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New drug combo shows promise in slowing rare gut cancers

NCT ID NCT01744249

First seen May 06, 2026 · Last updated May 21, 2026 · Updated 4 times

Summary

This study tested whether adding the oral drug axitinib to the standard treatment sandostatin LAR could slow cancer growth in people with advanced neuroendocrine tumors that started outside the pancreas. 256 adults with tumors that had recently grown were randomly assigned to get either the combination or sandostatin alone. The main goal was to see how long the cancer stayed under control.

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Contacts and locations

Locations

  • Azienda Ospedaliera Universitaria di Perugia

    Perugia, 06129, Italy

  • Clatterbridge Cancer Centre

    Bebington, Wirral, CH63 4JY, United Kingdom

  • Complejo Hospitalario Univ A Coruña

    A Coruña, Spain

  • Hospital Alvaro Cunqueiro

    Vigo, Pontevedra, 36312, Spain

  • Hospital Central de Asturias

    Oviedo, Principality of Asturias, Spain

  • Hospital Clara Campal

    Madrid, Spain

  • Hospital Clínico San Carlos

    Madrid, Spain

  • Hospital General Universitario de Valencia

    Valencia, 46014, Spain

  • Hospital Gregorio Marañón

    Madrid, Spain

  • Hospital Marqués de Valdecilla

    Santander, Spain

  • Hospital Univ La Paz

    Madrid, Spain

  • Hospital Univ de Salamanca

    Salamanca, Spain

  • Hospital Universitari Vall d'Hebron

    Barcelona, Spain

  • Hospital Universitario 12 de Octubre

    Madrid, Spain

  • Hospital Universitario Miguel Servet

    Zaragoza, Spain

  • Hospital Universitario Ramón y Cajal

    Madrid, Spain

  • Hospital Universitario Virgen de la Victoria

    Málaga, Malaga, 29010, Spain

  • Hospital Universitario Virgen del Rocío

    Seville, Spain

  • Hospital Universitario de Burgos

    Burgos, Spain

  • Hospital Virgen de las Nieves

    Granada, Spain

  • Hospital de Donostia

    Donostia / San Sebastian, Spain

  • Hospital universitario de Leon

    León, Spain

  • Institut Català d'Oncologia L'Hospitalet

    L'Hospitalet de Llobregat, Barcelona, Spain

  • MD Anderson Cancer Center

    Madrid, 28033, Spain

  • Marburg Universitätsklinikum Giessen und Marburg GmbH

    Marburg, 35043, Germany

  • Sapienza, Universitá di Roma, Ospedale sant'Andrea

    Rome, 00189, Italy

Conditions

Explore the condition pages connected to this study.