Can talking and tweaking meds calm older cancer surgery patients?
NCT ID NCT05685511
First seen Apr 04, 2026 · Last updated Jun 23, 2026 · Updated 18 times
Summary
This study tested whether a program that combines behavioral activation (a type of counseling that helps people engage in meaningful activities) with medication optimization (reviewing and adjusting current medications) can reduce anxiety and depression in adults aged 60 and older who are about to have surgery for cancer. The 105 participants were randomly assigned to receive the program or usual care. The main goal was to see if their mood scores improved three months after surgery.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Washington University School of Medicine
St Louis, Missouri, 63110, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Behavioral activation (counseling to engage in meaningful activities) and medication optimization (review and adjustment of current medications)
What this could lead to
If it works, this could provide a simple, non-drug way to improve mental health in older adults undergoing cancer surgery.
What could go wrong
This is a small, completed trial (105 participants) without a later phase, so results may not apply broadly. The intervention combines two approaches, making it hard to know which part helped.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.