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New therapy aims to curb opioid misuse in cancer patients

NCT ID NCT05643027

First seen Jan 05, 2026 · Last updated Jun 23, 2026 · Updated 26 times

Summary

This study tested a 6-session therapy called Acceptance and Commitment Therapy (ACT) for cancer patients at risk of opioid misuse. 40 adults with cancer and a high score on an opioid risk tool participated. The goal was to see if the therapy was feasible and acceptable, not yet to prove it works.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Acceptance and Commitment Therapy (ACT)

What this could lead to

If successful, this therapy could help cancer patients manage psychological symptoms and reduce the risk of opioid misuse.

What could go wrong

This is a small, early-stage pilot study with only 40 participants. It focused on feasibility, not effectiveness, so results may not apply broadly.

Conditions

The condition(s) this trial relates to.

mental disorder neoplasm substance-related disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.