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New shortcut for blood pressure treatment?

NCT ID NCT07115953

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 2 times

Summary

This study tests a faster version of a procedure called renal denervation, which uses energy to calm overactive nerves in the kidneys to lower blood pressure. About 130 adults with uncontrolled high blood pressure will receive the quicker procedure. The goal is to see if it works as well as the standard method while taking less time.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 130 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2025

Expected to finish

Dec 2029

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Individual is diagnosed with hypertension and has a baseline office systolic blood pressure ≥140 mmHg 2. Individual has a baseline office diastolic blood pressure ≥ 90 mmHg 3. Individual has an average systolic baseline home blood pressure ≥135 mmHg (with ≥7 days of valid pre-procedure measurements) 4. Individual has a valid 24-hour Ambulatory Blood Pressure Measurement at baseline Exclusion Criteria: 1. Individual lacks appropriate renal artery anatomy 2. Individual has undergone prior renal denervation 3. Individual has a documented condition that would prohibit or interfere with ability to obtain an accurate blood pressure measurement 4. Individual requires chronic oxygen support or mechanical ventilation other than nocturnal respiratory support for sleep apnea 5. Individual has an estimated glomerular filtration rate (eGFR) of \<45 mL/min/1.73m2 6. Individual has one or more episode(s) of orthostatic hypotension 7. Individual is pregnant, nursing or planning to become pregnant 8. Individual has documented primary pulmonary hypertension 9. Individual has documented type 1 diabetes mellitus or poorly-controlled type 2 diabetes mellitus with glycosylated hemoglobin greater than 8.0%

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    20 sites in 8 countries. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • AZ Sint Jan Brugge-Oostende av

    RECRUITING

    Bruges, 8000, Belgium

  • Algemeen Stedelijk Ziekenhuis - Campus Aalst

    RECRUITING

    Aalst, Belgium

  • CHC MontLégia

    RECRUITING

    Liège, Liège, 4000, Belgium

  • Erasmus University Medical Center

    RECRUITING

    Rotterdam, Netherlands

  • Hippokration General Hospital of Athens

    RECRUITING

    Athens, 11527, Greece

  • Institut Jantung Negara - National Heart Institute

    RECRUITING

    Kuala Lumpur, 50400, Malaysia

  • Leipzig Heart Institute

    RECRUITING

    Leipzig, Germany

  • MacKay Memorial Hospital, Tamsui Branch

    RECRUITING

    Taipei, Taiwan

  • Mater Misericordiae University Hospital

    TERMINATED

    Dublin, Dublin, D07 R2WY, Ireland

  • National Taiwan University Hospital

    RECRUITING

    Taipei, Taiwan

  • Oxford University Hospitals NHS Trust - John Radcliffe Hospital

    RECRUITING

    Oxford, United Kingdom

  • Royal Perth Hospital

    RECRUITING

    Perth, Australia

  • Sana Kliniken Lübeck GmbH

    RECRUITING

    Lübeck, Schleswig-Holstein, 23560, Germany

  • Sarawak Heart Center

    RECRUITING

    Kota, Malaysia

  • Schwarzwald-Baar Klinikum Villingen-Schwenningen

    RECRUITING

    Villingen-Schwenningen, Germany

  • The Alfred Hospital

    RECRUITING

    Melbourne, Australia

  • Universitair Ziekenhuis Gent

    RECRUITING

    Ghent, 9000, Belgium

  • Universitat des Saarlandes

    RECRUITING

    Homburg, Saarland, 66123, Germany

  • Universitätsklinikum Erlangen

    RECRUITING

    Erlangen, Germany

  • Ziekenhuis Oost Limburg

    RECRUITING

    Genk, Limburg, 3600, Belgium

  • Zuyderland Medisch Centrum Heerlen

    RECRUITING

    Heerlen, 6419 PC, Netherlands

More trials for these conditions

Other studies related to the condition(s) this trial covers.