Gene combo clues could transform colon cancer risk checks

NCT ID NCT01057953

Completed Knowledge-focused Sponsor: University Hospital, Rouen Source: ClinicalTrials.gov ↗

First seen Apr 20, 2026 · Last updated May 23, 2026 · Updated 4 times

Summary

This study looked at whether certain combinations of gene changes can raise the risk of colorectal cancer (CRC) in people who don't have a known inherited form. Researchers compared 700 patients with strong family history or early-onset CRC to 350 healthy controls. The goal is to better identify high-risk families and guide colonoscopy decisions.

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Contacts and locations

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Locations

CH de Niort

Niort, France
CHRU de Lille

Lille, France
CHU de Dijon

Dijon, France
CHU de Grenoble

Grenoble, France
CHU de Montpellier

Montpellier, France
CHU de Rennes

Rennes, France
CHU de Saint-Etienne

Saint-Etienne, France
CHU de Toulouse

Toulouse, France
CLCC Val d'Aurelle

Montpellier, France
Centre Eugène Marquis

Rennes, 35000, France
Centre François Baclesse

Caen, 14000, France
Hôpital Européen Georges Pompidou

Paris, France
Institut Claudius Regaud

Toulouse, France
Institut Curie

Paris, 75005, France
Institut Gustave Roussy

Villejuif, 94800, France
UHRouen

Rouen, 76031, France

Conditions

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CANCER