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Can family therapy ease grief after cancer? new study tests it

NCT ID NCT00580515

Symptom relief Sponsor: Memorial Sloan Kettering Cancer Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether family-focused grief therapy (FFGT) helps families cope when a member has advanced cancer. 700 families were randomly assigned to standard care, 6 therapy sessions, or 10 sessions. The goal was to prevent depression and improve communication during palliative care and after the patient's death. The therapy involves structured sessions over several months.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Family Focused Group Therapy (FFGT)
What this could lead to
If it works, this could provide a simple, non-drug way to help families cope with grief and reduce depression after losing a loved one to cancer.
What could go wrong
This is a completed trial, but results may not apply to all families. The therapy requires time and commitment, and not everyone may benefit equally.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 700 people

The number the study aims to enrol. It can still change while the study runs.

Started

Nov 2005

Finished

Mar 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

12 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Subject/Patient Inclusion Criteria * Individuals with advanced disease/Stage 4-IV cancer who may be involved in palliative care treatment program. * Individuals with a poor prognosis Patient and Family Member Inclusion Criteria. * Per investigator's judgment participants must have satisfactory cognitive functioning to provide valid informed consent and participate in family therapy. * In the event that the index family member is declining or too frail to take part in family meetings, the family is able to participate without the index patient being involved in the study. * For every enrolled family there must be at least 2 family members willing/able to take part at the time of recruitment. * The presence of FRI screening scores of ≤ 9 or cohesiveness subscale score \< 4 based on the perception of any single family member, including the patient. Exclusion Criteria: * Inability through language to complete the study questionnaires - inability to speak English with an English-speaking therapist. * Age less than 12 years old for a child. * Patient and family member determined geographical inaccessibility to attend family sessions. * Significant psychiatric disturbance sufficient, in the investigator's judgment, to preclude participation in a psychotherapeutic intervention.

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Conditions

The condition(s) this trial relates to.

cancer neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cancer

Contacts and locations

Locations

  • Beth Israel Hospice Program

    New York, New York, 10003, United States

  • Calvary Hospital

    The Bronx, New York, 10461, United States

  • Memorial Sloan-Kettering Cancer Center

    New York, New York, 10065, United States

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