Can a phone app boost Pill-Taking for high blood pressure?
NCT ID NCT04708756
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether a mobile app called Collabree could help people with high blood pressure take their medication more regularly. 181 adults in Switzerland who took at least 4 blood pressure pills daily participated. They were randomly assigned to use the app or receive standard care, and their medication taking was tracked for 90 days. The goal was to see if the app improved adherence and lowered blood pressure.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Collabree mobile phone application
- What this could lead to
- If it works, this could offer a simple, app-based way to help people with high blood pressure stick to their medication routine and improve blood pressure control.
- What could go wrong
- This is a small, completed study with 181 participants, so results may not apply to everyone. The app's effectiveness depends on consistent smartphone use, and it does not replace standard medical care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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181 people
The number who actually took part.
- Started
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Jul 2021
- Finished
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Feb 2025
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Informed consent as documented by signature 2. Over 18 years of age at date of randomization 3. Primary or secondary arterial hypertension 4. Patient in an outpatient clinical setting 5. Prescribed a therapy consisting of 4 or more tablets taken per day 6. Stable medication regime that patient has been taking for at least 4 weeks 7. Participant administers their own medications 8. Participant owns a smartphone with a data plan or constant internet access during the study visits and at home to use the application 9. Minimal required smartphone operating system is iOS 12 and Android 8 (Oreo) 10. Adequate communication in German or Swiss-German (all study documentation will only be set to the German language). Exclusion Criteria: 1. Cognitive impairment that limits ability to understand and complete questionnaires 2. Ongoing evaluation for secondary forms of hypertension 3. 3\. Changes in the participant's medication treatment plan after the baseline visit during the intervention period, unless due to a diagnosis of symptomatic hypotension (in-clinic blood pressure below 110/60 mmHg and symptoms of orthostasis or dizziness) or stage 2 hypertension (in-clinic blood pressure \> 160/100 mmHg); after the endpoint (day 90) visit, a change in the treatment plan will be permitted 4. Uncontrolled hypertension (in-clinic blood pressure \> 180/110 mmHg) 5. Inability to operate a mobile phone and the Collabree application 6. Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, etc. 7. Pregnancy or intention to become pregnant in next 6 months 8. Enrollment of the Sponsor or Investigator, their family members, employees and other dependent persons 9. Participation in another clinical trial 10. Physician-estimated life expectancy of less than 6 months
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University Hospital Basel
Basel, Basel, 4031, Switzerland
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