China National Center For Cardiovascular Diseases

This study is testing a smartphone mini-program that gives personalized exercise plans to people with high blood pressure, blood sugar, cholesterol, and uric acid (the 'Four Highs'). Over six months, 100 participants will use the app to see if it helps them walk more and improve …

This study tests whether an AI-powered smartphone app can help adults aged 18-45 with early heart disease better manage their condition after leaving the hospital. Participants use the app to track lifestyle habits, receive reminders, and get personalized advice. The goal is to s…

This study looks at people who had heart bypass surgery combined with a procedure to clean out a blocked coronary artery. It compares two blood thinner plans: standard dual antiplatelet therapy versus adding warfarin. The goal is to see which approach better keeps the bypass graf…

This study compares a new procedure called pulsed field ablation (PFA) to standard treatment for atrial fibrillation, a common heart rhythm problem that raises stroke risk. About 1,574 adults who need catheter ablation will be randomly assigned to receive PFA or standard care. Th…

This study tests whether a computer program that uses machine learning can help doctors choose the best blood pressure medications for each patient. About 2,160 adults with high blood pressure will be enrolled across 51 clinics in China. Some clinics will use the computer program…

This study tests whether a daily pill called engagliflozin (a type of SGLT2 inhibitor) can improve heart function in people who have high blood pressure and early signs of heart failure but do not have diabetes. About 120 adults will receive either the drug or a placebo for 6 mon…

This study tests whether Xuesaitong soft capsules can reduce inflammation (measured by hsCRP levels) in 240 adults with stable coronary heart disease. Participants take the capsule or a placebo for 12 weeks. The goal is to see if this treatment helps control key risk factors for …

This study tests whether an AI-powered "Smart family doctor" app can help people who have had heart bypass surgery or a stent better control their blood pressure, diabetes, and cholesterol. About 536 adults who already have these conditions will use the app to track their health …

This study tests whether an artificial intelligence (AI) smartphone app and wearable wristband can help adults with coronary heart disease exercise safely at home after hospital discharge. About 200 low-risk patients will either use the AI platform or receive standard care. The g…

This study tests whether ademetionine, a natural substance, can improve exercise ability and heart function in people with obstructive hypertrophic cardiomyopathy (oHCM), a condition where the heart muscle thickens and blocks blood flow. About 44 adults with oHCM will be randomly…

This study tests a new way to map the heart's electrical signals during ablation for atrial fibrillation (AFib). The technique, called unipolar voltage mapping, may better identify the spots that keep AFib going. Researchers will enroll 200 adults with AFib to see if this persona…

This study tests if empagliflozin, a diabetes medicine, can help people with pulmonary arterial hypertension (PAH), a condition where high blood pressure in the lungs makes the heart work harder. About 72 adults will take either empagliflozin or a placebo daily for 12 weeks. Rese…

This study tests a new surgical method to reduce brain complications, like silent strokes, in people having heart bypass surgery. Researchers will compare the new 'no-touch' technique to standard surgery in 380 adults with blocked heart arteries. The goal is to find a safer way t…

This study tests a new technology called IVUS-FFR that uses ultrasound images from inside heart arteries to quickly check if a blockage is serious enough for a stent. Unlike the current test, it doesn't need extra wires or medication that can cause discomfort. About 292 adults wi…

This study tests whether an AI algorithm that analyzes facial images can effectively screen for coronary artery disease (CAD) in high-risk community adults (those with diabetes, high blood pressure, or over 65). About 1,392 participants will have their photo taken and then underg…

This study tests two traditional Chinese medicines (Danshen Dripping Pill and Qishen Yiqi Dripping Pill) in elderly patients aged 75-89 with coronary heart disease who still have chest pain or discomfort despite standard treatments. The goal is to see if these herbal remedies can…

This study looks at how people with complex congenital heart disease recover after heart surgery. Researchers will collect medical records from 3,000 patients across multiple hospitals in China. The goal is to find key risk factors for recovery and build a quality control system …

This study tests whether artificial intelligence can accurately evaluate how well surgeons perform a key step in heart bypass surgery. About 284 patients having their first bypass will have their surgeon's technique analyzed by AI and compared to expert human ratings. The goal is…

This study looks at whether a special ultrasound measurement of blood flow in three heart arteries can help predict serious heart problems like heart attack or need for another procedure within a year. About 494 adults with coronary artery disease will get an ultrasound during a …

This study will enroll at least 700 people with pulmonary hypertension to monitor the safety of targeted drugs. Participants will be followed every 6 months using a computerized system. The main goals are to track side effects and deaths. The study does not test a new treatment b…

This study looks at how well two different heart stents heal one month after being placed in people with acute coronary syndrome who also have a high risk of bleeding. Researchers will use a special camera (OCT) to see how the artery lining grows over the stent. The goal is to un…