China National Center For Cardiovascular Diseases

This study tests whether a home-based cardiac rehabilitation program delivered through a mobile app can reduce plaque buildup in the coronary arteries. 176 adults with mild to moderate artery narrowing will be randomly assigned to either the mobile rehab program (including exerci…

This study tests a new way to guide catheter ablation for atrial fibrillation (AF), a common heart rhythm problem. The technique uses unipolar voltage mapping to find specific electrical signals (QS potentials) that may help keep AF going. Researchers will compare this personaliz…

This study tests whether an AI-powered mobile app, called SMART-CHD, can improve outcomes for adults aged 18-45 with premature coronary artery disease after they leave the hospital. Participants use the app and wearable sensors to track their health, receive reminders, and get pe…

This study compares two blood-thinning strategies after a combined heart bypass and endarterectomy procedure. About 202 adults with widespread coronary artery disease will receive either standard dual antiplatelet therapy or that therapy plus warfarin. The goal is to see if addin…

This study tests whether an artificial intelligence (AI) smartphone app can help adults with coronary heart disease exercise safely at home after hospital discharge. About 200 low-risk patients will either use the AI platform with a wristband or receive standard care. The goal is…

This study tests whether artificial intelligence (AI) can help doctors in China pick better blood pressure medications for their patients. Over 2,000 adults with high blood pressure will be treated at primary care clinics. Some clinics will use AI software that considers patient …

This early-stage study tests whether empagliflozin, a drug used for diabetes, can help people with pulmonary arterial hypertension (PAH). About 72 adults will take either the drug or a placebo daily for 12 weeks. Researchers will check if it lowers lung blood pressure and improve…

This study tests whether an AI-powered smartphone app, called 'Smart family doctor,' can help people who have had heart bypass surgery or stents better control their blood pressure, diabetes, and cholesterol. About 536 adults who already have these conditions will use the app to …

This study tests a medicine called ademetionine in 44 adults with a heart condition that blocks blood flow. Participants will take either the medicine or a placebo for 16 weeks. Researchers will check if it helps with exercise, symptoms, and heart function.

This study is testing a smartphone mini-program that gives personalized exercise plans to people with high blood pressure, blood sugar, cholesterol, and uric acid (the 'Four Highs'). Over six months, 100 participants will use the app to see if it helps them walk more and improve …

This study compares a new procedure called pulsed field ablation (PFA) to standard treatment for atrial fibrillation, a common heart rhythm problem that raises stroke risk. About 1,574 adults who need catheter ablation will be randomly assigned to receive PFA or standard care. Th…

This study tests whether a daily pill called engagliflozin (a type of SGLT2 inhibitor) can improve heart function in people who have high blood pressure and early signs of heart failure but do not have diabetes. About 120 adults will receive either the drug or a placebo for 6 mon…

This study tests whether Xuesaitong soft capsules can reduce inflammation (measured by hsCRP levels) in 240 adults with stable coronary heart disease. Participants take the capsule or a placebo for 12 weeks. The goal is to see if this treatment helps control key risk factors for …

This study tests a new surgical method to reduce brain complications, like silent strokes, in people having heart bypass surgery. Researchers will compare the new 'no-touch' technique to standard surgery in 380 adults with blocked heart arteries. The goal is to find a safer way t…

This study tests a new technology called IVUS-FFR that uses ultrasound images from inside heart arteries to quickly check if a blockage is serious enough to need a stent. Unlike the current standard test, it doesn't require an extra pressure wire or medication that can cause disc…

This study tests whether an AI algorithm that analyzes facial images can effectively screen for coronary artery disease (CAD) in high-risk community adults (those with diabetes, high blood pressure, or over 65). About 1,392 participants will have their photo taken and then underg…

This study tests whether two traditional Chinese medicines—Compound Danshen Dripping Pills and Qishen Yiqi Dripping Pills—can reduce chest pain and improve quality of life in elderly patients (75-90 years old) with coronary heart disease who still have symptoms despite standard t…

This study looks at recovery after heart surgery for people with complex congenital heart disease (CCHD). Researchers will analyze medical records from 3,000 patients across multiple hospitals in China to find key risk factors and build a quality control system. The goal is to im…

This study looks at how well two different heart stents heal one month after being placed in people with acute coronary syndrome who also have a high risk of bleeding. Researchers will use a special imaging technique called OCT to see how the artery lining grows over the stent. T…

This study tests whether artificial intelligence can accurately evaluate how well surgeons perform a key step in heart bypass surgery. About 284 patients having their first bypass will have their surgeon's technique analyzed by AI and compared to expert human ratings. The goal is…

This study looks at whether a special ultrasound measurement of blood flow in three heart arteries can help predict serious heart problems like heart attack or need for another procedure within a year. About 494 adults with coronary artery disease will get an ultrasound during a …

This study will enroll at least 700 people with pulmonary hypertension to monitor the safety of targeted drugs. Participants will be followed every 6 months using a computerized system. The main goals are to track side effects and deaths. The study does not test a new treatment b…