New study tracks COVID vaccine durability in chronic illness patients

NCT ID NCT05313087

Completed Knowledge-focused Sponsor: National Jewish Health Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study followed 360 adults and children with chronic respiratory and other medical conditions to see how their immune systems responded to COVID-19 vaccines over 18 months. Researchers measured antibody, T cell, and B cell levels before vaccination and every 3 months after. The goal was to understand how long vaccine protection lasts in people with ongoing health issues.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: COVID-19 vaccine
What this could lead to: If successful, this study could help doctors understand how long vaccine protection lasts in people with chronic health conditions, guiding booster shot timing.
What could go wrong: This is an observational study, not a treatment trial. It measures immune responses but does not test a new vaccine or therapy. Results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ASTHMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

asthma bronchiectasis cancer chronic obstructive pulmonary disease cystic fibrosis interstitial lung disease rheumatoid arthritis severe acute respiratory syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SARS-COV INFECTION

Contacts and locations

Locations

National Jewish Health

Denver, Colorado, 80206, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.