Can a targeted nerve block replace opioids for chemoport surgery?
NCT ID NCT07771712
First seen Aug 18, 2026 · Last updated Aug 21, 2026 · Updated 3 times
Summary
This trial tests whether a combined nerve block can provide better pain relief than standard local anesthesia for cancer patients undergoing chemoport implantation. The study will compare the two approaches in 80 adults, measuring the need for extra pain medication during the procedure, as well as post-surgery pain and satisfaction. If successful, this technique could reduce opioid use and improve recovery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Combined pectoserratus plane and superficial cervical plexus block using bupivacaine
- What this could lead to
- If effective, this nerve block technique could offer cancer patients a more comfortable chemoport implantation with less pain and fewer opioids.
- What could go wrong
- This is a small, early-stage trial, and the block may not consistently outperform standard care. There are also risks like local anesthetic toxicity or nerve injury.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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80 people
The number who actually took part.
- Started
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Dec 2025
- Finished
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Jun 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Aged 18-65 years. * Diagnosed with cancer requiring elective chemoport implantation for long-term intravenous therapy. * Classified as American Society of Anesthesiologists (ASA) Physical Status II or III. * Scheduled to undergo chemoport implantation under intravenous sedation. * Able to understand the study procedures and provide written informed consent. Exclusion Criteria: * Refusal to participate in the study. * History of burns or infection at the chest wall in the planned injection area. * Presence of a tumor involving the chest wall at the planned injection site. * Known allergy or hypersensitivity to local anesthetic agents. * Obesity, defined as a body mass index (BMI) \>30 kg/m². * Severe coagulation disorders, defined as a platelet count \<50,000/µL or prolonged prothrombin time (PT) and/or activated partial thromboplastin time (aPTT) greater than twice the upper limit of normal.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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MRCCC Siloam Hospitals Semanggi
Jakarta, DKI Jakarta, 12930, Indonesia
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