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Blood pressure pills may shield brain from dementia

NCT ID NCT05125224

First seen Nov 06, 2025 · Last updated May 23, 2026 · Updated 24 times

Summary

This study looked at medical records from over 163,000 older adults with high blood pressure to see if one type of blood pressure medication (dihydropyridine calcium channel blockers) was linked to a lower risk of developing dementia compared to another (hydrochlorothiazide). Researchers analyzed existing data from 2007 to 2018. The goal was to find if a common drug could be repurposed to help prevent Alzheimer's disease and other dementias.

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Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02120, United States

Conditions

Explore the condition pages connected to this study.