assigned to standard care or standard care plus the app. The goal wa…

This study tested a monthly online peer support group for young adults (ages 18-39) who had received a stem cell transplant. The group met for one hour over six months, led by a nurse and social worker. The goal was to see if the program was practical and helpful for reducing anx…

This study tested whether a mobile app that lets cancer patients report their symptoms to their doctor can reduce unplanned hospital visits. 166 adults with solid cancers on systemic therapy participated. Half used the app before clinic visits, while the other half had usual care…

This study tested a 4-week online mindful compassion program for women who had finished cancer treatment and were in hospice care at home. The goal was to see if it could improve sexual function, well-being, and quality of life. Twenty-two women took part, and the program include…

This study tested whether inhaling geranium essential oil can reduce nausea and vomiting in cancer patients receiving chemotherapy. 90 participants were randomly assigned to either inhale geranium oil during chemo or receive no aromatherapy. Nausea and vomiting were measured befo…

This study tested whether an 8-week sleep coaching program delivered through a smartphone app is practical and acceptable for cancer survivors and their bedroom partners. Forty participants were enrolled to see if they would stick with the program and find it helpful. The goal wa…

This study tested a short-term talking therapy (psychodynamic psychotherapy) for 24 adults with advanced solid tumors and high psychological distress. The goal was to see if the therapy is safe, acceptable, and feasible, not to cure the cancer. Results will help design larger stu…

This study looked at whether a walking platform with fall protection and support is practical for older cancer patients (over 70) during hospital stays. 45 patients were enrolled to see if they would use it at least twice for 6 minutes or more. The goal was to help them stay acti…

This study tested a mobile app called HopeMove designed to help teenagers with cancer stay physically active and reduce fatigue. Fifteen adolescents aged 13 to 18 who were receiving cancer treatment used the app for four weeks, doing guided exercises at least three times a week. …

This study tested a program called PRISM that teaches stress management, goal-setting, and coping skills to adolescents and young adults (ages 12-24) with advanced cancer. Researchers wanted to see if it could improve quality of life and reduce anxiety and depression. The program…

This study looked at whether listening to relaxing Turkish music for 30 minutes could help cancer patients in palliative care feel less pain and anxiety. 32 patients took part, with half listening to music and the other half resting quietly. The researchers measured pain, anxiety…

This study tested a program to help older cancer patients get stronger before and after surgery. 148 patients aged 70+ (or 60+ with other health issues) took part. The program included exercise, nutrition advice, and education to reduce complications and improve recovery.

This completed trial tested whether virtual clinics offering exercise sessions and psychological support could help cancer patients maintain physical and mental health while following COVID-19 social distancing rules. Over 1,100 adults with suspected or confirmed cancer took part…

This study tested whether a nasal spray made from rose geranium in sesame oil can improve symptoms of nasal vestibulitis—like dryness, discomfort, bleeding, and scabbing—in cancer patients receiving chemotherapy. Over 100 participants were randomly assigned to use either the rose…

This study tested if the drug Akynzeo can prevent nausea and vomiting in cancer patients getting moderate chemotherapy who are at high risk based on a special prediction tool. Over 400 adults took part. The goal was to see if Akynzeo works better than standard care over three rou…

This study tested a nurse-led program to help adults with cancer who are taking part in early-phase clinical trials feel better day-to-day. The program included regular check-ins on symptoms and well-being, plus team meetings to address concerns. Researchers wanted to see if the …

This study tested a financial navigation program for cancer patients in rural and non-rural North Carolina. The program helped patients find financial assistance to reduce the burden of cancer costs. Researchers measured changes in financial toxicity and quality of life in 258 pa…

This study tested a telehealth program called Dyadic Life Review (DLR) for older adults (65+) with advanced cancer and mild cognitive impairment, along with their caregivers. The program involved 8 weekly video sessions where patients and caregivers shared memories from different…

This study tested whether mangafodipir, an MRI contrast agent with antioxidant properties, could reduce nerve damage caused by oxaliplatin chemotherapy. Researchers enrolled 23 cancer patients who already had moderate nerve problems from oxaliplatin but needed to continue treatme…

This study tested a mobile app called STAMP+CBT for advanced cancer patients with chronic pain. The app helps patients track their pain, mood, and opioid use while providing tailored education and cognitive behavioral therapy (CBT) exercises. Fifty-two patients used the app for 4…

This completed pilot study tested a 12-week home-based exercise program for cancer survivors who also have diabetes or hypertension. The program used a wearable device and smartphone app to track activity and provide feedback, with options like walking, yoga, or strength exercise…

This study looked at whether a 12-week home exercise program using mobile technology could reduce fatigue in cancer survivors. 110 adults who had finished cancer treatment or were on immunotherapy took part. Some also tried acupressure or brief mindfulness exercises. The goal was…

This study tested whether using a virtual reality headset during cancer surgery under local anesthesia can reduce pain and anxiety. 42 adults with cancer were randomly assigned to receive either local anesthesia alone or local anesthesia plus VR. The VR used hypnosis and relaxati…

This study tested a patient education program for 167 cancer patients with moderate to severe pain. The program included identifying patient needs, setting goals, and tailored learning activities. Researchers measured whether the program reduced how much pain interfered with dail…

This study looked at whether adding heart rate biofeedback training to regular physical activity can improve quality of life for people who have finished treatment for blood cancers. 80 adults in remission took part. The goal was to see if this combination helps them feel better …

This study tested whether a digital platform called Cureety could reduce the number of phone calls hospital staff need to make to cancer patients before their injectable treatments. 192 adults starting injectable cancer therapy in France were randomly assigned to usual care or us…

This study tested whether using augmented virtual reality (AVR) during chemotherapy can help reduce pain, stress, and anxiety while boosting self-confidence. 150 adult cancer patients in the West Bank were split into two groups: one received standard care, and the other used AVR …

This study tested three types of medicinal cannabis oil (with different levels of THC and CBD) against a placebo in 91 cancer patients. The goal was to see which oil, if any, helps with pain, nausea, anxiety, and sleep problems. Each patient tried multiple oils and a placebo in a…

This completed phase 3 trial tested whether taking psyllium husk fiber capsules during pelvic radiation therapy could reduce gut inflammation and urgency symptoms. 354 adults with pelvic cancers (like rectal, prostate, or gynecological) took either fiber or placebo capsules daily…

This study tested whether a numbing medicine called ropivacaine, given through a chest tube, can reduce severe pain after lung cancer surgery. 90 adults having a thoracotomy (chest opening) for cancer received either ropivacaine or a saltwater placebo every 6 hours for 2 days. Th…

This study looked at whether four well-being treatments — foot reflexology, socio-aesthetics (beauty and skincare), sophrology (a relaxation technique), and singing — can help reduce pain in people with cancer. 180 adult cancer patients took part. The goal was to see if these non…

This study tested two simple changes to hospital wheelchairs: a holder to keep IV poles attached during transport, and a more comfortable seat. Researchers wanted to see if these upgrades could shorten travel time and reduce pain for cancer patients being moved around the hospita…

This early-stage study tests a new formulation of the cancer drug HRS-2189 in 28 healthy adults aged 18-45. The goal is to compare how the body absorbs the new versus the old tablet version and to check for safety. Participants will take a single dose of each formulation in rando…

Researchers are studying whether daily step counts and other smartwatch measurements can predict which cancer patients will be readmitted to the hospital after discharge. Adults who have just left an oncology ward wear a Huawei smartwatch for 30 days to track steps, heart rate, a…

This study looked at the emotional and practical challenges faced by patients with incurable cancer and their caregivers when planning to return home for end-of-life care. Researchers measured how each person perceived the burden, using surveys and statistical analysis to find fa…

This study looked at whether standard radiation treatment for cancer that has spread to the brain causes changes in thinking skills like memory and attention. 35 adults with brain metastases received radiation and took tests and surveys before and after treatment. The goal was to…

Researchers are testing two ways to train VA primary care clinicians to hold goals of care conversations with veterans who have serious illnesses such as cancer, heart failure, or dementia. One approach gives clinicians written materials and online training. The other adds team f…

This study looked at whether offering genetic testing to all young adults with cancer (ages 18-39) is better than only testing those who meet certain guidelines. About 749 participants were randomly assigned to either universal testing with a broad gene panel or standard testing …

Researchers in seven European and Latin American countries ask bereaved relatives to complete the CODE questionnaire about two months after a family member died of cancer in hospital. The survey asks whether patients were treated with dignity and respect and whether relatives fel…

This large observational study looks at whether getting an mRNA COVID-19 vaccine shortly before or after starting immune checkpoint inhibitor therapy is linked to longer survival in adults with cancer. Using data from nearly 100,000 patients in France, researchers are comparing t…

This study tests a digital platform called ConnectedNest that helps cancer patients find and connect with social services like housing assistance, food aid, and financial help. About 400 adults with cancer in Minnesota will use the platform for 90 days. Researchers will measure i…

This study looked at whether teaching mothers about their family health history can help them encourage healthier eating and exercise in their families. About 310 adults with at least one child took part. Researchers gave them a Family Health Package with personalized risk info a…

This study examines whether a routine blood test called Mean Platelet Volume (MPV), taken when a cancer patient is admitted to the intensive care unit (ICU), can help predict their risk of dying. Researchers will review the medical records of 425 adult cancer patients who stayed …

This study tested a document called Voicing My CHOiCES, designed to help young adults (ages 18-39) with serious illnesses like cancer or HIV discuss their care preferences. Participants filled out questionnaires about anxiety, social support, and communication, then reviewed the …

This pilot study tests a program to help young female cancer survivors in rural Imperial County, California, get reproductive health care that matches their personal goals. The program includes a quick needs assessment during oncology visits, followed by a session with a social w…

This study explored how family members share health information about genetic diseases like sickle cell, diabetes, and cancer. Over 1,000 adults completed surveys or interviews about their family health history and support. The goal was to understand social and relational factors…

This trial tests whether adding a structured key information section to patient leaflets helps people form more accurate expectations about a new cancer drug. Researchers will randomly assign about 2,100 UK adults to read one of three versions of a leaflet for tivozanib, a kidney…

This study tested a new cone-beam CT scanner that takes clearer pictures during radiation therapy for lung, liver, and breast cancers. 31 people participated to see if the new scanner reduces image blurring and improves accuracy. The goal is to help doctors target tumors more pre…

This study surveyed over 3,000 US adults to see how explaining different types of uncertainty about a new cancer drug (like whether it works for all races or has unknown side effects) affects people's willingness to take it. Participants read short statements about what is unknow…

This study tests whether a 3.5-minute educational video shown before a doctor's visit helps cancer patients understand radiation therapy better than standard verbal instructions alone. One hundred patients scheduled for radiation will be randomly assigned to receive either the vi…

This study tested a co-designed nutritional training program for 20 oncology nurses in Vietnam. The program included a three-day workshop with theory and hands-on practice, focusing on managing diet-related side effects of cancer treatment like nausea and diarrhea. Researchers me…

This study looked at skin problems caused by targeted cancer therapies. Researchers followed 141 cancer patients starting these treatments, recording any skin reactions through exams and photos. The goal was to better understand why these side effects happen and how to manage the…

This trial asks whether the type of red blood cell transfusion given during cancer surgery affects the body's immune response. It compares standard transfusions with leuko-reduced ones, which have white blood cells removed. The study involves 150 cancer patients undergoing curati…

This study looks at whether a short risk-assessment tool, called the CARG score, can predict severe side effects from chemotherapy in cancer patients aged 70 and older. Participants will answer questions about their health and daily function before starting a new chemotherapy reg…

This study looks at how skin conditions related to cancer or cancer treatments affect the well-being of cancer patients and survivors. About 1,025 participants will fill out questionnaires about their skin condition. The goal is to better understand these effects and improve trea…

This observational study looks at whether muscle loss, measured on routine CT scans, is linked to 28-day survival in adults with cancer who are admitted to the intensive care unit (ICU). Researchers will compare muscle quality and nutritional scores between patients who survive a…

This study looked at whether offering genetic counseling by phone or video could help more childhood cancer survivors get genetic testing. About 391 survivors took part, comparing remote counseling to usual care. The goal was to see if remote services increase testing uptake and …

This pilot trial explores whether using a tumor's molecular profile—its gene expression and DNA sequencing—can help doctors choose a personalized treatment plan for children and young adults with high-grade glioma (a type of brain cancer). Participants receive a recommendation fr…

This study is testing a new smartphone app designed to help cancer patients remember to take their oral anticancer medications and report any side effects. The app also helps patients communicate with their care team and find support for financial or social needs. Researchers wil…

This study uses an online questionnaire to explore how people with past or active cancer in France use self-medication, including non-prescription drugs, herbal remedies, and supplements. It aims to understand what products they take, why, and where they get them. The findings co…

This study looks at whether the virus that causes COVID-19 can be found in the semen of men with cancer who are storing sperm before treatment. Researchers will test both the fluid and the sperm cells for the virus and compare results with nasal swabs and blood tests. The goal is…

This study looks at whether getting a yearly LDL cholesterol test could help cancer survivors avoid serious heart problems like heart attacks and strokes. Researchers will analyze health records from over a million cancer survivors in Korea, comparing those who had the test with …

This study reviews existing medical records to understand how blood clots (VTE) are treated in people with active cancer or a history of cancer. Researchers will look at which blood thinners are used, how often clots come back, and the costs involved. No new treatments are given—…

This study looked at how a specific way of thinking, called high-level construal (focusing on the big picture), affects smoking habits. Researchers studied 300 low-income adults aged 25-55 who wanted to quit but had failed before. They used brain scans and surveys to see if this …

This study examines how children under 18 with cancer or a history of a stem cell transplant do when they need a machine called ECMO to help them breathe. Researchers looked at bleeding, infections, and survival rates in children treated at one hospital, and compared survival wit…

This study tested whether machine learning can detect cancer pain by analyzing facial expressions, voice, and speech. 83 people with cancer recorded videos at clinic visits and at home over 3 months. The goal was to see if this technology could classify pain levels in a diverse g…

This study looks at whether using text messages to screen for depression is practical and well-liked by cancer survivors. About 60 adults with cancer will be asked to respond to a short depression questionnaire via text. The goal is to see if this method works better than the usu…

This observational study follows cancer patients undergoing radiotherapy to understand how psychological distress changes over time and whether it affects clinical outcomes like missed appointments or hospitalizations. Participants complete weekly surveys rating their distress an…

This study collects medical information and biological samples (blood, urine, stool, etc.) from 32 cancer patients starting or restarting immunotherapy. The goal is to build a research database to better understand why some patients develop immune-related side effects and how to …

This study is creating a digital program to help East Asian immigrants with cancer build resilience and start conversations about advance care planning with their families. Researchers will interview religious leaders and test the tool with 84 patients to see if it is easy to use…

This study investigates whether PET-CT scans can accurately measure the radiation dose delivered by radioactive spheres during a liver cancer treatment called radioembolization. Researchers will compare scans taken before and after the procedure in patients with liver tumors. The…

This study looks at whether a 12-week program of cooking demonstrations, recipe cards, and free fruit and vegetable bundles can help cancer survivors eat healthier. Only 11 people are taking part, and the main goal is to see if such a program is practical and keeps people interes…

This completed study looked at 130 hospitalized cancer patients to see if hand grip strength could predict short-term outcomes like death within 30 days, ICU admission, or hospital readmission. Researchers measured grip strength within 24 hours of admission using a simple, non-in…

This study investigates how often cancer patients with COVID-19 develop dangerous blood clots (venous thromboembolism). Researchers will screen participants using ultrasound and blood tests to detect clots, whether or not they cause symptoms. The goal is to understand the true ra…

This study explores whether an online educational video can help people living in rural parts of New Hampshire and Vermont learn about cancer research and clinical trials. Researchers will measure changes in knowledge, attitudes, and actual enrollment in cancer studies over six m…

This study looked at whether having a special consultation with a radiotherapy technician (called a manipulator) helps cancer patients feel more informed about their treatment. Researchers enrolled 308 adults with various cancers who were getting radiation therapy. They compared …

This study collects and analyzes health records from 10,000 cancer patients across multiple sites. Researchers will use this real-world data to better understand patient populations, improve clinical trial design, and support drug development. No new treatments are tested—the goa…

This study tested whether a weekly electronic survey could help identify cancer treatment delays and racial differences. About 100 adults with newly diagnosed breast or colorectal cancer who hadn't started treatment yet filled out a short survey each week for 8 weeks. The goal wa…

This study looked at medical records of 204 Brazilian adults with a specific type of advanced breast cancer (HR+/HER2-). The goal was to see which treatments doctors actually use and how patients fare. No new treatments were tested; instead, researchers collected information to u…

This study tested whether a smartphone app called QuestOnco can reliably track side effects in 134 adult cancer patients receiving active treatment. Patients used the app to report symptoms, and researchers compared those reports to standard paper questionnaires. The goal was to …

This completed study collected tongue images and clinical data from 4,100 people—both cancer patients and healthy individuals—to build a database. Researchers plan to use artificial intelligence to analyze tongue features for early cancer screening and diagnosis. The study did no…

This pilot study tested whether a heart MRI could be done safely and effectively in children with cancer who recently had sepsis. The goal was to see if the MRI could find hidden heart inflammation or weakness that standard tests might miss. Only 7 children took part, and the foc…

This study observed 255 cancer patients receiving immunotherapy to understand why some develop skin side effects. Researchers measured immune markers and lipids in the skin and blood. The goal is to identify patterns that could predict or explain these reactions.

This study tested a nutrition program for cancer survivors who are overweight or have obesity. The program included one-on-one counseling with a dietitian, behavioral skills training, and group support. The goal was to see if the program was easy to run and acceptable to particip…

This study examined 41 patients treated for non-tuberculous mycobacteria (NTM) infections, comparing those with and without cancer. The goal was to count side effects from NTM treatment in each group to understand why cancer patients often stop therapy. Researchers hope this will…

This completed study reviewed medical records of 200 adults with cancer who received the drug nivolumab (Opdivo) either as an intravenous infusion or as a subcutaneous injection (Opdivo Qvantig) in community oncology clinics across the United States. The goal was to describe the …

This study tested a program that lets recently hospitalized cancer patients recover at home with remote monitoring of symptoms, vital signs, and weight. The program includes home visits and close communication with the oncology team. Researchers wanted to see if this approach is …

This study analyzed health records from nearly 75,000 people with type 2 diabetes in Hungary to see if different diabetes medications are linked to cancer risk. Researchers compared various drugs, including metformin, and adjusted for age, gender, and other health factors. The go…

This study tested whether providing grocery delivery (via Instacart) and weekly nutrition coaching calls helps cancer survivors who struggle to afford healthy food. Forty survivors who had finished active cancer treatment took part. The goal was to see if this support was practic…

This study measured how two common blood thinners (rivaroxaban and apixaban) behave in 193 adults with active cancer who also had blood clots or atrial fibrillation. Researchers aimed to understand factors like age, weight, and kidney function that affect drug levels. The goal wa…

This study developed an AI model to predict how well bladder cancer responds to treatment before surgery. Researchers used data from 469 patients, including medical images and genetic information, to train the AI. The goal is to help doctors choose the best treatment plan for eac…

This completed study at Sohag Oncology Center tested whether a quality-of-life survey could help match cancer patients' needs with the right supportive care, like pain management or nutrition counseling. Over 4,400 adult cancer patients completed the EORTC QLQ-C30 questionnaire, …

This study tests whether a simple checklist can help Chinese adults in Chicago get recommended cancer screenings and connect with resources for social needs like housing or food. About 600 participants will use the checklist with a navigator's support. The goal is to see if this …

This study tested a new way for doctors to discuss CPR with older, seriously ill patients and their families. Instead of the usual conversation, doctors followed a step-by-step guide that focused on the patient's values and explained why CPR might not help. The goal was to see if…

Researchers tested a new online tool called PIPO that helps doctors estimate how long a cancer patient might live. This information can guide decisions about which patients to enroll in early-phase clinical trials. The study included 586 people who had already joined phase 1 or p…

This study tested a machine learning model that uses electronic health records to predict which cancer patients receiving infusion therapy are at risk of needing emergency care or hospitalization within 30 days. Researchers analyzed data from over 4,700 patients at UCSF. The goal…

This study looked at whether a virtual reality (VR) education program could help first-time radiation therapy patients understand their treatment better and reduce anxiety and depression. 84 cancer patients were split into two groups: one received VR education, the other standard…

This study tested whether a specialized cancer care center could be set up in a local community clinic in Bangkok, Thailand, instead of a large hospital. Researchers included 358 patients, family members, and healthcare workers to see if the model improved access and satisfaction…

This pilot study tested a program called GUIDE, which uses a trained navigator to help cancer patients overcome social and financial barriers to joining clinical trials. The study included 100 adults with cancer who were eligible for a trial and had at least one health-related so…

This completed study looked at whether adding a warning prompt above cancer misinformation posts on social media encourages people to flag them. Researchers recruited 294 US adults who had either been diagnosed with cancer or cared for someone with cancer. Participants saw fake s…

This study tested whether a special MRI scan (31P-MRS) can detect early signs of damage to heart and muscle cells caused by chemotherapy drugs like doxorubicin. Twelve cancer patients scheduled for chemo underwent three scans over time. The goal was to see if the scan could measu…

This study tested a new on-couch imaging system called HyperSight, which takes 3D X-ray pictures (CBCT) of cancer patients right before their radiation treatment. 46 adults with head/neck, chest, abdomen, or pelvic cancers received both the new HyperSight scan and a standard scan…

This study looked at how the DASH diet changes gut bacteria compared to a standard American diet. Over 100 Black and white adults in Alabama ate either the DASH diet or a typical diet for 28 days. Researchers measured changes in gut microbes, bile acids, and inflammation to see i…

This study looked at whether it's possible to measure muscle mass and physical function in children (ages 8-21) with newly diagnosed solid tumors or lymphoma during cancer treatment. Researchers used simple tests like a 6-minute walk and a special drink to measure muscle, along w…

This study tracked 295 adults who had high-risk surgery for stomach, esophagus, pancreas, or liver cancer. Researchers measured quality of life before surgery and again at 6 and 12 months after. They also asked patients and their family members if they regretted the decision to h…

This study looked at how cancer patients, the general public, and healthcare professionals use and feel about large language models (like ChatGPT) for making cancer treatment decisions. Over 7,000 people from 30 countries completed a survey. The goal was to understand current usa…

This study looked at how trust and communication (called a therapeutic alliance) between Latino/a advanced cancer patients and their oncologists might affect care. Researchers interviewed 4 doctors and held focus groups with 10 patients to understand barriers and what helps build…

This study tested whether a flexible, personalized exercise program is practical for cancer patients receiving chemotherapy. Twenty-one adults with breast, ovarian, or colorectal cancer took part. The main goal was to see if patients would join, attend, and stick with the exercis…

This study looked at 330 older adults (65+) who had cancer surgery to see if low albumin levels before surgery led to more complications. Researchers compared patients with low albumin to those with normal levels, tracking problems like infections, hospital stay length, and ICU n…

This study tested whether a tool called the ARISCAT score can predict lung complications (like pneumonia or collapsed lung) after major abdominal cancer surgery. Researchers followed 410 adults who had surgery under general anesthesia. The goal was to see if the score could help …

This study aimed to improve how we measure quality of life in cancer patients whose disease is progressing. Researchers interviewed 20 patients, their carers, and healthcare professionals to learn their preferences on how often and in what way to collect this information. The goa…

This study looked at how cancer patients feel about returning to work while undergoing treatment. Researchers interviewed 20 patients to understand their needs and how work affects their sense of normalcy. The goal is to help nurses provide better support for work-related challen…

This study looked at 135 people with advanced lung cancer, lymphoma, or other tumors treated with immunotherapy drugs called checkpoint inhibitors. Researchers collected blood and tumor samples over time to measure immune cells and molecules that might predict whether the treatme…

This study looked at the needs and challenges of family caregivers who help older adults (70+) with cancer. Researchers interviewed 78 caregivers to understand their social and personal situations, and tested a personalized support program with phone follow-ups. The goal was to s…

This study looked at how common iron deficiency is in cancer patients starting chemotherapy. Researchers checked iron levels in 480 adults with solid tumors or lymphoma. The goal was to find out how many patients might benefit from iron injections, without using other drugs like …

This completed study followed 360 adults and children with chronic respiratory and other medical conditions to see how their immune systems responded to COVID-19 vaccines over 18 months. Researchers measured antibody, T cell, and B cell levels before vaccination and every 3 month…

This study tested two different PET-CT scanners to see which one is better at finding very small cancer spots (less than 1 cm) in patients. Twenty-four people with cancer each had two scans, one on each machine. The researchers then added virtual lesions to the images to compare …

This study looked at whether children with cancer who watch mukbang (eating shows) have better appetite during hospital treatment. Researchers tracked 179 children's eating habits and video watching over several days. The goal was to see if there's a link that could help improve …

This study looks at whether certain combinations of genetic variations, rather than a single gene, can increase the risk of colorectal cancer. Researchers will compare the DNA of 700 patients with strong family histories of the disease against 350 healthy controls. The goal is to…

This completed study looked at how well COVID-19 vaccines trigger an immune response in children and young adults (under 24) with cancer or who had a transplant or cellular therapy. Researchers measured antibody and T-cell levels after vaccination. The goal was to learn more abou…

This completed study looked at 300 cancer patients treated with immune checkpoint inhibitors to see if measuring troponin levels could help detect serious heart problems early. The goal was to prevent major cardiovascular events like heart attack or stroke without unnecessarily s…

This study looked at how immune checkpoint inhibitors, a type of cancer drug, might affect blood vessels and increase heart risks. Researchers measured blood vessel function and checked for related markers in 39 cancer patients before and after starting treatment. The goal was to…

This study tested new ways to make genetic counseling more helpful for people from all backgrounds. Over 1,000 adults completed surveys and allowed their counseling sessions to be recorded. The goal was to see if different counseling methods lead to better experiences, especially…

This study tested a program called GRACE that helps primary care patients assess their risk for diseases like heart disease, cancer, and liver disease using family health history. Researchers enrolled 245 patients from five clinics, including low-resource settings, to see how man…

This completed study tested a new tool called Life S-Can that quickly checks diet, exercise, sleep, and mental health in cancer survivors. 105 survivors used the tool and some received extra coaching from health experts. The goal was to see if the tool helps doctors give better s…

This study tested whether community health navigators who use American Sign Language (ASL) via videoconferencing could help deaf, deafblind, and hard-of-hearing adults complete recommended cancer screenings. The 184 participants were aged 45-80 and had early hearing loss. The nav…

This study looked at nearly 1,000 cancer survivors to find out which follow-up care model works best for their quality of life and satisfaction. Participants were breast, prostate, or colorectal cancer survivors who had finished active treatment. Researchers compared different ca…

This study looked at whether people with advanced cancers (melanoma, kidney, or lung cancer) receiving their first immunotherapy treatment could successfully collect small blood samples at home using a finger-prick method. The goal was to see if this approach is practical and rel…

This study gathered information from nearly 3,000 cancer patients aged 65 and older to learn more about their health, living situations, and the care they receive. No new treatments were tested. The goal was to create a database that helps doctors and researchers better understan…

This completed study involved 633 participants and aimed to develop two clinical tools to identify and measure stigma experienced by children with cancer and their caregivers. Researchers worked in the United States, Guatemala, and Jordan to ensure the tools are culturally releva…

This study looked at how often a muscle enzyme called CPK increases in people with solid tumors who are taking a type of targeted therapy called tyrosine kinase inhibitors (TKIs). Researchers measured CPK levels in routine blood tests from 154 patients and checked if high levels …

This study aimed to understand and address financial stress in teens and young adults (ages 15-39) recently treated for cancer. Researchers tested a financial education and navigation program to see if it was helpful and practical. The study involved 26 participants and focused o…

This study looked at how patients with advanced cancer respond to being offered a conversation about their future care preferences. Researchers invited 71 patients to discuss their wishes and tracked who took part. The goal was to learn more about what helps patients feel ready t…

This study looked at 42 adults with advanced solid tumors who were already on or about to start checkpoint inhibitor immunotherapy and also needed palliative radiotherapy for symptom relief. Researchers wanted to see if the combination was safe (less than 30% severe side effects)…

This study looked at whether measuring specific immune responses (anti-telomerase T cells) in the blood can help predict how well cancer patients will respond to immunotherapy drugs like anti-PD1/PDL1. Researchers enrolled 295 adults with advanced or metastatic cancer who were ab…

This study tested a program called FinFit to help adolescent and young adult cancer survivors deal with money problems caused by their illness. Researchers interviewed 16 people from community cancer clinics to design and improve the program. The goal was to figure out the best w…

This study tested whether an artificial intelligence (AI) tool could help primary care doctors more accurately diagnose skin conditions and decide which patients need to see a skin specialist. 131 adults with various skin issues, including possible skin cancer, took part. Doctors…

This study looked at 232 adult cancer patients with sepsis and low blood pressure to see if adding a type of antibiotic called aminoglycosides helps them recover faster. The main goal was to see how quickly their blood pressure returned to normal without needing strong blood pres…

This study looked at how financial problems affect the well-being of hospitalized cancer patients and their caregivers in Turkey. Over 750 patients filled out surveys about their finances, mood, and quality of life. The goal was to understand the link between money stress and car…

This study looked at 3820 adults with cancer who also had COVID-19. Researchers collected routine medical data to describe symptoms and identify factors affecting survival. The goal was to learn more about how COVID-19 affects cancer patients, not to test a new treatment.

This study looked at 30 cancer patients with COVID-19 pneumonia to see if lung ultrasound could work as well as CT scans for diagnosis. Researchers compared the imaging results and checked if they matched the patients' symptoms and lab tests. The goal was to find a cheaper, easie…

This study looked at whether using a Spiritual Needs Questionnaire helps identify and address the spiritual needs of patients in palliative care. About 100 patients with cancer, heart failure, COPD, or ALS took part. The goal was to see if this approach is practical and beneficia…

This study looked at over 1,100 critically ill cancer patients in the ICU to see if iron levels in the blood could help predict who would survive for 30 days. Researchers used artificial intelligence to combine iron markers with other routine lab results. The goal was to create a…

This study tested whether showing cancer survivors real-time glucose data from a wearable sensor can encourage them to be more physically active. 60 cancer survivors at high risk for type 2 diabetes wore a Fitbit and some also wore a continuous glucose monitor for 4 weeks, receiv…

This study looked at whether health questionnaires filled out by childhood cancer survivors and their parents match what doctors find during check-ups. About 300 survivors aged 8 to 18 took part, completing surveys over three years. The goal is to make these questionnaires more a…

This study tested an educational program to help people in rural areas learn more about colorectal cancer screening. 205 adults aged 45-74 from specific counties in New Hampshire and Vermont took part. Researchers measured changes in knowledge and intentions to get screened befor…

This study looked at 103 diabetic adults starting chemotherapy for cancer. Researchers used a continuous glucose monitor (Freestyle Libre) to track blood sugar changes. The goal was to see how often blood sugar went too low or too high during treatment, since chemotherapy and rel…

This study looked at 32 childhood cancer survivors who had pelvic radiation at least one year earlier. Researchers measured bladder function and bone density to understand long-term side effects. The goal was to gather knowledge, not to test a new treatment.

This study tested a website designed to help people with advanced cancer and their family caregivers talk about advance care planning. Researchers worked with 36 patient-caregiver pairs to see if the website was easy to use and helpful. The main goal was to gather feedback to imp…

This study looked at 33 adults who had both immune thrombocytopenia (ITP) — a condition where the immune system destroys platelets — and cancer. Researchers wanted to see if treating the cancer could also improve ITP. They also investigated whether cancer cells might mimic platel…

This study tested a web-based program called GIFT that helps cancer patients share information about inherited cancer risks with their relatives. Over 3,000 patients and their family members took part. The goal was to see if the tool encourages more relatives to get genetic testi…

This completed study tested a prototype online platform called HModEx that would let researchers share and find health economic models for cancer. Nine expert advisors evaluated how easy it was to search, upload, and review these models. The goal was to see if such a platform cou…

This study looked at whether measuring elastin fragments in blood or urine can help assess frailty in people aged 65 and older with cancer. Frailty is hard to measure with current methods, which can be slow and subjective. The researchers hope that a biological marker could provi…

This study looked at two ways to help people with advanced cancer plan their future medical care: one-on-one talks with a trained nurse or social worker (in person or by phone), or using a website on their own. Over 600 patients took part to see which method helped them think abo…

This study looked at how to gather information about complementary therapies (like massage, yoga, or acupuncture) for children with cancer. Researchers worked with 100 kids to see if it's possible to measure things like pain, nausea, and quality of life during these treatments. T…

This French study asked 49 cancer patients how they felt about switching from hospital to home-based immunotherapy. The goal was to see if home treatment improved their satisfaction with care. It was an observational study, meaning no new treatments were tested—just patient exper…

This study tested whether a machine learning model could predict kidney injury caused by platinum chemotherapy more accurately than doctors. Researchers followed 77 cancer patients receiving cisplatin or carboplatin, tracking their kidney function over time. The goal was to see i…

This study looked at whether sending reminders to cancer patients and alerts to their nurses helps them complete regular symptom questionnaires. Over 476 patients starting a new cancer therapy were split into three groups: usual care, reminders plus nurse alerts during clinic vis…

This pilot study tested whether a mobile program could help young adult cancer survivors (ages 18-39) increase physical activity and improve their diet. The program included behavioral lessons, an activity tracker, and simplified diet monitoring using a traffic-light approach. Th…

This study looked at how well the Pfizer COVID-19 vaccine triggers an immune response in 196 adults with weakened immune systems (due to conditions like kidney transplant, cancer, or HIV) compared to healthy adults. Researchers measured antibody levels and their ability to neutra…

This study tracked 300 cancer patients receiving their first round of chemotherapy to see how often nausea and vomiting still happen, even with standard anti-nausea medicines. Participants filled out questionnaires about their symptoms in the first 24 hours and up to 4 days after…

This study asked 167 people with cancer (and their caregivers) what they value most during pharmacy consultations for oral cancer drugs. Using a survey method, researchers identified key preferences to help hospitals design better support services. The goal was to improve patient…

This study tested a training program for community healthcare providers to improve their knowledge and skills in caring for cancer survivors. Twenty-eight providers from five Ohio hospitals participated in virtual sessions covering topics like long-term side effects, health promo…

This completed study enrolled 200 cancer patients aged 40-85 who were about to start chemotherapy. Researchers tracked symptoms like numbness, daily activity, and falls using surveys, activity monitors, and even smart socks. The goal was to find simple ways for doctors to predict…

This study tested whether using at-home monitoring devices (like a wristband pedometer, scale, and blood pressure cuff) can help improve care for cancer patients after they leave the hospital following surgery. 22 patients with various cancers participated. The goal was to see if…

This completed study observed 178 patients with advanced cancer, chronic kidney failure, or chronic lung diseases to assess their palliative care needs and survival factors. Researchers used two scoring tools to evaluate when and how to best introduce palliative care alongside re…

This study followed over 1,500 women who had pregnancy losses and were tested for antiphospholipid syndrome (APS) and other clotting disorders. Researchers compared cancer rates among women with APS, those with other clotting gene changes, and those with no clotting issues. The g…

This study looked at health-risk behaviors like smoking, alcohol use, diet, and exercise among 46 cancer survivors in France. The goal was to see how common these behaviors are so doctors can better help survivors avoid future health problems. The study found that many survivors …

This study tested whether showing patients videos about advance care planning and training doctors in communication skills helps cancer patients document their care wishes. Over 13,000 patients from multiple clinics took part, with most only having their medical records reviewed.…

This study looks back at 204 patients with untreated, inoperable malignant pleural mesothelioma who received a combination of two immunotherapy drugs, nivolumab and ipilimumab, through an early access program in France. Researchers will collect data from medical records to see ho…

This study tested a questionnaire called PO-BADO that helps doctors and nurses talk with cancer patients and their caregivers. Researchers checked if the questionnaire gives consistent and reliable results. 252 adults with cancer who have a caregiver support time took part. The g…

This study brought together experts to decide what health outcomes matter most when testing cancer treatments in older adults. Instead of focusing only on tumor shrinkage, they identified key areas like independence, memory, mood, and nutrition. The goal is to help future clinica…

This study followed 76 cancer patients over age 70 to see how geriatric tests and social factors affect their quality of life. Researchers wanted to learn how to better tailor chemotherapy and care for older adults. The goal was to improve both well-being and cost-effectiveness o…

This study looked at 700 cancer patients to understand how often dangerous blood clots occur and how blood-thinning medications affect them. Researchers tracked patients over two years, analyzing blood samples and clotting events. The goal is to improve prevention and treatment o…

This study looked at whether having cancer patients report their own symptoms during radiation treatment helps doctors notice and manage side effects better. About 104 adults with lung, esophageal, or other gastrointestinal cancers took part. Doctors reviewed patient-reported sym…

This study looked at over 3,000 people at risk for certain cancers to see if a patient-directed online genetic counseling approach works as well as standard care. Participants were randomly assigned to either use an automated genetics education assistant or receive enhanced stand…

This completed study looked at 12,500 cancer patients who had a type of heart attack called NSTEMI. Researchers compared those who got invasive procedures like angiography versus those treated only with medications. The goal was to see which approach led to fewer deaths in the ho…

This completed study looked at 261 French cancer patients to understand why many do not exercise, despite evidence that physical activity improves survival and well-being. Researchers surveyed patients about their personality, motivation, anxiety, and social background. The goal …

This completed study reviewed medical records of 1,250 advanced cancer patients who visited the emergency department. Researchers looked at factors like age, tumor type, and blood test results to see which patients were at higher risk of dying within 90 days. The goal is to help …

This study followed 153 people with cancer who had or were suspected of having COVID-19. Researchers collected throat swabs and saliva samples over several weeks to see how well antibody and antigen tests work in this group. The goal was to learn more about the course of COVID-19…