Firefighters' diet study shows promise for lowering cancer markers
NCT ID NCT06567561
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether eating a whole-food, plant-based diet for 8 weeks could lower markers of cancer and inflammation in firefighters. 121 active firefighters participated. Researchers measured changes in blood markers like IL-6 and C-reactive protein to see if the diet made a difference compared to their usual eating habits.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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121 people
The number who actually took part.
- Started
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Jan 2025
- Finished
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Mar 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 18+ * Active SF firefighter * Willing to consume a plant-based diet (vegetables, fruit, whole grains, legumes, etc.) * Willing to complete 4 clinic visits Exclusion Criteria: * Weight \< 110 lb * BMI \>= 40 * Self-reported uncontrolled hypercholesterolemia, hypertension or diabetes * Pregnant, lactating, or planning to become pregnant during the course of the study. * Use of any of the following drugs/supplements within the last 2 months: * systemic antibiotics, antifungals, antivirals, or antiparasitics (intravenous, intramuscular, or oral); * corticosteroids (intravenous, intramuscular, oral, nasal or inhaled); * cytokines; * methotrexate or immunosuppressive cytotoxic agents. * Chronic, clinically significant, or unstable (unresolved, requiring ongoing changes to medical management or medication) pulmonary, cardiovascular, gastrointestinal, hepatic or renal functional abnormality, as determined by medical history, Type 1 diabetes, dialysis * History of active cancer in the past 3 years except for squamous or basal cell carcinomas of the skin that have been medically managed by local excision * Unstable dietary history as defined by major changes in diet during the previous month, where the subject has eliminated or significantly increased a major food group in the diet. * Recent history of chronic excessive alcohol consumption defined as more than five 1.5-ounce servings of 80 proof distilled spirits, five 12-ounce servings of beer or five 5-ounce servings of wine per day; or \> 14 drinks/week. * Any confirmed or suspected condition/state of immunosuppression or immunodeficiency (primary or acquired) including HIV infection, multiple sclerosis, and Graves' disease. * Surgery of the GI tract, with the exception of cholecystectomy and appendectomy, in the past five years. Any major bowel resection at any time. * Regular/frequent use of smoking or chewing tobacco, e-cigarettes, cigars or other nicotine-containing products * Regular use of prescription opiate pain medication
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Stanford University
Palo Alto, California, 94305, United States
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