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New program aims to help cancer survivors kick the habit and ease pain

NCT ID NCT06029907

Symptom relief Sponsor: Duke University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Aug 26, 2026 · Updated 4 times

Summary

This study tested a program to help cancer survivors quit smoking and manage pain. Nineteen survivors received counseling and the medication varenicline (Chantix). The goal was to see if the program was practical and helpful, not yet to prove it works.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
varenicline (Chantix)
What this could lead to
If successful, this program could offer a practical way to help cancer survivors quit smoking and manage pain at the same time.
What could go wrong
This is a very small pilot study with only 19 participants, so results may not apply to all survivors. The program's effectiveness is still uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

21 people

The number who actually took part.

Started

Jul 2024

Finished

Aug 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients with cancer at our targeted recruitment sites * Have a diagnosis of cancer within the past 5 years (can be currently undergoing treatment) * Have a life expectancy of at least 1 year * Report pain within the last 3 weeks of 3 or higher on a 10 point scale * Have smoked at least 100 cigarettes in their lifetime * Smoke 5 or more cigarettes per day in the prior 7 days * Be willing to try to quit smoking * Not participating in another smoking cessation trial * Age 18 or older * Speak English Exclusion Criteria: * Hearing impaired * Deemed too sick to participate * Evidence of unstable cognitive or mental health problems who cannot properly provide consent

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Conditions

The condition(s) this trial relates to.

agnosia cancer Pain Smoking Cessation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Pain Smoking cessation

Contacts and locations

Locations

  • Duke University Health System

    Durham, North Carolina, 27710, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.