Blood pressure trial aims to stop dementia before it starts
NCT ID NCT05106036
First seen Jan 04, 2026 · Last updated Jun 19, 2026 · Updated 26 times
Summary
This study tests whether helping doctors manage high blood pressure more aggressively can prevent cognitive decline and dementia in adults aged 70 and older. 4,000 participants will be randomly assigned to either a special decision-support tool for their doctors or usual care. The goal is to see if better blood pressure control can keep minds sharp longer.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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UT Southwestern Medical Center
RECRUITINGDallas, Texas, 75390, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Clinical decision support tool and team-based care for blood pressure management
What this could lead to
If successful, this could show that lowering blood pressure in older adults helps prevent memory loss and dementia.
What could go wrong
This is a pragmatic trial testing a care approach, not a new drug. Results may be modest, and cognitive benefits are not guaranteed.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.