Cancer Patients' blood thinner mystery solved?
NCT ID NCT05819736
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study measured how two common blood thinners (rivaroxaban and apixaban) behave in 193 adults with active cancer who also had blood clots or atrial fibrillation. Researchers aimed to understand factors like age, weight, and kidney function that affect drug levels. The goal was to gather real-world data to guide safer use of these medications in cancer patients.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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193 people
The number who actually took part.
- Started
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Dec 2022
- Finished
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May 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Cancer patients with atrial fibrillation or venous thromboembolism receiving rivaroxaban or apixaban in a real-life clinical setting
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Male or female subjects with age ≥ 18 years * Cancer (other than basal-cell or squamous-cell carcinoma of the skin), either active or diagnosed within 6 months prior to inclusion * Confirmed symptomatic or venous thromboembolism or confirmed atrial fibrillation * Patients affiliated with a health insurance system * Able to provide written informed consent. Exclusion Criteria: * Age \<18 years * Pregnancy or breastfeeding * Patients not affiliated with a health insurance system * Patient subject to a measure of protection * Legally protected adults * Life expectancy \< 3 months
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Centre d'Investigation Clinique Hôpital Pitié-Salpêtrière
Paris, 75013, France
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