Brain training and nerve stretching could ease chemo nerve damage
NCT ID NCT07712302
First seen Jul 17, 2026 · Last updated Jul 17, 2026
Summary
This study tests whether graded motor imagery—a brain-based therapy involving left/right judgment, imagined movements, and mirror exercises—can relieve nerve pain and improve leg function in cancer patients with chemotherapy-induced peripheral neuropathy. Half the participants will also receive neural mobilization, a technique that gently moves nerves to improve their flexibility. The goal is to see if adding nerve mobilization boosts the benefits of motor imagery alone.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- graded motor imagery and neural mobilization
- What this could lead to
- If it works, this could offer a drug-free way to reduce nerve pain and improve leg function in cancer patients after chemotherapy.
- What could go wrong
- This is a small, early-stage trial with only 48 participants, so results may not apply to everyone. The therapies are non-invasive but may not work for all types of nerve damage.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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48 people
The number who actually took part.
- Started
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Mar 2025
- Finished
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Jun 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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31 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Both male and female * Age ranging from 31 to 65 years * Diagnosed cancer patients (stage 1 to 3, cancer of any kind) * Chemotherapy sessions (antineoplastic drugs) - at least 1 session * Presence of glove and stocking peripheral neuropathy * LANSS score greater than 12 * Agreed to give complete follow-up Exclusion Criteria: * Any co-morbid conditions that can cause peripheral neuropathy e.g. diabetes, chronic kidney failure * Any trauma history that can cause peripheral neuropathic symptoms * Pre-existing nerve entrapment syndromes * Diagnosed stage 4 cancer patients * Cancer patients taking palliative chemotherapy
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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The University of Faisalabad
Faisalābad, Punjab Province, 38000, Pakistan
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