HYPERTENSION

This study tested a lifestyle program designed for Native Hawaiian and Pacific Islander adults with conditions like diabetes, high blood pressure, and obesity. Community health workers delivered the program, which included support for social needs like housing and food access. Th…

This study tested whether a special blood pressure cuff and remote monitoring program can help people with high blood pressure get better control when seeing doctors virtually. About 100 adults with hypertension joined the study. The program tracked blood pressure at home and sha…

This study looked at the safety and effectiveness of azilsartan, a blood pressure medicine, in children aged 6 to 15 with hypertension. Five children took the drug once daily for up to 12 months. Doctors monitored side effects and blood pressure changes. The goal was to see how w…

This study tested a digital program that combines personalized health coaching with a connected blood pressure cuff, all accessible via smartphone or website, to help people with high blood pressure. The goal was to see if this approach improves blood pressure control better than…

This study tested whether using mobile monitoring devices along with nurse support can help people better manage type 2 diabetes and high blood pressure. 220 adults with poorly controlled diabetes and hypertension took part. Researchers measured changes in blood sugar and blood p…

This study looked at whether playing recreational beach tennis for 12 weeks could lower blood pressure and improve physical fitness in people with high blood pressure. 42 adults with hypertension who were not already exercising took part. The results will show if this fun activit…

This study looked at whether a DASH-style diet (modified for diabetes) combined with lower salt intake can lower blood pressure in adults with type 2 diabetes and high blood pressure. 105 participants were fed different diets for 5-week periods. The main goal was to see if the DA…

This study tested a new way to manage both HIV and high blood pressure together in Botswana. Over 4,600 adults with HIV and high blood pressure took part. The goal was to see if combining care helps more people get their blood pressure under control. If it works, this approach co…

This study tested a new drug called lorundrostat in 285 adults whose high blood pressure remained uncontrolled despite taking 2 to 5 standard medications. Participants received either lorundrostat or a placebo added to their current regimen. The goal was to see if the drug could …

This study looked at whether keeping blood pressure very well controlled could prevent bone damage (osteonecrosis) in children and young adults being treated for leukemia or lymphoma. About 50 participants were randomly assigned to either intensive blood pressure control or stand…

This study tested a new drug called lorundrostat in 1083 adults whose high blood pressure was not controlled despite taking 2 to 5 different medications. The goal was to see if adding lorundrostat could safely lower blood pressure more than a placebo. Participants took either the…

This study compared two blood pressure medicines—eplerenone and chlorthalidone—in 79 adults with obesity and high blood pressure or metabolic syndrome. The goal was to see if eplerenone could improve blood flow to the heart and reduce scarring, beyond just lowering blood pressure…

This study tested whether an educational worksheet plus health coaching could help people with chronic kidney disease and high blood pressure lower their blood pressure. 320 adults with moderate to severe kidney disease took part. The goal was to see if this approach improves blo…

This study tested whether a personalized lifestyle program could help adults with insulin resistance, obesity, diabetes, or related conditions improve their metabolic health. Forty participants first received either nutrition or exercise counseling. Those who didn't improve after…

This study tested whether a special diet made from tartary buckwheat can help lower blood pressure in people with mild hypertension. Researchers believe the diet works by restoring healthy gut bacteria. The study involved 130 adults aged 18–60 with untreated grade 1 hypertension.…

This study tested a smartphone app called USeeBP to help African American adults with poorly controlled high blood pressure. 31 participants used the app alongside their usual care. The goal was to see if the app could improve home blood pressure readings and medication adherence…

This study tested a program called ENACTS to help Native Hawaiian and Pacific Islander adults with high blood pressure or type 2 diabetes. The program focused on healthy eating, exercise, and family support. 182 people took part, and researchers measured changes in blood pressure…

This study tested whether trained female community health volunteers (FCHVs) can help prevent and control high blood pressure in rural Nepal. 520 adults aged 30-75 with high blood pressure took part. The volunteers led group meetings for blood pressure checks, health education, a…

This study tested a non-invasive device that gently stimulates a nerve in the ear to see if it can help control blood pressure during heart stent surgery. 480 adults with coronary artery disease and high blood pressure were randomly assigned to receive either the real stimulation…

This study tested a low-cost approach to help clinics in Mozambique better diagnose and manage high blood pressure in people with HIV. Researchers worked with 18 health facilities to improve screening, treatment, and follow-up. The goal was to increase the number of patients with…

This study looked at two common blood pressure medicines—calcium channel blockers and beta-blockers—in people with heart failure with preserved ejection fraction (HFpEF) and high blood pressure. The goal was to see which one better controls blood pressure and helps heart function…

This study looked at whether a personalized food-as-medicine program could help adults who have high blood pressure and struggle to afford enough food. Over 12 weeks, 159 participants received tailored support to improve their diet. Researchers measured changes in blood pressure …

This study tested whether a tablet app used by community health workers could improve the detection and management of anemia, gestational diabetes, and high blood pressure in over 3,400 pregnant women in rural India. Women in the intervention group were screened at multiple point…

This study tested a comprehensive intelligent system (CHESS) to help manage high blood pressure in primary care clinics. Over 1,600 participants were involved, and the system aimed to lower blood pressure over 12 months. The approach used existing clinic tools and medications to …

This study tested a single pill containing three medicines (telmisartan, amlodipine, and rosuvastatin) in 252 Korean adults with both high blood pressure and high cholesterol. After 8 weeks, the pill safely lowered both blood pressure and LDL (bad) cholesterol. People with very h…

This study tested a mobile app called Collabree to help people over 50 with high blood pressure take their medication as prescribed. 144 participants were split into three groups: two used the app and one did not. The goal was to see if the app improved how regularly they took th…

This study tested a program to help African American and Latinx patients with high blood pressure get it under control. 445 participants used home blood pressure cuffs and received support to lower their readings. The goal was to reduce the racial gap in hypertension and improve …

This study tested two different blood pressure treatments in 59 adults under 60 who were newly diagnosed with mild to moderate hypertension. One group took bisoprolol alone, while the other took a combination of valsartan and amlodipine. Researchers used 24-hour monitors to check…

This study tested whether a grape seed extract supplement (Enovita®) can help lower blood pressure in adults with elevated blood pressure or stage 1 hypertension. Eighty adults took either the supplement or a placebo daily for 8 weeks. Researchers measured changes in blood pressu…

This study looked at whether it is safe and helpful to reduce blood pressure medications in frail older adults living in long-term care. Over 500 participants with low blood pressure were randomly assigned to either have their medications slowly reduced or to continue usual care.…

This study looked at whether adding a muscle relaxation technique to aerobic exercise helps people with early-stage high blood pressure more than exercise alone. Forty adults aged 18-45 with stage 1 hypertension took part. The researchers measured blood pressure, heart rate, brea…

This study looked at whether advanced practice nurses (APNs) can improve blood pressure control in adults with high blood pressure. About 483 patients were followed to see if working with an APN helped them manage their condition better than standard care. The goal was to help pa…

This study tested a 4-month program where community health workers provided nutrition education and support to 60 primary care patients with high blood pressure and food insecurity. The goal was to see if adding nutrition help to existing blood pressure coaching was feasible and …

This study looked at how to best manage high blood pressure in people living with HIV in Uganda. Researchers compared two different approaches to add blood pressure care into regular HIV clinic visits. Over 87,000 adults took part, and the goal was to see which method worked bett…

This study tested whether minocycline, an inexpensive antibiotic already approved for other uses, can lower blood pressure in people whose hypertension does not respond to standard medications. Researchers enrolled 34 adults with resistant hypertension and gave them different dos…

This study tested whether bringing HIV and chronic disease care into the community and linking it with microfinance groups helps people with HIV stay in care and keep the virus under control. About 1,200 adults in rural Kenya took part. The goal was to see if this combined approa…

This study tested a new program called Walk Together that helps African American adults with high blood pressure and their family members work as a team to manage the condition. The program was designed to be used in primary care settings. The study included 62 participants and f…

This study looked at whether community health workers (CHWs) can improve health outcomes for people with chronic conditions like diabetes, high blood pressure, and obesity. Over 10 months, 202 low-income adults from specific zip codes received either CHW support plus standard car…

This study looked at two different ways to help people with high blood pressure exercise at home using technology. One group did exercises with a physiotherapist watching and guiding them live through video calls. The other group followed pre-recorded exercise videos on their own…

This study tested a program where teenagers learn about high blood pressure and then teach an adult they know. The goal was to see if this approach could help adults lower their blood pressure. The study involved 64 pairs of adults with high blood pressure and a teen (ages 14-24)…

This study tested whether giving two drugs together (DWC202206 and DWC202207) is safe and effective for people who have both high blood pressure and high cholesterol. 214 adults aged 19 to 80 took part. The main goals were to see if the combination lowered blood pressure and LDL …

This study tested a new way to help people with two or more long-term health problems like HIV, high blood pressure, diabetes, asthma, or depression. Over 1,800 adults aged 40 and older in South Africa took part. Some clinics used a special decision-support tool and home visits f…

This study tested a blood pressure monitoring system to help older adults (65+) take their hypertension medication as prescribed. 200 participants used the system for 6 months, with one group also getting extra tips. The goal was to see if the system improved medication adherence…

This pilot study tested a lifestyle program for African American women who care for a family member with Alzheimer's or related dementia and also have high blood pressure. The program focused on stress management, healthy eating, and physical activity to help lower blood pressure…

This study tested whether 10 weeks of moderate or intense exercise could improve overall brain health and lower blood pressure in adults aged 35-65 with hypertension and a BMI of 25 or higher. Participants used smartphone apps to track workouts and had their brain care score, blo…

This study tested whether a peanut-based food supplement, taken daily for 12 weeks, could improve nutrition and health in adults aged 60 and older living in peri-urban Ghana. 81 participants were randomly assigned to either receive the supplement or continue their usual diet. Res…

This study tested whether taking two blood pressure medicines together works better than taking just one for people with heart disease caused by high blood pressure. 118 adults aged 18-70 took either a combination of valsartan and hydrochlorothiazide or valsartan alone for 8 week…

This study tested whether text messages can help homeless adults with uncontrolled high blood pressure lower their numbers and stay on track with medications and doctor visits. About 120 participants were split into two groups: one got standard healthy-living texts, the other got…

This study tested whether extra nurse-led education and follow-up, including a caregiver, helps stroke patients with high blood pressure control better than usual care. About 290 patients over 60 who had a first stroke and high blood pressure took part. The main goal was to see i…

This study tested whether giving households a low-sodium salt substitute (with potassium replacing some sodium) through community health workers could lower blood pressure. About 618 adults in rural Bangladesh took part. The goal was to see if this simple dietary swap could reduc…

This study tested an experimental drug called ALN-AGT01 in 394 adults with mild-to-moderate high blood pressure. The goal was to see if it safely lowers blood pressure over three months compared to a placebo. Participants did not take other blood pressure medicines during the stu…

This study tested whether a stricter blood pressure target (below 135/85 mmHg) is better than usual care (below 150/100 mmHg) for women who had high blood pressure during pregnancy. 61 women were enrolled shortly after delivery and followed for six months. The goal was to see if …

This study tested a culturally-tailored program that combines nutrition, exercise, and stress management to help African American women improve their heart health. 175 women with risk factors like high blood pressure or prediabetes took part. The goal was to see if the program co…

This study compared two educational programs designed to help Hispanic adults with uncontrolled high blood pressure stick to their medication routine. Over 500 participants took part, and researchers measured how well they took their pills using special bottle caps that record ea…

This study looked at whether community health workers (CHWs) can help adults who have high blood pressure and struggle to afford enough food. 75 participants received support to eat more fruits and vegetables and manage their blood pressure. The goal was to see if this approach i…

This study looked at whether visits from a parish nurse can help people with high blood pressure get it under control. About 100 adults from church health fairs in Los Angeles took part. Half were assigned to see a parish nurse, and the other half went to their regular doctor. Af…

This study tested whether a special exercise program could help people with high blood pressure (hypertension) who have a dangerous nighttime blood pressure pattern. 198 participants were split into two groups: one received the exercise program plus usual care, the other only usu…

This pilot study tested two health coaching strategies for Black adults with stage 1 obesity and conditions like high blood pressure, prediabetes, or high cholesterol. One strategy focused on weight loss, while the other focused on increasing physical activity without targeting w…

This study looked at whether combining high-intensity interval training (short bursts of intense exercise) with the DASH diet (a heart-healthy eating plan) can reduce artery stiffness in people with high blood pressure. Twenty adults with controlled high blood pressure participat…

This study tested whether giving people home blood pressure monitors and digital tools (like texting and online portals) helps them better manage their high blood pressure. 540 adults with uncontrolled hypertension took part. The goal was to see if these tools improve blood press…

This study tested whether community health workers and home blood pressure monitors could help adults in rural South Africa better control their blood pressure. 774 people with high blood pressure took part. The goal was to find the best way to manage this condition long-term.

This study tested a new drug, SLx-2101, in 38 adults with moderate to severe high blood pressure. Participants took either 5 mg or 10 mg of the drug once a day for 14 days. The goal was to see if it safely lowers blood pressure and heart rate. The trial was a small, early-phase s…

This study tested a nurse-led program to help veterans with HIV lower their blood pressure and reduce their risk of heart disease. About 305 veterans took part, receiving either the nurse-led program or standard education. The program used video calls and care coordination to mon…

This study tested whether empagliflozin, a diabetes medication, lowers blood pressure more than other oral diabetes drugs in people with type 2 diabetes and high blood pressure. 300 adults took either empagliflozin or another diabetes pill for 12 weeks. Researchers measured blood…

This study tested whether a single pill containing three medicines (ezetimibe, rosuvastatin, and amlodipine) can safely lower both cholesterol and blood pressure in Korean adults with high blood pressure and high cholesterol. 163 participants were randomly assigned to receive eit…

This study tested a daily pill called lorundrostat in 48 adults with moderate-to-severe sleep apnea and high blood pressure. The goal was to see if the drug could reduce breathing pauses during sleep and lower nighttime blood pressure. Participants were randomly assigned to recei…

This study tested whether adding amlodipine to the blood pressure drug LCZ696 works better than LCZ696 alone. About 718 adults with mild to moderate high blood pressure that wasn't well controlled on LCZ696 took part. The goal was to see if the combination lowered blood pressure …

This study tested whether guiding robotic surgery with the vagus nerve could reduce digestive problems like diarrhea and delayed stomach emptying after spleen removal and blood vessel repair. Sixty adults with cirrhosis, an enlarged spleen, and bleeding from high blood pressure i…

This study tested whether training clinic teams to share tasks (like measuring blood pressure and starting medication) helps people living with HIV get their high blood pressure under control. Over 900 adults from 30 clinics in Nigeria took part. The goal was to see if this team-…

This study looked at whether a drug called bosentan could lower blood pressure in people with sleep apnea as effectively as the standard treatment, CPAP. Nineteen adults with sleep apnea and mild high blood pressure took part. The goal was to see if blocking a certain chemical in…

This study tested an experimental pill called ralinepag for people with pulmonary arterial hypertension (PAH), a serious lung condition that makes the heart work too hard. About 687 adults with PAH took either ralinepag or a placebo on top of their usual treatments. The goal was …

This study tested whether providing free, culturally tailored healthy meals (14 per week for 10 weeks) plus weekly group support sessions could help Black adults with high blood pressure, type 2 diabetes, obesity, or metabolic syndrome. 75 participants were split into three group…

This study tested whether doing wall squats (a type of isometric exercise) can help lower blood pressure in 50 Chinese adults with hypertension who are not very active. Participants were randomly assigned to either a wall squat program or a stretching routine for 24 weeks. The ma…

This study looked at whether the drug sacubitril/valsartan can stop atrial fibrillation (an irregular heartbeat) from returning after a catheter ablation procedure in older adults with high blood pressure. About 320 people aged 55-80 took either the study drug or a standard blood…

This study tested whether adding a second drug (DWC202314) to an existing one (DWC202404) helps lower blood pressure in people whose hypertension is not well controlled with the first drug alone. 192 adults with essential hypertension took part. The main goal was to see how much …

This study tested whether remote blood pressure monitoring helps cancer patients on a drug called bevacizumab better manage high blood pressure. Twenty adults participated, using either a remote device or a logbook to track their readings. The goal was to see if remote monitoring…

This study looked at whether help from a spouse, family member, or close friend can improve how well people with high blood pressure follow their medication and healthy lifestyle plans. 133 people with high blood pressure and their significant others took part. The researchers co…

This study tested an experimental drug called zilebesiran in 375 adults with high cardiovascular risk and high blood pressure that wasn't well controlled by their current medications. Participants received zilebesiran or a placebo added to their usual pills. The main goal was to …

This study looked at whether people with uncontrolled high blood pressure could lower their numbers by monitoring their blood pressure at home. 70 adults with hypertension were split into two groups: one group used a home monitor for 5 days each month, while the other group recei…

This study tested an experimental drug called zilebesiran in 663 adults whose high blood pressure was not well controlled by standard medications. Participants took zilebesiran or a placebo alongside their usual blood pressure pills. The goal was to see if adding zilebesiran coul…

This study tested a new drug, SLx-2101, in 26 adults with moderate to severe high blood pressure. Participants took the drug once daily for up to 14 days to find the best dose and see how it affects blood pressure. The goal was to check safety and how well the drug lowers blood p…

This study tested a program where community health workers provided counseling, doctor visits, and phone calls to help people with both HIV and high blood pressure control their blood pressure. 100 participants in northern Tanzania took part over 6 months. The goal was to see if …

This study tested an experimental drug called KBP-5074 in 162 people with moderate-to-severe chronic kidney disease whose high blood pressure was not well controlled. The goal was to see if the drug could safely lower blood pressure and reduce kidney damage. Participants were ran…

This study tested a virtual health program for African immigrants aged 25-75 who are uninsured and have at least two risk factors like high blood pressure, prediabetes, or obesity. Participants used Bluetooth scales and blood pressure monitors to track their health over six month…

This study tested a procedure called renal denervation, which uses energy to calm overactive nerves in the kidneys, to see if it can safely lower blood pressure in people whose hypertension is not controlled by up to three medications. The study involved 337 participants and meas…

This study tested whether adding a very low-carbohydrate diet to a proven lifestyle program could help lower blood pressure in lower-income African American adults. About 64 participants were followed for 10 months. The goal was to see if this approach could reduce heart disease …

This study tested a smartphone app called SMART-HABITS in 47 adults with chronic kidney disease and high blood pressure. The app provided reminders, feedback, and educational resources to help patients track their blood pressure and steps. The goal was to see if people would use …

This study tested a new way to treat high blood pressure without pills. Doctors used focused ultrasound to modify fat around the kidney in 79 patients with mild hypertension who were not on medication. The goal was to see if this procedure could safely lower blood pressure compar…

This study looked at whether adding community health workers to regular care helps patients with type 2 diabetes and high blood pressure in rural Mexico. 168 adults took part. The goal was to see if their blood sugar and blood pressure improved and if they took their daily medici…

This study tested whether a smartphone app called LowSalt4Life helps people with high blood pressure eat less salt and lower their blood pressure. About 410 adults with high blood pressure used the app, with some getting extra reminders and tips. The goal was to see if the app ma…

This study tested whether giving Black adults with high blood pressure free produce, personalized dietitian coaching, and resource referrals could help them eat a heart-healthy DASH diet. 80 participants were split into two groups to see if the program was practical and improved …

This study tested a monthly injection called tonlamarsen in 206 adults whose blood pressure remained high despite taking at least two medications. The goal was to see if the drug could safely lower blood pressure by targeting a protein involved in blood pressure regulation. Parti…

This study tested whether providing medically tailored meals, grocery vouchers, or a combination can improve health in low-resource families. 56 adults and children with food insecurity and conditions like type 2 diabetes or high blood pressure took part. Researchers measured cha…

This study tested whether a mobile app called Collabree helps people with high blood pressure take their daily pills more consistently. 181 adults in Switzerland who took at least 4 blood pressure pills a day participated. Participants were split into three groups, with two group…

This study tested how often people with high blood pressure need to do isometric (static) exercises to lower their blood pressure. Thirty adults who were not on medication did these exercises once, twice, or three times per week. The goal was to find the smallest effective dose t…

This study tested whether an automatic blood pressure machine (WatchBP Office) gives more accurate readings than traditional manual measurement in Chinese adults with high blood pressure. 149 participants had their blood pressure checked using both methods and a 48-hour monitor (…

This study checked how well the Withings BPM Pro 2, an automatic arm blood pressure monitor, measures blood pressure compared to standard methods. About 89 adults with different arm sizes took part. The goal was to see if the device gives accurate readings for everyday use.

This study tested how accurately a Samsung Galaxy smartwatch can measure blood pressure over time. Researchers compared the watch's readings to those from a standard medical device. The study involved 42 healthy volunteers to see if the watch could be a reliable tool for monitori…

This study trained community health workers to screen Black men for early signs of high blood pressure. Participants received lifestyle advice and were linked to doctors and social services. The goal was to prevent hypertension from getting worse. 430 Black men with elevated bloo…

This study tested whether a single low-dose pill containing three blood pressure medicines could prevent another stroke in people who had a brain bleed (intracerebral hemorrhage). Over 1,600 adults with a history of such a bleed and slightly high blood pressure took either the tr…

This study tested whether using nerve blocks with sedation instead of general anesthesia and opioids is safer and provides better pain control for high-risk patients needing an upper leg amputation. The study included 30 adults with conditions like diabetes, heart disease, or lun…

This small study tested whether an 8-week yoga program could help African American adults with high blood pressure lower their blood pressure, reduce stress, and improve memory for taking medications. Eight participants attended weekly yoga classes at a hospital. The study measur…

This study looked at whether adding paced or diaphragmatic breathing to mat Pilates helps people with stage II hypertension feel less stressed and anxious, and improves their heart and lung fitness. Sixty-three adults aged 40 to 50 took part in six weeks of supervised sessions. T…

This study looked at whether taking peppermint oil by mouth can improve heart health in people with mild to moderate high blood pressure. 40 adults aged 18-65 with slightly elevated blood pressure who were not on blood pressure medication took part. The goal was to see if pepperm…

This study looked at how sleep apnea and not getting enough sleep cause daytime sleepiness. Researchers compared two different programs to see which works better to improve alertness during the day. The study included 558 adults with mild-to-moderate sleep apnea who also slept le…

This early-phase study tested a new way to deliver nitric oxide—a molecule that relaxes blood vessels—by placing a mixture under the tongue. Fourteen healthy adults took part to see if this method safely lowers blood pressure. The goal is to find an alternative to current nitrate…

This study looked at whether giving magnesium sulfate, fentanyl, or both before placing a breathing tube can prevent sudden rises in blood pressure and heart rate in patients aged 50 and older. 76 people having planned surgery took part. The goal was to find a safer way to manage…

This study tested a program that sends text reminders and uses social support and game-like features to encourage people with chronic kidney disease, diabetes, and high blood pressure to check their blood pressure regularly. 70 adults from a University of Pennsylvania kidney clin…

This study looked at whether eating dark chocolate can lower blood pressure and a heart-related chemical in the blood. Fifty-three men with high blood pressure ate either dark chocolate or white chocolate every day for two weeks, then switched. The goal was to see if the compound…

This study compared two types of nerve blocks (ESPB and PVB) to see which one provides better pain relief after open kidney surgery. 72 adults aged 18-60 participated. The goal was to find the best way to reduce pain, use less opioid medication, and help patients recover faster.

This study tested a personalized home exercise program for 34 cancer survivors who also had diabetes or high blood pressure. Participants chose from four exercise options (like walking or yoga) and used a wearable device to track their heart rate. The goal was to see if the progr…

This study looked at whether exercising in the morning or early evening makes a difference in blood pressure and blood vessel health for postmenopausal women with high blood pressure. 68 women aged 55-80 who were not already very active took part. The goal was to see if timing ex…

This study looked at whether a medicine called dexmedetomidine can keep blood pressure and heart rate stable when a breathing tube is placed in people with controlled high blood pressure. 70 adults having planned surgery under general anesthesia took part. The goal was to see if …

This study tested whether a 5-minute calming virtual reality (VR) experience could reduce blood pressure and anxiety in adults with suspected white coat hypertension (high blood pressure only in the doctor's office). 79 participants had their blood pressure and anxiety measured b…

This study tested whether combining grocery delivery with health coaching helps adults with high blood pressure and limited food access eat a heart-healthy diet. 67 participants received an Instacart+ membership, weekly grocery lists, and coaching via text and video for 4 months.…

This study compared two drugs, lignocaine and dexmedetomidine, given through a vein to prevent sudden rises in heart rate and blood pressure when a breathing tube is inserted for surgery. The trial involved 62 adults undergoing elective surgery. The goal was to see which drug bet…

This study measured how high-intensity versus low-intensity strength training affects heart rate and blood pressure in 28 people diagnosed with high blood pressure. Researchers monitored heart rate variability and blood pressure over 24 hours after each workout. The goal was to u…

This study looked at whether listening to podcasts can help people with high blood pressure learn how to manage their condition better. 94 adults with high blood pressure took part. Researchers measured how well patients followed their treatment plan and cared for themselves afte…

This study looked at how different ways of doing resistance exercise (like lifting weights) affect the heart and blood vessels of postmenopausal women. Researchers compared women with normal blood pressure to those with high blood pressure. The goal was to understand how exercise…

This study looked at 72 adults with high blood pressure to see if how well the kidneys concentrate urine is related to artery stiffness. Researchers measured urine concentration and used a simple test to check artery stiffness. The goal was to better understand the connections be…

This study looked at how stretchy the skin and blood vessels are in people with Williams syndrome, a genetic condition that can cause heart problems. Researchers measured skin and pulse speed in 43 participants aged 5 to 70. The goal was to learn how these tissues change over tim…

This study looked at 130 adults with chronic kidney disease to see if a kidney protein called uromodulin affects how salt intake influences blood pressure. Researchers measured salt intake through urine tests and tracked blood pressure over 24 hours. The goal was to understand wh…

This study looked at how a single pill that combines two drugs (pitavastatin for cholesterol and valsartan for blood pressure) works compared to taking the two drugs separately. It involved 52 healthy men aged 20-55. The goal was simply to measure drug levels in the body, not to …

This study looked at whether problems with tiny energy factories inside cells (mitochondria) contribute to higher blood pressure and worse blood vessel health in Black adults. Researchers gave 31 middle-aged and older adults a supplement called MitoQ or a placebo for 8 weeks. The…

This completed study looked at how genes, lifestyle, and social factors like stress and neighborhood affect heart disease risk in 670 African American adults. Participants gave blood and urine samples, had heart scans, and answered surveys. The goal was to build a resource to bet…

This study looked at whether a program called COPE helps Navajo people with diabetes and other chronic conditions. The program trains community health workers to support patients and coordinate with doctors. Researchers compared health measures like blood sugar and blood pressure…

This study looked at over 30,000 adults admitted to hospitals in Maryland to understand why some patients wait in the emergency room even after being admitted (called boarding). Researchers wanted to find out which patients are more likely to board, how boarding increases healthc…

This study looked at how the amount of salt in the diet changes the way the diabetes drug ertugliflozin works on blood pressure and kidneys. Overweight adults with type 2 diabetes followed either a low-salt or high-salt diet while taking the drug or a placebo. The goal was to und…

This study tested a new way to help staff at mental health programs provide better care for heart health risks like diabetes, high blood pressure, and high cholesterol. 85 staff and people with serious mental illness took part. The goal was to see if the program improved how staf…

This study looked at 200 patients who had surgery to clear blocked neck arteries. Researchers checked the removed plaque for bacteria and tracked whether certain germs were linked to later problems like stroke or re-blockage. The goal was to learn which bacteria might be risky, n…

This study tested whether a planned awareness program could improve knowledge about preventing hypertensive crises in people diagnosed with high blood pressure. Thirty-five participants completed the program, and their knowledge was measured before and two weeks after. The goal w…

This study looked at whether giving African American adults with high blood pressure early access to genetic testing for APOL1 gene variants (which increase kidney disease risk) helps improve blood pressure control and kidney care. About 6,800 participants were randomly assigned …

This study examined how daytime fasting during Ramadan influences blood pressure patterns in 150 adults, both with and without high blood pressure. Participants wore monitors to track their blood pressure over 24 hours. The goal was to see if fasting changes blood pressure variab…

This study looked at 125 African American adults with high blood pressure to understand how personal strengths and self-care habits influence their health. Researchers measured blood pressure and quality of life over six months. The goal was to find new ways to help people manage…

This study looked at gut tissue from 35 people with and without high blood pressure to see if there are differences in gut cells. Researchers used samples taken during routine colonoscopies and grew mini-guts in the lab to compare gene activity and growth. The goal was to underst…

This study looked at how two different exercise programs affect heart function and blood pressure in men over 45 with high blood pressure and coronary artery disease. Forty participants did either interval training or continuous training, including both aerobic and resistance exe…

This study tested whether a structured phone call from a medical student could encourage people with uncontrolled high blood pressure to bring a home blood pressure log to their next doctor's visit. 170 adults with high blood pressure were randomly assigned to receive the phone c…

This study looked at 49 veterans with early chronic kidney disease (CKD) and high blood pressure. Researchers wanted to see if common water pills (diuretics) could reduce extra fluid in the body and improve heart health and symptoms like fatigue. They measured fluid levels and he…

This study looked at how blood pressure changes over 12 weeks in people with high blood pressure who used a special wristband that checks blood pressure all day and night. About 1,729 adults took part. The goal was to see if the device helps track blood pressure and if people lik…

This small pilot study looked at whether a short exercise program could improve thinking skills and blood vessel health in older adults (ages 55-75) with high blood pressure. Eleven participants completed a supervised exercise routine, and researchers measured changes in fitness,…

This small pilot study looked at whether aprepitant, a drug used for nausea from chemotherapy, can change levels of aldosterone (a hormone that affects blood pressure) in people with type 2 diabetes and high blood pressure. Five participants took either aprepitant or a placebo fo…

This study looked at two methods for assigning care coordinators to older adults (65+) who have heart disease or related risks like diabetes or high blood pressure. The goal was to see which method better prevents emergency room visits and hospital stays. Researchers compared ass…

This study looked at 149 adults with high blood pressure and insomnia to understand how poor sleep might increase heart disease risk. Participants received Cognitive Behavioral Therapy for Insomnia (CBT-I) to improve sleep. Researchers measured changes in nighttime blood pressure…

This study looked at medical records from over 163,000 older adults with high blood pressure to see if one type of blood pressure medication (dihydropyridine calcium channel blockers) was linked to a lower risk of developing dementia compared to another (hydrochlorothiazide). Res…

This study tested whether an AI system (GPT) could teach medical students about managing high blood pressure better than traditional classroom methods. Fifty-two students participated, either using the AI or standard materials. Researchers measured their knowledge with exams and …

This study searched for genetic differences that make some people more likely to develop high blood pressure. Researchers analyzed data from over 8,600 African American and Mexican American participants. The goal was to better understand the genetic causes of this common conditio…

This early-stage study tested whether drinking beetroot juice (rich in natural nitrates) could improve blood vessel stiffness and brain blood flow in 16 adults aged 50-79. Participants were randomly assigned to drink either nitrate-rich or nitrate-free beetroot juice. The goal wa…

This study followed 200 children and young adults who are overweight or have high blood pressure. Researchers collected health information from their medical records to learn how weight affects the heart over time. The goal is to better understand these risks, not to test a new t…

This study looked at whether eating less salt before bed can improve blood pressure and body rhythms in people with obesity. Researchers measured blood pressure, body temperature, and sleep-related hormone changes in 53 adults. The goal was to learn how salt timing affects health…

This study looked at 139 adults with high blood pressure to find out why some people respond better to certain blood pressure drugs than others. Researchers examined factors like genetics, diet, body size, and heart activity. The goal was to gather knowledge that could help perso…

This study tested a computer tool that helps doctors identify social needs—like trouble getting food or housing—in African American patients with chronic diseases such as diabetes or high blood pressure. The tool gave doctors a risk score and suggested referrals to community orga…

This study tested a new, non-invasive laser technique (Laser Doppler Vibrometry) to measure artery stiffness in 100 adults with high blood pressure. The goal was to see if this laser method works as well as the current standard methods. The study did not provide any treatment, on…

This study tested whether training doctors and nurse practitioners to communicate better and reduce bias could help lower blood pressure in patients. About 118 healthcare trainees and their patients from a safety-net hospital took part. The goal was to see if patient blood pressu…

This study aimed to find better ways to manage high blood pressure in people living with HIV in South Africa. Researchers worked with over 4,300 patients and healthcare workers at nine clinics to understand barriers and test a new care approach. The goal was to improve blood pres…

This study tested whether helping people sleep longer and better for 8 weeks could lower their blood pressure during sleep. 66 adults who slept less than 7 hours a night took part. Researchers used a 24-hour blood pressure monitor to measure changes.

This study looked at whether drinking a KETO5 XOGenius beverage every day could improve markers of heart health, blood pressure, cholesterol, and thinking skills. Six healthy adults aged 18 to 50 took part. The goal was to see if the drink might lower risks for heart disease and …

This study looked at whether small differences in genes related to the apelin system (which helps control blood pressure) are linked to a higher risk of coronary artery disease and high blood pressure. Researchers analyzed blood samples from 223 Syrian patients, comparing those w…

This study reviewed medical records of 901 infants who had surgery for aortic coarctation (a narrowed heart artery) before age one. Researchers wanted to find out how many later developed high blood pressure or re-narrowing of the artery. The goal is to better understand these lo…

This study looked at medical records from over 155,000 older adults with high blood pressure to see if two common diuretics, amiloride and triamterene, affect the risk of developing dementia or Alzheimer's disease. Researchers analyzed data from Medicare claims between 2008 and 2…

This early-stage study tested a new drug called HL1113 in 37 healthy adults to see how the body processes it. The drug is designed to treat high blood pressure and type 2 diabetes. Participants took the drug once and had their blood levels measured to compare the effects of takin…

This study looked at 51 people to understand why those with a rare genetic condition called POR deficiency often develop high blood pressure and blood vessel damage. Researchers compared blood pressure patterns and specific blood markers between patients and healthy volunteers. T…

This study tested whether using a more accurate blood pressure reading from the aorta (central BP) instead of the usual arm cuff helps manage hypertension in people with advanced chronic kidney disease. 116 participants were randomly assigned to either central or standard BP targ…

This study looked at whether having new mothers check their blood pressure at home for 3 weeks after leaving the hospital can help find and manage high blood pressure early. Over 1,600 women took part. The goal was to see if home monitoring is practical and acceptable, and if it …

This study tested a web-based decision support tool to help primary care doctors in rural clinics better identify and manage high blood pressure in children aged 6-17. Over 41,000 children from 45 clinics in three Midwestern states took part. The goal was to see if the tool impro…

This study looked at 10 men to understand why androgen deprivation therapy (ADT) for prostate cancer can lead to high blood pressure. Researchers checked if problems with the nervous system or kidneys were to blame. The goal is to find ways to prevent heart disease in prostate ca…

This study looked at health records from over 800,000 older adults to see if certain blood pressure medicines (propranolol or carvedilol) might lower the risk of developing dementia or Alzheimer's compared to other similar drugs. The goal was to find new uses for existing medicat…

This study looked at the gut bacteria of 192 adults, including those with untreated high blood pressure, those on medication, and healthy people. Researchers compared stool samples to find which bacteria are different in people with hypertension. The goal is to uncover patterns t…

This study looked at whether taking a synbiotic (a mix of probiotics and prebiotics) for 30 days could improve gut health, weight, and heart health in 47 healthy adults aged 18-60. Participants were randomly assigned to receive either the supplement or a placebo. The goal was to …

This pilot study tested whether giving people small cash rewards each week (instead of a lump sum at the end) would encourage them to check their blood pressure at home more regularly. Fifty adults with uncontrolled high blood pressure from community health centers took part for …

This study looked at existing data from over 1,600 African Americans aged 30-55 with severe high blood pressure. Researchers examined genetic, behavioral, and social factors to better understand why this group is more affected. No new participants were enrolled; the goal was to l…

This study looked at how well different blood pressure medicines work in people of White, Black, and South Asian backgrounds. About 940 adults aged 18 to 65 took part. The goal was to see if treatment responses vary by ethnicity, which could help doctors choose the right drug for…