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Brain training and nerve stretching could ease chemo nerve damage

NCT ID NCT07712302

Symptom relief Sponsor: University of Faisalabad Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 17, 2026 · Last updated Jul 17, 2026

Summary

This study tests whether graded motor imagery—a brain-based therapy involving left/right judgment, imagined movements, and mirror exercises—can relieve nerve pain and improve leg function in cancer patients with chemotherapy-induced peripheral neuropathy. Half the participants will also receive neural mobilization, a technique that gently moves nerves to improve their flexibility. The goal is to see if adding nerve mobilization boosts the benefits of motor imagery alone.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
graded motor imagery and neural mobilization
What this could lead to
If it works, this could offer a drug-free way to reduce nerve pain and improve leg function in cancer patients after chemotherapy.
What could go wrong
This is a small, early-stage trial with only 48 participants, so results may not apply to everyone. The therapies are non-invasive but may not work for all types of nerve damage.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

48 people

The number who actually took part.

Started

Mar 2025

Finished

Jun 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

31 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Both male and female * Age ranging from 31 to 65 years * Diagnosed cancer patients (stage 1 to 3, cancer of any kind) * Chemotherapy sessions (antineoplastic drugs) - at least 1 session * Presence of glove and stocking peripheral neuropathy * LANSS score greater than 12 * Agreed to give complete follow-up Exclusion Criteria: * Any co-morbid conditions that can cause peripheral neuropathy e.g. diabetes, chronic kidney failure * Any trauma history that can cause peripheral neuropathic symptoms * Pre-existing nerve entrapment syndromes * Diagnosed stage 4 cancer patients * Cancer patients taking palliative chemotherapy

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Conditions

The condition(s) this trial relates to.

Ataxia cancer chemotherapy-induced neuropathy neoplasm neuralgia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cancer Chemotherapy-induced peripheral neuropathy (CIPN)

Contacts and locations

Locations

  • The University of Faisalabad

    Faisalābad, Punjab Province, 38000, Pakistan

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