MICROBIOME

This study is looking for 400 adults in Portugal, aged 40 to 74, who have recently been diagnosed with colorectal cancer but haven't started treatment yet. Researchers want to see if analyzing the bacteria in a person's stool can help detect cancer earlier and predict outcomes. T…

This study tests whether an online program teaching a high-fiber, gut-healthy diet is feasible for women with triple-negative breast cancer who are receiving immunotherapy and chemotherapy. The goal is to see if the diet can improve treatment effectiveness and reduce side effects…

This study tests whether a probiotic supplement can improve gut health and reduce symptoms in 50 adults with acid reflux (GERD) who are already on standard medication. Participants take either the probiotic or a placebo for 6 weeks. Researchers will check changes in gut and mouth…

This study tests if gently swabbing the noses of C-section babies with their mother's vaginal fluids is safe and can change the germs in their upper airways. About 20 healthy babies will be randomly assigned to get either the real swab or a plain sterile one. The goal is to see i…

This study looks at how different drinks—plain water, water with stevia (a no-calorie sweetener), and water with sugar—change the acidity in the mouth and the bacteria in dental plaque. About 52 Mexican teenagers who regularly drink soda will take part. Researchers want to see wh…

This study follows 600 burn patients and 60 healthy volunteers to see how burns change the bacteria on the skin and in the gut. Researchers will collect samples and measure skin health at several points over two years. The goal is to better understand these changes and find ways …

This study looks at whether giving parents personalized advice based on their baby's gut bacteria can improve gut health and lower the risk of conditions like eczema in infants born by C-section. Researchers will follow 250 babies from birth to age 2, comparing a group that gets …

This study looks at how two cannabis compounds, CBD and THC, affect inflammation and brain health in people with HIV. About 90 participants will take both compounds in a random order over 6 weeks. Researchers will measure blood markers and brain changes to better understand how c…

This study looks at how severe injuries change the brain, bone marrow, and gut, and how these changes lead to long-term anemia and recovery problems. Researchers will study 275 adults with serious blunt trauma to understand these connections. The goal is to gather knowledge that …

This study collects samples (mouth swabs, stool, and small pancreas tissue samples) from 300 adults who may have pancreatic cancer. Researchers want to see if certain bacteria or fungi are linked to the disease, its severity, and patient outcomes. The goal is to find new ways to …

This study looks at how taking a special oil every day for a month changes the bacteria in the gut. Researchers will collect samples from 25 healthy adults to see if the oil boosts certain good bacteria. It is not a treatment for any disease, just a way to learn more about how di…

This study uses advanced genetic sequencing to monitor antibiotic resistance in 800 pneumonia patients. Researchers will compare the types of bacteria and resistance genes found in severe versus mild cases. The goal is to better understand how resistance spreads and to improve tr…

This study looks at why some breast cancer patients get diarrhea from the drug Abemaciclib while others don't. Researchers will compare the gut bacteria of 60 women who have diarrhea with those who don't, using stool samples. The goal is to find if certain bacteria protect agains…

This study looks at bacteria in stool samples from 30,000 people aged 40-74 in Portugal to find new markers for early colorectal cancer detection. Researchers will compare gut microbiome patterns with standard screening tests and colonoscopy results. The goal is to develop a more…

This study looks at how different oral hygiene routines (including mouthwash) affect the bacteria in your mouth, gum inflammation, and overall gum health in people with gingivitis. Over 6 weeks, 250 adults will use assigned products twice daily, with a follow-up 2 weeks after sto…

This study looks at how the bacteria and natural chemicals in couples' bodies might influence the success of IVF treatment. Researchers will collect samples from 1000 couples to see if these factors are linked to pregnancy, miscarriage, or live birth. The goal is to better unders…