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Peppermint oil shows promise for lowering blood pressure in new study

NCT ID NCT05561543

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether taking peppermint oil by mouth can improve heart health in people with mild to moderate high blood pressure. 40 adults aged 18-65 with systolic blood pressure between 120-139 mmHg and not on blood pressure medication participated. Researchers measured changes in blood pressure and body fat after peppermint oil supplementation compared to a placebo.

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Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

40 people

The number who actually took part.

Started

Jan 2024

Finished

Aug 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Aged from 18-65 years 2. Systolic blood pressure 120 to 139 mmHg 3. Not taking prescribed medicine for blood pressure management 4. have the ability to complete written questionnaires independently 5. Able to provide informed consent Exclusion Criteria: 1. diagnosed diabetes mellitus 2. known cardiovascular disease or clinically significant cardiovascular comorbidity, including coronary heart disease, symptomatic heart failure, clinically significant arrhythmia, or a history of stroke or transient ischaemic attack within the previous 6 months 3. known or suspected secondary hypertension, including renal, renovascular, or endocrine causes 4. known clinically significant renal impairment or severe hepatic disease 5. evidence or history of severe hypertension related target organ damage requiring specialist management 6. pregnant or lactating women 7. allergy to peppermint 8. habitual consumption of peppermint products 9. regular consumption of antioxidant supplements 10. body mass index larger than 40.0 kg/m² 11. current enrolment in other clinical trials or use of other external therapies likely to influence outcomes 12. condition(s) likely to compromise informed consent, protocol compliance, or outcome assessment, including severe psychiatric illness, cognitive impairment, or active substance or alcohol misuse.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Central Lancashire

    Preston, Lancashire, PR4 0PE, United Kingdom

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Other studies related to the condition(s) this trial covers.