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New study tracks COVID vaccine durability in chronic illness patients

NCT ID NCT05313087

First seen Apr 23, 2026 · Last updated Jun 23, 2026 · Updated 11 times

Summary

This completed study followed 360 adults and children with chronic respiratory and other medical conditions to see how their immune systems responded to COVID-19 vaccines over 18 months. Researchers measured antibody, T cell, and B cell levels before vaccination and every 3 months after. The goal was to understand how long vaccine protection lasts in people with ongoing health issues.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • National Jewish Health

    Denver, Colorado, 80206, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

COVID-19 vaccine

What this could lead to

If successful, this study could help doctors understand how long vaccine protection lasts in people with chronic health conditions, guiding booster shot timing.

What could go wrong

This is an observational study, not a treatment trial. It measures immune responses but does not test a new vaccine or therapy. Results may not apply to all patients.

Conditions

The condition(s) this trial relates to.

severe acute respiratory syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.