HYPERTENSION

This study aims to find out if patients who continue taking their GLP-1 weight loss and diabetes medications (like Wegovy or Ozempic) after bariatric surgery have better results than those who stop. Researchers will compare weight loss, blood sugar control, and other health facto…

This study is testing whether a daily, ready-to-drink nutritional supplement made from peanuts can improve health in elderly adults. For 12 weeks, 80 participants will either receive the supplement or not, while researchers track changes in weight, handgrip strength, blood pressu…

This study is testing whether a more interactive version of a smartphone app helps people follow their care plan better after weight-loss (bariatric) surgery. Researchers will compare the new app version to the standard one in 200 patients. They will measure how well patients sti…

This study is testing whether providing home-delivered healthy food kits and virtual cooking classes helps adults with high blood pressure and food insecurity better manage their health. Researchers will compare this program against standard care to see which approach more effect…

This study aims to find the best way to help people control high blood pressure after a stroke to prevent another one. Researchers are comparing two methods: having people monitor their blood pressure at home alone, versus combining home monitoring with virtual group doctor visit…

This study is testing a new support program to help people with high blood pressure take their medications more consistently. It pairs a pharmacist with a community health worker to provide personalized coaching and address common barriers. The goal is to see if this team approac…

This study is testing a 12-week lifestyle program designed for Black women who are breast cancer survivors and have high blood pressure or obesity. The program provides grocery deliveries, cooking classes, and nutrition education. Researchers want to see if this approach is pract…

This pilot study is testing whether providing free boxes of fresh produce helps Veterans with moderate kidney disease and food insecurity. Twenty participants will receive food boxes for six months while researchers track their kidney health, blood pressure, and quality of life. …

This study is testing whether a device that uses ultrasound energy on kidney arteries can help control high blood pressure. Participants with high blood pressure will stop their regular medications for a short period and receive either the real ultrasound treatment or a sham proc…

This study tests whether a peer support program led by community health workers can improve heart health for migrant farmworker women. The program aims to reduce stress and social isolation while helping women access community resources. Researchers will compare this intensive su…

This study is testing if adding a specific type of water pill (a thiazide diuretic) helps lower high blood pressure in people who use peritoneal dialysis for kidney failure. It involves 40 participants who will take the pill for 90 days, then stop for a period, to compare the eff…

This study is testing whether extra support from community health workers can help refugees with high blood pressure take their medications more consistently and better control their condition. Researchers will compare 250 participants who receive this special support program to …

This study is investigating whether restricting daily eating to specific time windows can help people with type 2 diabetes, high blood pressure, and obesity better manage their health. Participants will be assigned to either a daytime eating schedule or a nighttime eating schedul…

This study tests whether a church-based program can help African Americans better manage high blood pressure. Over 300 participants with uncontrolled blood pressure will receive support through Bible studies, healthy eating guidance, and community encouragement. The program aims …

This study is testing whether a personalized digital health program can help people with uncontrolled high blood pressure manage their condition more effectively. The program uses a smartphone app to send customized reminders and support to encourage doctor visits, medication tak…

This study is testing whether receiving home-delivered healthy groceries, chosen with a dietitian's help, can lower blood pressure in adults with high blood pressure. Researchers will compare this approach to giving people a grocery stipend and diet information to shop on their o…

This study is testing a community health program in Kenya that uses trained local peers to deliver blood pressure medications directly to people's homes, supported by mobile health technology. The goal is to see if this approach makes it easier for people to take their medication…

This study aims to observe how well the medication dapagliflozin works for controlling both blood sugar and blood pressure in people with type 2 diabetes and high blood pressure. It will follow 9,000 patients who are already prescribed this medication in their regular care. The g…

This study is testing a 24-week community program designed to improve heart health and reduce stress in Black men who have risk factors like high blood pressure or prediabetes. Participants are randomly assigned to either start the program right away or join a waitlist, and they …

This large study is testing whether adding a new oral drug called vicadrostat to an existing diabetes medicine (empagliflozin) provides better protection against heart and kidney problems in adults who have type 2 diabetes, high blood pressure, and existing heart disease. About 1…

This study is testing whether a smartphone app called a 'Smart Family Doctor,' which uses artificial intelligence, can help people better manage their health after heart procedures. It will involve over 500 adults who have had heart surgery or stents and also have high blood pres…

This study is testing if a short, daily breathing exercise is as good as a standard walking program for lowering high blood pressure in postmenopausal women. Researchers will compare a 5-minute breathing training routine against 150 minutes per week of brisk walking over 3 months…

This study is testing whether a telemedicine system can help people with well-controlled high blood pressure maintain their health as effectively as regular in-person doctor visits. Researchers will compare two groups of 364 participants over 12 months: one using an app for remot…

This study aims to find the ideal length of time for remote blood pressure monitoring after childbirth for mothers who had high blood pressure during pregnancy. Researchers will compare different monitoring durations (from 2 to 6 weeks) to see which leads to the best health outco…

This study is testing if a simpler treatment approach works better for people whose high blood pressure remains high despite taking multiple medications. Researchers are comparing a single pill that combines three common blood pressure drugs against the usual care of taking sever…

This study aims to see if three common types of blood pressure medications affect a person's balance and risk of falling. Researchers will randomly assign 186 adults with newly diagnosed high blood pressure to take one of three different drugs. They will measure participants' bal…

This study is testing whether a special smartphone app can help African-American adults with uncontrolled high blood pressure manage their condition better than standard care alone. About 100 participants will use the app for education and home blood pressure tracking, while rese…

This study aims to create a personalized walking plan to help manage weight and improve heart health. Researchers will recruit 200 overweight or obese adults to first find the link between daily steps, body fat, and health markers. Then, they will test if a custom step goal, base…

This study is testing whether a smartphone app can help older adults who have mild memory problems remember to take their blood pressure medication. Researchers will enroll 100 adults aged 60 and over. Participants will use an app that provides reminders and educational informati…

This study is testing a new digital tool called P3-EX, designed to help doctors create personalized exercise plans for their patients. The researchers want to see if the tool is easy for doctors to use and if patients find it helpful. They will also check if using the tool leads …

This study is testing if a single pill combining two existing drugs works better than either drug alone for people who have both type 2 diabetes and high blood pressure. About 221 participants will take either the combination pill or one of the single drugs for 12 weeks to see wh…

This study is testing whether adding a new investigational drug called zilebesiran to standard blood pressure medications can lower the risk of serious heart problems like heart attack, stroke, or heart failure. It will involve about 11,000 adults with high blood pressure that is…

This study is testing a comprehensive support program to help people better manage multiple chronic conditions like high blood pressure, diabetes, and kidney disease. It involves giving participants home blood pressure monitors and connecting them with a team including community …

This study compares two approaches to help older adults with multiple chronic conditions manage high blood pressure. Researchers will test whether regular home blood pressure monitoring with standard clinic support works better or worse than the same monitoring with additional ph…

This study is testing two different computer decision-support systems to see if they help primary care doctors choose more effective blood pressure medication plans. Over 2,000 adults with high blood pressure across 51 clinics will participate. The computer systems use either sta…

This study is testing a once-daily pill called orforglipron to see if it can safely lower high blood pressure in adults who are also overweight or have obesity. It's a large, late-stage trial comparing the pill to a placebo. The goal is to see if this medication can help control …

This study aims to find the best way to help people with uncontrolled high blood pressure in community health centers that serve diverse, underserved populations. It will compare two approaches: remote blood pressure monitoring alone versus remote monitoring combined with a more …

This study is testing whether trained community health workers can help people in Nepal better manage high blood pressure. Over 3,500 adults with high blood pressure will either receive regular home visits and group meetings from a community worker for a year, or continue with us…

This study is testing whether a smartphone app can help older African Americans better manage their high blood pressure. Researchers want to see if using the app for reminders and support helps people take their medications more consistently and improves their blood pressure read…

This study compares two existing drugs, dotinurad and febuxostat, to see which one better improves artery stiffness in people who have both high uric acid levels and high blood pressure. It will involve 360 adults who meet specific health criteria. Researchers will measure change…

This study is testing whether a medication called iloperidone can help lower blood pressure in people whose hypertension isn't controlled by their current medications. Researchers will compare iloperidone against a placebo in 240 participants over 4 weeks. The goal is to see if t…

This study tests whether a proven blood pressure control program can work when delivered through churches in Chicago's underserved South Side. The program uses community health workers and ministry facilitators to help adults manage their high blood pressure through monitoring, s…

This study is testing whether a dietary supplement made from omega-3 fatty acids can help reduce harmful inflammation in blood vessels. It will involve 50 adults in France who have both obesity and high blood pressure, conditions that increase heart disease risk. Researchers want…

This study is testing if providing free healthy groceries and coaching helps adults with type 2 diabetes and high blood pressure better manage their health. It focuses on people living in Baltimore neighborhoods with limited access to fresh food. Participants are randomly assigne…

This study is testing a new setup method for a special pacemaker that aims to lower high blood pressure. It involves about 30 adults who already need a pacemaker for a slow heart rate and have high blood pressure. Researchers will test different device settings and measure their …

This study is testing whether a mobile phone app can help people who have survived a type of stroke (brain bleed) better control their high blood pressure. 140 stroke survivors will either use the app to track their blood pressure daily and get support calls, or receive their usu…

This study is testing a community-based program to help older African American adults in Houston better control their high blood pressure. It will compare two types of support: one led by pharmacists and another that adds help from community health workers. The goal is to see if …

This study is testing a once-daily pill called orforglipron to see if it can help lower high blood pressure and reduce body weight. It will involve about 487 adults who have both hypertension and are overweight or have obesity. Participants will be randomly assigned to receive ei…

This study is testing whether a structured care program led by community pharmacists can help people with type 2 diabetes manage their condition better than their usual doctor's care. It will involve 600 Albertans whose blood sugar is not yet at a healthy target. The goal is to s…

This study is testing the safety and early effectiveness of a new medical procedure that targets nerves in both the kidney and liver to help lower blood pressure. It is for adults with uncontrolled high blood pressure, including those with other heart or kidney risks. The goal is…

This study is collecting real-world information about an FDA-approved device that treats high blood pressure in people who can't control it with lifestyle changes and medications. The device uses a catheter to deliver ultrasound energy to calm overactive nerves around the kidneys…

This pilot study compares two approaches for treating high blood pressure in young adults who are overweight or obese. Researchers will test whether new weight loss medications (like tirzepatide) can lower blood pressure more effectively than standard treatments that use blood pr…

This Phase 3 trial is testing whether a one-time medical procedure can lower high blood pressure without the need for daily pills. Doctors inject a small amount of alcohol near the kidneys to calm overactive nerves that raise blood pressure. Participants with uncontrolled hyperte…

This study is testing a new combination pill designed to treat two common conditions together: high blood pressure and high cholesterol. It will compare the combination pill to taking the medicines separately. The goal is to see if the single pill is effective at lowering blood p…

This study is testing a community program designed to help Native Hawaiians manage common health conditions like type 2 diabetes, high blood pressure, and high cholesterol. The program combines education on traditional diets and lifestyles with cooking demonstrations. Researchers…

This study is testing whether pairing community health workers with remote blood pressure monitors helps Latinx patients manage high blood pressure better than standard care alone. It will enroll 300 adults who identify as Latinx, have uncontrolled high blood pressure, and strugg…

This study aims to understand how weight-loss surgery helps control health problems linked to severe obesity, such as type 2 diabetes and sleep apnea. Researchers will follow 35 patients who are already scheduled for a specific type of weight-loss surgery (mini-gastric bypass) as…

This study is testing if a time-saving workout using whole-body muscle stimulation (WB-EMS) can help lower resting blood pressure and improve other heart health markers. It will involve 42 adults aged 50+ who have mild high blood pressure and are overweight. The goal is to see if…

This study is testing a new program designed to help people in Africa better manage high blood pressure. It will enroll 800 adults with high blood pressure to see if a bundle of support tools for patients, doctors, and clinics can improve blood pressure control. The goal is to cr…

This study is testing a new, non-surgical treatment for high blood pressure. It uses focused ultrasound waves to target and modify a specific type of fat around the kidneys, which researchers believe plays a role in raising blood pressure. The trial will first find the best treat…

This study is testing whether taking melatonin supplements for 12 weeks helps lower nighttime blood pressure in women going through perimenopause who have high blood pressure. Researchers will compare melatonin to a placebo pill in 70 participants. The goal is to see if this comm…

This study is testing a 6-month remote support program designed to help patients lower their blood pressure and cholesterol. It uses automated messages and a support team to encourage healthy habits and medication use outside of regular doctor visits. The goal is to see if this a…

This study is testing if a new setting for a standard heart pacemaker can help lower blood pressure. It involves 500 people who already need a pacemaker and have high blood pressure. The pacemaker will be programmed with a special feature that is either turned on or off, while al…

This study is testing a once-daily pill called orforglipron to see if it can safely lower high blood pressure and reduce body weight. It will involve about 500 adults who have both hypertension and are overweight or have obesity. Participants will be randomly assigned to receive …

This study aims to see if a medical procedure called renal denervation, when added to standard blood pressure medications, provides better long-term blood pressure control for Medicare patients. Researchers will compare health records from about 1,000 patients who received the pr…

This study is testing whether a gentle, non-invasive shockwave treatment applied to the kidneys can help lower high blood pressure and improve kidney health in people with chronic kidney disease. Thirty patients will be randomly assigned to receive either the real treatment or a …

This study aims to determine which of two common blood pressure medications works better to improve blood flow to the heart muscle and make the heart pump more efficiently. Researchers will compare eplerenone against chlorthalidone in 75 adults who have high blood pressure and a …

This study is testing whether a home device for monitoring a baby's heart rate is practical and acceptable for women with high-risk pregnancies. It aims to see if this remote monitoring can be a helpful addition to regular prenatal care, potentially reducing the need for frequent…

This study is testing whether a smartphone app that gives personalized exercise advice can help people with common health conditions like high blood pressure or high blood sugar become more physically active. About 100 adults in China who are not currently active will use the app…

This study is observing whether an ultrasound treatment called the Recor Paradise System helps control high blood pressure long-term in older adults whose blood pressure remains high despite medication. Researchers will follow 1,000 Medicare-eligible patients to see how well the …

This study is testing if a simple wall squat exercise program can help lower high blood pressure in Chinese adults who don't get enough physical activity. 390 participants with high blood pressure will be randomly assigned to either do wall squats or stretching exercises for 24 w…

This study is investigating whether exercising in the morning or the early evening is more effective for lowering blood pressure and improving blood vessel health. It will involve 79 postmenopausal women aged 55-80 who have high blood pressure. The goal is to see if the time of d…

This study is testing if adding a specially trained 'heart health doula' to standard care helps new mothers recover from pregnancy-related high blood pressure. Researchers will compare two groups: one gets standard home blood pressure monitoring, and the other gets that plus week…

This study is testing if using a comfortable, ring-like device that continuously monitors blood pressure helps doctors manage high blood pressure better than the usual method of checking it during office visits. About 400 adults in Korea whose blood pressure is still high despite…

This study is testing if changing *when* you eat, not *what* you eat, can improve heart health in older adults with high blood pressure. Researchers are enrolling 30 people aged 60+ who typically eat over a 12-hour window. The goal is to see if eating all meals within an 8-hour w…

This study is testing whether a comprehensive village-based management program can help elderly people with chronic heart conditions live longer and healthier lives. The program combines medication, lifestyle changes, education, and regular heart monitoring for up to 10 years. Re…

This study is testing if adding baked potatoes with the skin to a Mediterranean-style diet education can help improve blood sugar control and heart health in adults with prediabetes. Researchers will compare the diet with potatoes to the diet education alone over 12 weeks. They a…

This study is testing a community support program to help adults in Pokhara, Nepal, manage chronic health conditions like high blood pressure, type 2 diabetes, and smoking. It will see if regular home visits from trained local health volunteers, combined with supportive text mess…

This study is testing whether a ketone supplement drink can protect older adults from the negative health effects of eating too much salt. Researchers want to see if the supplement can prevent high salt from raising blood pressure, harming blood vessels, or causing kidney stress.…

This study looks at whether free exercise classes in community parks help older adults improve their health. Researchers will analyze data from 1,000 Miami-Dade County residents aged 50+ who participate in regular park-based fitness sessions. The program includes aerobic exercise…

This study is testing whether empagliflozin, a medication originally for diabetes, can improve heart function in older adults at risk for heart failure. Researchers will give 80 participants either the medication or a placebo pill daily for 9 months to see if it strengthens the h…

This study is testing whether telling people their genetic risk for high blood pressure helps them manage it better. Researchers will enroll 300 adults aged 18-55 who already have high blood pressure and poor heart health. Half will receive their genetic risk score and counseling…

This study tests a new support program for low-income patients with chronic diseases like diabetes and heart problems after they leave the hospital. It provides free medications, delivers them to the bedside and then to the home, and offers a coach to help with follow-up care. Re…

This study is testing a new team-based program to help people better manage their high blood pressure. It will involve 200 African American and Latinx adults from Chicago's West Side who have uncontrolled hypertension. The program provides remote blood pressure monitoring, suppor…

This study is testing if a fast-acting intravenous (IV) drug called clevidipine can control dangerously high blood pressure more quickly and steadily than other standard IV medications in people who have just had a stroke caused by bleeding in the brain. It will enroll 1,000 adul…

This study is testing a new, personalized strategy for managing fluid in veterans on dialysis. It aims to see if using a patient's own recent blood pressure patterns to guide how much fluid is removed is better than the standard approach. The goal is to better control fluid overl…

This study is testing if applying gentle, controlled heat to the abdomen at night can safely lower high blood pressure in people with autonomic failure, a rare nerve disorder. Researchers will compare the effects of real heat versus a sham (fake) treatment in 20 participants. The…

This study is testing if a simple technique called remote ischemic preconditioning (RIPC) can help lower blood pressure in people with mild hypertension. RIPC involves briefly squeezing and releasing the blood flow in an arm with a blood pressure cuff. Researchers will compare th…

This study is testing if a drug called empagliflozin can help prevent heart failure in people who have high blood pressure and are at high risk for heart problems, but do not have diabetes. About 120 participants will be randomly assigned to take either the drug or a placebo pill…

This study is testing whether having a doctor visit patients at home helps manage high blood pressure and type 2 diabetes better than standard clinic visits. Researchers will compare health outcomes for 100 adults who receive two home visits versus those who get usual clinic care…

This study tests two different church-based programs to help reduce heart disease risk in Black adults in New Orleans. It will compare a program led by trained community health workers, which includes coaching and support, to a simpler group education program. The goal is to find…

This study is testing a 24-week lifestyle program called Inspire HER, designed specifically for Black women at risk for heart disease. The program provides health education, physical activity guidance, and social support resources. Researchers will compare the program's effective…

This study is testing if a mindfulness training program delivered over Zoom can help lower high blood pressure in Black women. It will compare the mindfulness program to a general support group to see which is more effective at reducing blood pressure, stress, and depressive symp…

This study aims to see if adding short daily stair climbing to regular brisk walking lowers high blood pressure more effectively than walking alone in inactive adults who are overweight and have hypertension. It will involve 450 participants split into three groups: one combining…

This study is testing whether community health workers, guided by a mobile app and supervised by remote doctors, can manage high blood pressure as effectively as a physician. It involves 460 adults with high blood pressure in rural Guatemala and will last 12-24 months. The goal i…

This study is testing whether drinking beetroot juice, which is rich in natural nitrates, can help lower blood pressure and improve blood flow to the kidneys in people with high blood pressure and early-stage kidney damage. About 20 participants will drink either real beetroot ju…

This early-stage study is testing a new drug called KN060 to see if it can safely lower high blood pressure. About 60 adults with high blood pressure will receive either the drug or a placebo (inactive solution) via an IV drip every two weeks for 12 weeks. Researchers will compar…

This study is testing whether a combination of high-intensity interval training (short, very hard bursts of exercise) and the DASH diet (a diet known to lower blood pressure) can improve artery stiffness in people with high blood pressure. Researchers will recruit 20 adults aged …

This study is testing an experimental drug called QCZ484, given as an injection under the skin every six months, to see if it can safely lower and control high blood pressure. It will involve about 380 adults with mild to moderate hypertension. Researchers will compare different …

This study is testing if a drug called patiromer can help people with moderate to severe chronic kidney disease safely take higher doses of a common kidney-protecting blood pressure medication (irbesartan). In this 44-person trial, participants will try both patiromer and a place…

This study is testing if a specially designed mobile game can motivate Native American adults with high blood pressure to be more physically active. Half of the 220 participants will use the game, which rewards them for steps tracked by a sensor, while the other half will just us…

This study is testing whether a phone-based program that encourages teenagers to sleep longer can help lower their high blood pressure. Researchers are enrolling 10 teens (ages 13-18) who were recently diagnosed with high blood pressure and who get less than 7.5 hours of sleep on…

This study is testing if a faster version of a kidney nerve-calming procedure works as well as the older, longer method to lower high blood pressure. It will involve about 130 adults whose blood pressure remains high despite treatment. Researchers aim to see if simplifying where …

This study is testing whether community cooking classes focused on traditional Native Hawaiian foods can help people better manage diabetes, high blood pressure, and weight. The program involves 1,780 Native Hawaiian adults who will attend quarterly cooking demonstrations and cul…

This study is testing if a new clinic program can help control chronic diseases like high blood pressure, diabetes, and asthma. The program screens patients for social needs like housing or food insecurity and works to reduce racial bias in care. Researchers will enroll 68,000 ad…

This study is testing whether a smartphone app can help people with high blood pressure remember to take their medication every day. Researchers will see if daily reminders, small rewards, or simple planning tips (like linking pill-taking to a morning routine) lead to better medi…

This study aims to reduce heart disease risk for Black women during and after pregnancy. Researchers will compare two support programs for 432 Black mothers with high blood pressure or obesity. One program provides basic health coaching, while the other adds community doula care,…

This study is testing a new, wrist-worn blood pressure monitor (Aktiia) to see if it works as well as a standard home blood pressure cuff. About 35 adults with high blood pressure will wear the wrist monitor for 4 to 19 weeks while also using a cuff. The goal is to see if the con…

This study is testing a new questionnaire designed to quickly and accurately measure how much salt patients with high blood pressure or kidney disease are eating. Researchers will compare the questionnaire results against a 24-hour urine test, which is the gold standard for measu…

This study is testing a new blood test to more accurately find a specific, treatable cause of high blood pressure called primary aldosteronism. Researchers want to see if this new test works well even while people stay on their regular blood pressure pills, avoiding the need to s…

This study is testing a new, cuffless wrist-worn device that measures blood pressure from your radial artery. Researchers will compare its readings to those from a standard arm-cuff monitor in 91 healthy volunteers, some with normal and some with high blood pressure. The goal is …

This study aims to improve the screening test for a specific hormonal cause of high blood pressure, called primary aldosteronism. It will test if taking a single dose of a steroid pill (dexamethasone) the night before a blood test makes the results clearer for patients who are al…

This study is testing whether a ketone supplement drink can protect young adults from the negative health effects of a high-salt diet. Researchers want to see if the drink can prevent high salt from raising blood pressure, harming blood vessels, or causing kidney stress. Healthy …

This study aims to see if providing free healthy prepared meals and nutrition education improves people's diets more than just getting exercise coaching. It will involve 120 adults from Anson County who have or are at risk for chronic conditions like diabetes, heart disease, or o…

This study aims to prevent heart failure in adults at high risk, primarily due to high blood pressure, in Detroit and Cleveland. It uses mobile health units to reach people in their communities and pairs them with community health workers and pharmacists to improve access to care…

This study is testing whether taking low-dose aspirin for six months after giving birth can help women recover from preeclampsia, a serious pregnancy complication. Researchers want to see if aspirin improves blood vessel function and lowers blood pressure in 60 new mothers. The m…

This study is testing a community program that uses team support and expert coaching to help people adopt healthier lifestyles. It aims to prevent high blood pressure in those at risk and help those already diagnosed better manage it. The program focuses on diet, exercise, and ot…

This study tests whether training religious leaders about blood pressure can help lower average blood pressure in their communities. In Tanzania, 20 communities will be involved, with half receiving the training program and half serving as a comparison group. The program teaches …

This large study is testing whether helping older adults (70+) lower their blood pressure more than usual can prevent or slow down memory loss and dementia. It will compare a special support program for blood pressure control against regular medical care in 4,000 people. Research…

This study is testing whether graphic health warnings about smoking, combined with personalized counseling from local pharmacists, can help people quit smoking and lower their blood pressure. It will involve over 5,000 adults in Bangladesh and Pakistan who smoke or have high bloo…

This study is testing whether a digital health coaching program using smartwatch data can help people improve their lifestyle and prevent chronic diseases. It will enroll 1,700 adults in Singapore who are at risk for or already have conditions like high blood pressure, prediabete…

This study is testing whether a combination of a brain-healthy diet and regular exercise can help prevent memory and thinking problems in Black adults who have high blood pressure. Researchers will compare two groups: one receives home-delivered meal kits, cooking classes, and ex…

This study aims to adapt and improve a health program called 'Staying Healthy After Childbirth' (STAC) specifically for Black women and birthing persons. Researchers will work closely with community members and a small group of participants to gather feedback on how to best imple…

This study is testing whether a single dose of beetroot extract can help older women with high blood pressure during exercise. Researchers want to see if the supplement lowers exercise-related blood pressure spikes and improves oxygen delivery to muscles. Twenty women aged 60-70 …

This study is testing a 12-week program designed to help women over 40 who are living with both HIV and high blood pressure. The program combines personalized exercise plans, support from a peer, and home blood pressure monitoring. Researchers want to see if this approach is prac…

This study aims to understand how common undiagnosed sleep problems are in healthy Somali American adults. Researchers will measure participants' sleep patterns and blood pressure over 24 hours to see if poor sleep is linked to higher blood pressure. The goal is to gather knowled…

This study aims to better understand how the body automatically controls blood pressure and heart rate when people stand up or exercise. Researchers will observe 120 healthy adults and adults with high blood pressure, measuring their heart rate and blood pressure during specific …

This study is analyzing data from an existing free afterschool program in Miami parks to see how it affects teens' health and well-being. Researchers will look at data from about 1000 participants, aged 12-17, from underserved neighborhoods. The goal is to understand if the progr…

This study aims to track the long-term health of over 4,000 Shanghai adults to understand how heart, kidney, and metabolic conditions develop and interact over time. Researchers will follow the same group of people originally examined in 2016-2017, checking their health periodica…

This study is creating a collection of health information and DNA samples from 500 adults to help future researchers understand heart disease, high blood pressure, diabetes, and obesity. Participants provide their health history and a blood sample, which will be stored in a bioba…

This study aims to better understand how heart conditions progress over time by having 5,000 adults with cardiovascular disease wear special monitoring devices. Participants will use wearable sensors that track heart rate, breathing, and other measurements while going about their…

This study is testing whether a 12-week education and support program helps hospitalized African American adults with advanced chronic kidney disease. Participants receive education sessions, phone calls, and text messages about managing their condition and planning for future tr…

This study is testing whether nurses using artificial intelligence (AI) tools can provide medical care that's as good as standard doctor visits for common conditions. About 670 adults in rural India with issues like high blood pressure, diabetes, fever, or breathing problems will…

This study is a community partnership, not a treatment trial. Its purpose is to understand how to better involve specific communities in health research and improve health-related behaviors. It will enroll 1,500 adults from specific racial/ethnic groups and regions in Colorado. T…

This study aims to gather detailed health information from 600 active-duty U.S. Army soldiers. Researchers will measure diet, fitness, body composition, blood markers, and mental health to understand how these factors relate to conditions like high blood pressure and diabetes. Th…

This study aims to understand how obesity relates to heart disease risk in Black men and women, as past research shows risk factors may work differently in this population compared to others. Researchers will recruit 2000 healthy, non-diabetic Black adults to measure body fat, bl…

This study aims to understand how a structured approach to managing heart health risks works in everyday doctor's offices. Researchers will observe 220 adults who already have risk factors like high blood pressure or diabetes, but will not change their current treatments. The goa…

This early-phase study is testing a new radioactive tracer called [18F]FNP-59 to see if it can create clear pictures of the adrenal glands using PET/CT scans. The study includes healthy volunteers (some of whom will have their hormones temporarily altered) and people with known a…

This study aims to collect long-term safety and effectiveness data on a procedure that treats high blood pressure by disrupting nerves near the kidneys. It will follow up to 5000 patients from around the world for 1 to 5 years after they receive the procedure as part of their nor…

This study aims to discover the genetic causes of high blood pressure that starts in childhood. Researchers will follow over 2,300 children, adults who had it as kids, and their healthy relatives for up to 10 years, collecting blood, urine, and health data. The goal is to map the…

This study aims to see if a detailed, non-invasive scan of the blood vessels in the back of the eye can reveal information about a person's overall heart and blood vessel health. Researchers will follow 300 people with high blood pressure, diabetes, or high cholesterol for five y…

This large observational study aims to collect real-world information on how patients with type 2 diabetes, high blood pressure, heart failure, and/or chronic kidney disease are currently managed. It will enroll 35,000 adults from many countries to track their treatments, doctor …

This study aims to understand why women who go through menopause early (before age 45) might have higher blood pressure. Researchers will compare the nervous system activity and blood pressure responses of 160 women in different menopause groups. The goal is to gather knowledge a…

This study aims to understand the data from HeartMate 3 heart pumps to see if it can predict medical problems and improve patients' quality of life. Researchers will collect data from 150 adults who have received this specific pump, looking for patterns that might warn of issues …

This study aims to understand how small vessel disease in the brain develops and progresses, which can lead to memory problems and dementia. Researchers will follow 50 people who have had a stroke and have risk factors like high blood pressure or diabetes. Participants will have …

This study aims to understand how weight loss surgery changes the bacteria in your gut and how those changes might improve heart health and diabetes. Researchers will follow 300 patients for up to 10 years after their surgery, collecting blood and stool samples to look for patter…

This study aims to understand how sleep and the body's natural daily rhythms affect blood pressure in people with high blood pressure. Researchers will observe 32 adults with hypertension in both home and controlled lab settings, measuring sleep patterns, heart activity, and stre…

This study aims to understand how chronic diseases like high blood pressure, diabetes, and frailty develop and progress in a rural Chinese county. Researchers will follow 20,000 adult residents for three years, collecting health data and samples to build a detailed picture of com…

This study aims to understand why some Black individuals develop primary aldosteronism, a condition where adrenal gland tumors cause severe high blood pressure. Researchers will examine the genes of 1,150 participants with difficult-to-control blood pressure to identify genetic c…

This study is testing a new type of MRI scan that can take pictures of chemical activity inside the heart. Researchers will give 112 participants, some with high blood pressure or thickened heart muscle, a special injection and then scan their hearts. The goal is to see if this n…

This study aims to understand how nerve activity affects blood sugar and blood pressure in people with obesity. Researchers will give 12 participants different pills (a placebo, a blood pressure drug, or a nerve-blocking drug) for two-week periods to see which one best improves t…

This is an early, exploratory study to test a new imaging tracer called [18F]FNP-59. The goal is to see if it can safely and effectively create pictures of cholesterol movement in the adrenal glands of healthy volunteers. Researchers hope this improved imaging tool will help futu…

This study aims to understand how taking many different medications affects the health of older adults living with chronic diseases like heart disease, diabetes, and high blood pressure. Researchers will follow 2,000 participants aged 65 and older for two years, asking them to co…

This is an early safety study testing a new high blood pressure medication called VB19055 in healthy Chinese adults. Researchers will give different doses to 86 healthy volunteers to check for side effects, see how the drug moves through the body, and test if food affects its abs…

This study aims to understand why some patients have bad reactions to a common combination of eye drops (tropicamide/phenylephrine) used before eye exams and surgery. Researchers will follow 1,000 hospitalized patients, checking their vital signs and asking questions before and a…

This study aims to test new, high-tech eye imaging systems that can see microscopic details of the eye, like individual cells and blood flow, which are not visible with standard equipment. Researchers will enroll 1,200 participants, including people with various eye conditions an…

This early-stage study aims to understand if an experimental drug called angiotensin-(1-7) can improve heart and blood vessel health in people who have both obesity and high blood pressure. Researchers will give the drug or a placebo (saltwater) to 52 participants through an IV a…

This study is observing whether a free, daily after-school program in community parks improves children's health. Researchers will analyze data from about 5,000 kids aged 6-14 who participate in the program, which includes sports, games, and nutrition lessons. The goal is to see …

This study aims to understand how blood flow to muscles is controlled in healthy people and in those with conditions like COPD, heart failure, and high blood pressure. Researchers will measure blood flow in the arms and legs before and after giving specific drugs or having partic…

This study aims to discover the genetic factors that contribute to type 2 diabetes and related conditions like high blood pressure in people of African ancestry, particularly the Yoruba population in Nigeria. Researchers will collect health data and DNA samples from 10,000 partic…

This study is testing whether a new decision-making guide helps hospital doctors better manage chronic medications like those for diabetes and high blood pressure in older patients. Researchers will see if doctors using the guide feel more confident and make fewer unnecessary med…

This is an early-stage study to check the safety and side effects of a new injectable drug called LY3971297. It will involve about 225 healthy adults and adults with obesity, high blood pressure, or reduced kidney function. The main goal is to see how the body handles the drug an…

This study aims to understand the underlying causes of high blood pressure in children and how it damages the heart and kidneys. Researchers will follow 125 children and teens, some with newly diagnosed high blood pressure and some healthy, for two years. They will collect blood …

This early study aims to understand how stimulating nerves near the kidneys affects the body before and after a blood pressure treatment called renal denervation. It will enroll 19 adults with high blood pressure who are already on 1-3 medications. The main goal is to gather safe…

This study aims to understand if the thickness of fat surrounding a donated kidney influences the donor's future kidney function and blood pressure. Researchers will follow 100 living kidney donors for about 6 months after their surgery, measuring their fat, blood pressure, and k…

This study aims to understand the challenges people with rheumatoid arthritis face in controlling their high blood pressure, which increases their risk of heart disease. Researchers will work with 25 participants from the Duke Health System to identify barriers and test a support…