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Smart system helps control blood pressure in thousands

NCT ID NCT05605418

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a comprehensive intelligent system (CHESS) to help manage high blood pressure in primary care clinics. Over 1,600 people took part, and the system aimed to lower blood pressure over 12 months. The approach used technology to support doctors and patients in better controlling hypertension.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

1,666 people

The number who actually took part.

Started

Mar 2023

Finished

Oct 2024

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

35 to 79 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria for Sites: 1. An electronic data collection system is routinely used at the clinic for hypertension management in PHC sites, and the distance between sites must be \>2km; 2. At least one drug of each of the five classes of recommended antihypertensive medications is available at the clinic: * A: Angiotensin-converting enzyme inhibitors (ACEI; e.g., captopril or enalapril); * A: Angiotensin receptor blockers (ARB; e.g., losartan or valsartan) * B: β-blockers (e.g., atenolol, metoprolol, or bisoprolol) * C: Calcium antagonists (e.g., nitrendipine, nifedipine, or amlodipine) * D: Diuretics (e.g., hydrochlorothiazide, indapamide, or indapamide SR tablets) 3. Has an outpatient clinic for hypertension treatment and staff are willing to take part in the study. Inclusion Criteria for Participants: 1. Age ≥35 years and \<80 years 2. Local resident of the community/township who attends the PHC clinic for hypertension management, and will not travel for more than 3 months during the study period; 3. Established diagnosis of essential hypertension, with uncontrolled BP before randomization (defined as office BP≥140/90mmHg, and 24-hour ambulatory BP≥130/80mmHg); 4. Own and be able to use a smartphone daily; 5. Be willing to participate in the study and sign the informed consent. Exclusion Criteria for participants: 1. Physician-diagnosed or suspected secondary hypertension (e.g. hypertension caused by renal disease, renal artery stenosis, aortic stenosis, primary aldosteronism, pheochromocytoma/paraganglioma, Cushing's syndrome, thyroid dysfunction, intracranial disease, drug- induced, or rare monogenic genetic disease), or the presence of other structural heart diseases, such as aortic insufficiency, hypertrophic cardiomyopathy, or congenital heart disease; 2. Office or ambulatory SBP≥180 mmHg and/or DBP≥110 mmHg before randomization; 3. Physician-diagnosed atrial fibrillation; 4. Physician-diagnosed CKD, estimated glomerular filtration rate (eGFR) \<60 mL/min/1.73 m2 (if serum creatinine is available), or currently on dialysis treatment; 5. Physician-diagnosed hepatic dysfunction, or ALT≥ 2\*ULN; 6. Currently at the unstable or terminal stage of any disease (e.g. new- onset cardiovascular and cerebrovascular diseases occurred within 3 months, malignant tumors); 7. Intolerance to at least two classes of antihypertensive medications among A, B, C or D; 8. Currently taking 3 or more antihypertensive drugs; 9. The subject is pregnant or breastfeeding, or planning to become pregnant or breastfeeding during the study period; 10. Have communication or cognitive disorders; 11. Be unwilling to take antihypertensive drugs, or assumed poor adherence to treatment; 12. The subject is participating in other clinical trials at the moment.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Fuwai Hospital, Chinese Academy of Medical Sciences, National Center for Cardiovascular Diseases

    Beijing, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.