Peppermint oil shows promise for lowering blood pressure in new study
NCT ID NCT05561543
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether taking peppermint oil by mouth can improve heart health in people with mild to moderate high blood pressure. 40 adults aged 18-65 with systolic blood pressure between 120-139 mmHg and not on blood pressure medication participated. Researchers measured changes in blood pressure and body fat after peppermint oil supplementation compared to a placebo.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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40 people
The number who actually took part.
- Started
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Jan 2024
- Finished
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Aug 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Aged from 18-65 years 2. Systolic blood pressure 120 to 139 mmHg 3. Not taking prescribed medicine for blood pressure management 4. have the ability to complete written questionnaires independently 5. Able to provide informed consent Exclusion Criteria: 1. diagnosed diabetes mellitus 2. known cardiovascular disease or clinically significant cardiovascular comorbidity, including coronary heart disease, symptomatic heart failure, clinically significant arrhythmia, or a history of stroke or transient ischaemic attack within the previous 6 months 3. known or suspected secondary hypertension, including renal, renovascular, or endocrine causes 4. known clinically significant renal impairment or severe hepatic disease 5. evidence or history of severe hypertension related target organ damage requiring specialist management 6. pregnant or lactating women 7. allergy to peppermint 8. habitual consumption of peppermint products 9. regular consumption of antioxidant supplements 10. body mass index larger than 40.0 kg/m² 11. current enrolment in other clinical trials or use of other external therapies likely to influence outcomes 12. condition(s) likely to compromise informed consent, protocol compliance, or outcome assessment, including severe psychiatric illness, cognitive impairment, or active substance or alcohol misuse.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of Central Lancashire
Preston, Lancashire, PR4 0PE, United Kingdom
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