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Your voice matters: study tests if patient symptom reports help doctors catch side effects earlier

NCT ID NCT04589247

Knowledge-focused Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether having cancer patients report their own symptoms during radiation treatment helps doctors notice and manage side effects better. About 104 adults with lung, esophageal, or other gastrointestinal cancers took part. Doctors reviewed patient-reported symptom forms before making treatment decisions, and researchers measured how often this changed the doctor's view of the patient's side effect burden.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

104 people

The number who actually took part.

Started

Nov 2020

Finished

Jun 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Our study population will be treating radiation oncologists and their primary cancer patients requiring definitive treatment with radiation with or without concurrent chemotherapy as per the inclusion criteria below. Cancer patients receiving stereotactic body radiation therapy or hypo-fractionated definitive radiation will not be recruited as these patients represent a different treatment population with a much lower overall treatment toxicity burden.

Ages

18 to 100 years

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Men and women over 18 years of age * Able to read and write in English or able to understand/answer questions with the aid of an interpreter * Histologically confirmed loco-regional to advanced primary cancer, including but not limited to lung cancer, esophageal, or gastro-intestinal cancers at risk of developing radiotherapy-related toxicity. * Receiving definitive conventionally-fractionated radiation treatment with or without chemotherapy Exclusion Criteria: * Patients receiving radiation for palliative intent * Patients who do not provide informed consent * Patients who chose to withdraw from the study Radiation Oncologists Inclusion criteria: • Must be the physician overseeing the care of the patient who answers the PROMS Exclusion criteria: • Have not provided informed consent

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Conditions

The condition(s) this trial relates to.

cancer digestive system cancer digestive system neoplasm esophageal cancer lung cancer lung neoplasm neoplasm neoplasm of thorax Thoracic Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cancer Gastrointestinal cancer Lung cancer Thoracic neoplasms

Contacts and locations

Locations

  • Bayview Medical Center

    Baltimore, Maryland, 21227, United States

  • Johns Hopkins Sidney Kimmel Comprehensive Cancer Center

    Baltimore, Maryland, 21231, United States

  • Khinh Voong

    Baltimore, Maryland, 21230, United States

  • Suburban Hospital

    Bethesda, Maryland, 20814, United States

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