Dermatitis

Scabies is a skin condition caused by mites that burrow into the skin and cause intense itching. This trial compares two creams used to treat it: sulfur 7% and permethrin 5%. Ninety adults with scabies were assigned to one cream or the other. Sulfur was applied each evening for t…

This study tested whether miconazole oil can cure fungal ear infections (otomycosis). 112 adults with ear fungus received either the active oil or a placebo for 14 days. Neither patients nor doctors knew who got the real treatment. After two weeks, doctors checked if the infectio…

This study tested a single oral dose of acoziborole in 208 adults with sleeping sickness, a deadly parasitic disease. Participants took three tablets once and were monitored for 18 months. The goal was to see if this simple treatment could cure both early and late stages of the d…

This trial tests whether an experimental antibody called 611, given as a shot alongside a topical corticosteroid, can improve moderate-to-severe atopic dermatitis (eczema) better than the steroid alone. Adults aged 18 to 75 with a history of inadequate response to topical treatme…

This phase 3 trial tests an oral drug called brepocitinib in 241 adults with dermatomyositis, a rare disease causing muscle weakness and skin rash. Participants receive either the drug or a placebo for 52 weeks to see if it improves symptoms. The study is active but no longer rec…

Researchers are testing whether spironolactone, a drug usually used for high blood pressure, can treat moderate acne in adult women as effectively as doxycycline, a common antibiotic. The trial enrolls women with acne who have not recently used certain treatments. Participants re…

Researchers are testing an experimental ointment called IN-A002 for mild to moderate atopic dermatitis, a common skin condition that causes itchy, inflamed skin. The trial enrolls healthy adult men and adults with atopic dermatitis to see how safe and tolerable the ointment is wh…

Researchers are testing an experimental monoclonal antibody called OpSCF in adults with moderate to severe atopic dermatitis, also known as eczema. About 50 participants receive either OpSCF or a placebo injection every two weeks for 14 weeks. The main goal is to measure how much…

Dermatophytosis, a common fungal skin infection, often becomes chronic and resists standard treatment. Researchers are comparing three oral antifungal combinations: terbinafine plus fluconazole, terbinafine plus itraconazole, and terbinafine plus voriconazole. The trial enrolls 1…

This Phase 3 trial tested netakimab, a biologic drug given as a shot, against a placebo in 202 Chinese adults with moderate-to-severe plaque psoriasis. The main goal was to see if netakimab could improve skin symptoms by at least 75% (PASI75) or achieve clear/almost clear skin (s…

This study follows people with moderate-to-severe plaque psoriasis who have already taken deucravacitinib in earlier trials. It aims to check the drug's long-term safety and how well it controls psoriasis over time. A smaller group will also test how the drug affects immune respo…

Researchers are testing an experimental drug called sonelokimab in adults with active psoriatic arthritis, a condition that causes painful, swollen joints along with skin psoriasis. The trial compares sonelokimab injections with placebo injections, and also includes a third group…

This study tests whether boric acid vaginal inserts (600 mg) taken for 7 or 14 days can safely and effectively treat yeast infections. About 400 women aged 12 and older with active symptoms will participate. The goal is to see if all signs and symptoms disappear without needing m…

Researchers are testing a drug called sonelokimab in adults with moderate to severe hidradenitis suppurativa, a chronic skin condition that causes painful lumps and abscesses. The trial compares sonelokimab, given by injection, with a placebo and with adalimumab, an existing trea…

Researchers are testing a daily application of roflumilast cream 0.3% in people with chronic plaque psoriasis to see if it is safe and effective over 24 weeks. The study includes adults and children aged 2 and older, some who have used the cream before and some who have not. Part…

This Phase 2 trial tested whether oral cimetidine (Tagamet), a common heartburn drug, can reduce light sensitivity in people with erythropoietic protoporphyria (EPP) and X-linked protoporphyria (XLP). These genetic conditions cause severe pain from sunlight exposure. The study en…

This phase 2 trial tests whether adding triamcinolone 0.1% ointment to Valchlor gel reduces contact dermatitis, a common skin reaction, in people with early-stage cutaneous T-cell lymphoma. Participants apply Valchlor nightly, with or without the steroid up to three times daily, …

This Phase 3 trial tests an experimental injection called SHR-1819 in 652 adults with moderate to severe atopic dermatitis (eczema). Half get the drug, half get a placebo. The main goal is to see if it improves skin rash and itch after 16 weeks. If it works, it may offer a new wa…

This trial tests whether a shampoo with piroctone olamine can ease seborrheic dermatitis, a common cause of dandruff, in hijab-wearing women. Researchers compare it to a standard ketoconazole shampoo to see which better improves scalp symptoms and skin health. Participants use th…

This trial tests whether injections of platelet-rich plasma from cord blood can ease vulvar lichen sclerosus, a chronic skin condition causing itching, burning, and pain. Researchers will compare CB-PRP against a placebo in 100 women, giving three treatments four weeks apart. The…

This trial tests whether adding a zinc-containing vaginal gel to the standard yeast infection pill can lower the chance of the infection returning. About 64 women with a current yeast infection will receive either the standard single dose of fluconazole alone or fluconazole follo…

This trial tests whether the probiotic Lactobacillus rhamnosus GG can ease atopic dermatitis, a chronic skin condition causing dry, itchy patches, in children aged 6 to 36 months. Half of the 100 participants receive the probiotic daily, while the other half get a placebo. Resear…

This trial tests whether combining microneedling with a chemical peel improves atrophic acne scars more than microneedling alone. Sixty adults with these scars are randomly assigned to receive microneedling followed by a 35% glycolic acid peel, microneedling followed by a 15% tri…

This study tests whether taking dexamethasone pills twice a week for 3 months can stop active vitiligo from spreading in children aged 4 to 9. Researchers will also monitor side effects, especially on growth and bone health. The goal is to control the disease, not cure it.

This phase 3 trial tests a new cream (MC2-01) containing two active ingredients for plaque psoriasis in Chinese adults. About 537 participants will use either the new cream, a standard gel, or a placebo cream for 8 weeks. The main goal is to see if the new cream clears skin bette…

This trial tests whether aloe vera gel can relieve the pain and sores of oral lichen planus as effectively as a standard corticosteroid gel. Adults aged 25 to 60 with confirmed painful oral lichen planus will apply either aloe vera or the steroid four times daily for two months. …

This study is testing the safety of the drug apremilast (Otezla) in 51 children and teens aged 6 to 17 with mild to moderate plaque psoriasis. Participants take the drug as an oral tablet, and researchers monitor for side effects, growth, and development. The goal is to see if th…

This study tested a drug called rocatinlimab in 532 teenagers with moderate-to-severe eczema that didn't improve with standard creams. The goal was to see if the drug could clear skin and reduce itching over 24 to 52 weeks. Participants received either the drug or a placebo, and …

This study tests a honey-based paste against a standard steroid ointment for treating painful mouth sores caused by oral lichen planus. Fifty-six adults with erosive or atrophic lichen planus will use the paste daily for four months. Researchers will track symptom improvement, pa…

Researchers are testing LT-002-158, an oral drug that degrades IRAK4, a protein involved in inflammation. This first-in-human trial gives the drug to healthy volunteers to check its safety, tolerability, and how the body processes it. The study also looks at how food affects drug…

This Phase 3 trial tests whether a generic version of roflumilast cream 0.3% works as well as the approved Zoryve cream for treating plaque psoriasis. About 416 people aged 12 to 75 with moderate psoriasis will apply one of the creams or a placebo daily. The main goal is to see i…

This study tested an experimental drug called daxdilimab in 12 adults with dermatomyositis or anti-synthetase myositis that wasn't well controlled by standard treatments. The goal was to see if the drug could reduce disease activity and skin symptoms, and help lower steroid use o…

This early-stage trial is testing a highly concentrated liquid antifungal, luliconazole 10% (SKX-16), applied daily to all ten toenails for 29 days in adults with moderate to severe toenail fungus. The main goals are to see how much of the drug is absorbed into the body, and whet…

This early-stage trial is testing whether an experimental drug called SHR-1819, given as a weekly injection, is safe and tolerable for adults with moderate-to-severe atopic dermatitis (a common form of eczema). The study will also look at how the drug moves through the body and w…

This trial tests whether adding a targeted ultraviolet light treatment to a common antibiotic can better reduce inflammatory acne. People aged 15 to 35 with acne on both sides of the face will take oral azithromycin, and one randomly chosen side of the face will also receive exci…

This study tests a drug called lebrikizumab against a placebo in 221 adults and teenagers with moderate-to-severe hand and foot eczema. The treatment is given as an injection under the skin over 16 weeks. The main goal is to see if the drug can clear or nearly clear the skin rash…

This trial tests whether a topical medication called pentoxifylline, typically used to improve blood flow, can help restore skin color in people with stable vitiligo. It compares this approach to another topical drug, 5-fluorouracil, and to microneedling alone, with all patients …

This phase 2 trial is investigating whether CM310, an experimental biologic given by injection, can safely and effectively control moderate-to-severe atopic dermatitis (eczema) over the long term. The study enrolls adults aged 18 to 75 with the condition and will track side effec…

This phase 2 trial is testing whether a topical gel called AT-004 can safely reduce acne lesions on the face. Adults aged 18 to 45 with mild-to-severe facial acne will apply the gel or a placebo daily for several weeks. Researchers will track changes in lesion counts and skin con…

This trial tests whether a 577-nm diode laser can safely reduce non-inflammatory acne, such as blackheads and whiteheads. Half of each participant's face receives laser treatment, while the other half serves as an untreated control. The study includes adults aged 18-40 with at le…

This study follows 200 people aged 12 and older with moderate-to-severe eczema who are starting a new prescription of abrocitinib. Researchers will track how much their skin improves over 12 months using standard eczema severity scores. The goal is to see how well the drug works …

This study will follow about 1,000 adolescents and adults in China who are prescribed upadacitinib for moderate to severe atopic dermatitis (eczema). Researchers will track how patients use the medication, any dose changes, and how well they stick to their treatment over 12 month…

This study tested a new drug called amlitelimab, given as a shot under the skin, for people aged 12 and older with moderate-to-severe atopic dermatitis (eczema) that wasn't controlled by creams. The trial included 643 participants and compared amlitelimab to a placebo, while ever…

This trial tests whether injecting a specially processed form of a patient's own fat tissue, called nanofat, can improve repigmentation in stable vitiligo when combined with standard narrowband UVB light therapy. In each of 20 adults, one vitiligo patch receives nanofat plus ligh…

This pilot study looks at whether a daily low-dose iron supplement (27 mg for three months) can improve iron status, gut health, and endurance in young female elite football players. Researchers will track diet, blood markers like hemoglobin and ferritin, gut leakage indicators, …

This trial investigates whether a topical clobetasol gel can change the levels of microRNAs in the gum fluid of people with oral lichen planus, a chronic inflammatory condition. Participants will apply either the active gel or a placebo to their lesions, and researchers will comp…

This study tested a new daily medicine called ESK-001 in 862 adults with moderate to severe plaque psoriasis. The goal was to see if it reduces psoriasis severity and is safe, comparing it to a placebo and an existing drug (apremilast). Participants took the medicine for 24 weeks…

This study tested whether a new daily pill, ESK-001, can safely reduce psoriasis severity in adults with moderate to severe plaque psoriasis. Over 900 participants took either ESK-001, a placebo (dummy pill), or an approved psoriasis drug (apremilast) for 24 weeks. Researchers me…

This trial tests whether a once-daily application of ARQ-151 cream 0.3% is safe and well-tolerated in children aged 2 to 5 with plaque psoriasis. Over four weeks, researchers measure how much of the drug enters the bloodstream and watch for any side effects or skin reactions. The…

This trial tests three ways to treat acanthosis nigricans, a skin condition causing dark, thick patches often linked to insulin resistance and obesity. About 54 people with the condition will receive either oral metformin, a topical metformin cream, or a glycolic acid chemical pe…

This trial tests a drug called briquilimab for adults with chronic spontaneous urticaria (CSU) — long-lasting hives and itching that don't get better with standard antihistamines or omalizumab. The study has three parts, with some participants getting the drug and others a placeb…

This study tested a new medicine called rocatinlimab, given as an injection, for adults with moderate-to-severe eczema that wasn't well controlled with standard creams. About 746 participants received either the study drug or a placebo, along with topical treatments. The goal was…

This trial is testing whether an experimental oral drug called rilzabrutinib can reduce the itching and hives in adults with chronic spontaneous urticaria (CSU) — a condition where hives appear without a clear trigger — even when standard antihistamines haven't helped. Participan…

This study tested a drug called tralokinumab for people with moderate-to-severe atopic hand eczema that hasn't improved with standard treatments. 235 adults received either the drug or a placebo every two weeks for 16 weeks, then everyone got the drug for another 16 weeks. The go…

This study tests whether baricitinib, an oral anti-inflammatory drug, is safe and effective for children aged 2 to 17 with moderate to severe atopic dermatitis (eczema). About 516 participants will receive either baricitinib or a placebo, along with standard topical steroids. The…

This Phase III trial is testing an investigational biologic called LZM012 in adults with moderate-to-severe plaque psoriasis. The drug targets two inflammatory proteins, IL-17A and IL-17F, to potentially reduce skin symptoms. Participants will receive LZM012 injections, and resea…

This trial tests whether a topical ozonated vegetable oil can reduce the severity of mild-to-moderate atopic dermatitis (eczema) in children aged 1 month to 6 years. Over 14 days, researchers compare the oil against a placebo, measuring changes in a standard eczema severity score…

This study tests a drug called certolizumab pegol (Cimzia) in children aged 6 to 17 with moderate to severe plaque psoriasis. The goal is to see how the drug moves through the body and whether it is safe. Some children will get the drug, others a placebo. The study is active but …

This phase II trial is testing whether an experimental drug called MG-K10 can reduce the severity of moderate-to-severe atopic dermatitis, a chronic inflammatory skin condition. About 60 adults who have not responded well to topical treatments will receive either MG-K10 or a plac…

This Phase 3 trial tests whether an experimental oral drug, HPP737, can reduce psoriasis severity in adults with moderate-to-severe plaque psoriasis. Participants take HPP737 or an active control drug daily for 16 weeks. Researchers measure skin clearance using standard scores li…

This Phase 3 trial tests whether an oral drug called HPP737 can safely improve moderate-to-severe plaque psoriasis in adults. Participants take HPP737 or a placebo daily for 16 weeks, with doctors measuring skin clearance using standard scores like PASI. The study aims to see if …

This study tested two doses of bimekizumab, a drug that targets inflammation, in 41 adolescents aged 12 to 17 with moderate to severe plaque psoriasis. The main goals were to measure how the drug behaves in the body and to check its safety. Researchers also looked at how well it …

This trial tests whether an oral drug called HPP737 can safely improve moderate-to-severe plaque psoriasis in adults. Participants take either HPP737 or a placebo daily for 85 days. Researchers measure skin improvement using standard scoring tools and track any side effects. The …

This phase 2 trial tests whether a Chinese medicine formula called Inflammatory Skin Disease Formula (ISDF) can reduce the severity of plaque psoriasis, a common inflammatory skin condition. Adults with mild to moderate psoriasis will take either ISDF granules or a placebo twice …

This pilot study tests whether a modified Chinese herbal formula, Modified Huang-Lian-Jie-Du Decoction (MHLJDD), can reduce eczema symptoms in children aged 4 to 17. Participants take either the herbal granules or a placebo twice daily for 12 weeks. The study measures changes in …

This phase 2 trial tests whether a modified version of the traditional Chinese herbal formula Xiao-Feng Powder can reduce itching and wheals in people with chronic urticaria (hives lasting more than 6 weeks). About 58 adults will receive either the herbal granules or a placebo tw…

This trial tests whether taking a specific probiotic supplement (Lactobacillus crispatus Lc-G22) alongside standard antifungal treatment can help prevent repeat vaginal yeast infections. One hundred women with a history of frequent yeast infections will receive either the probiot…

This study tested a drug called rocatinlimab in 187 teenagers aged 12 to 17 with moderate-to-severe eczema that didn't respond well to standard creams. The goal was to see if the drug is safe and tolerable over 52 weeks. Participants received regular injections, and researchers t…

This trial tests whether efgartigimod, an injected drug that blocks certain immune antibodies, can improve muscle strength and function in adults with active idiopathic inflammatory myopathy — a group of rare autoimmune diseases that cause muscle inflammation and weakness. About …

This study tested a new medication called rocatinlimab for adults with moderate-to-severe eczema (atopic dermatitis). About 769 people took part to see if the drug can clear skin and reduce itching better than a placebo. The goal is to provide a new treatment option for those who…

This study looks at whether it is safe for people aged 12 and older with hereditary angioedema (HAE) to switch from their current preventive medicine to a new monthly injection called garadacimab. Researchers will monitor for side effects over about 3 months. The goal is to see i…

This study tested a new medicine called amlitelimab, given as a shot under the skin, for people aged 12 and older with moderate-to-severe eczema that didn't get better with creams or other treatments. The goal was to see if it can clear or nearly clear the skin and reduce itching…

This trial compares two common antifungal creams — oxiconazole 1% and clotrimazole 1% — to see which works better for treating dermatophytosis, a fungal skin infection often called ringworm. About 164 adults with mild to moderate infections will apply one of the creams daily. The…

This phase 2 trial tests whether an experimental oral drug called TLL018 can improve skin clearance in adults with moderate-to-severe plaque psoriasis. Participants receive one of two doses of TLL018 or a placebo for 12 weeks. The main goal is to see if at least 75% of skin plaqu…

This study tests whether lebrikizumab, an injectable biologic, can improve skin symptoms in adults and adolescents (aged 12 and older) with moderate-to-severe atopic dermatitis, also known as eczema. Participants receive lebrikizumab for 24 weeks, and doctors measure changes in e…

This study tests an experimental oral medication called QY201 in adolescents aged 12 to 17 with moderate to severe atopic dermatitis (eczema). Participants take either 10 mg or 20 mg of QY201 twice daily for 28 days. The main goal is to understand how the drug moves through the b…

This pilot study tests an experimental drug called ritlecitinib in people with cicatricial alopecia, a type of hair loss where hair follicles are permanently destroyed and replaced by scar tissue. The drug works by blocking certain enzymes involved in inflammation. Researchers wi…

This phase 2 study tests whether rilzabrutinib, an oral medication, can reduce eczema severity in adults with moderate-to-severe atopic dermatitis who do not respond well to or cannot tolerate topical corticosteroids. Participants receive either rilzabrutinib or a placebo for 16 …

This study tests two types of light therapy—low-level light and intense pulse light—to kill Demodex mites that cause eyelid inflammation (blepharitis). 88 adults with confirmed mite infections will receive one of four treatments: sham, blue light alone, IPL alone, or both. All wi…

This trial compares unstable resistance training (exercises on unstable surfaces like balance pads) with traditional resistance training in male college basketball players. The goal is to see if the unstable version improves dynamic balance and the ability to quickly change direc…

This study tests whether injecting a person's own fat-derived stem cells into stable vitiligo patches, alone or combined with excimer light therapy, can safely bring back skin color. Fifteen adults with stable vitiligo patches will receive the treatment. The goal is to see if the…

This study tested whether cleaning the eyelids with wipes containing chlorhexidine can treat blepharitis caused by Demodex mites. 106 adults with the condition used the wipes twice daily for four weeks. Researchers measured mite counts and eyelash debris before and after treatmen…

This trial investigates whether taking a postbiotic supplement daily for four weeks can help ease symptoms of vaginal yeast infections in women. Participants are sexually active women with a confirmed yeast infection. The study compares the postbiotic to a placebo to see if it im…

This Phase 3 study tests a cream called roflumilast (Zoryve) for treating plaque psoriasis in Chinese patients aged 6 years and older. The cream is applied once daily to reduce skin plaques. Researchers will measure how many patients achieve clear or almost clear skin after 8 wee…

This study tests whether structured physical games can improve memory, attention, gross motor skills, and social adaptability in children aged 4 to 6. Over 8 weeks, preschoolers play specially designed games like 'Eagle Catching Chicks' and 'Puppy Seeking Bones' during class. Res…

This study tests an experimental drug called SHR-1819 in children and adolescents aged 6 to 17 with moderate-to-severe atopic dermatitis (a type of eczema). The main goal is to check the drug's safety and how the body processes it. Researchers will also look at changes in skin-re…

This phase 3 study tested the drug bimekizumab in 133 Chinese adults with moderate to severe plaque psoriasis. Participants received either bimekizumab or a placebo for 16 weeks. The main goals were to see if bimekizumab could clear at least 90% of psoriasis (PASI90) and achieve …

This phase 3 study tested a drug called rocatinlimab in 726 adults with moderate-to-severe atopic dermatitis (eczema) that wasn't well controlled by creams. Participants received either the drug or a placebo as a shot under the skin for 24 weeks. The main goals were to see if the…

This study tested a drug called nemolizumab in 109 children aged 2 to 11 with moderate-to-severe eczema. The drug is given as a shot under the skin every 4 weeks for a year. Researchers measured how the drug moves through the body, its safety, and whether it improves eczema sympt…

This completed Phase 3 trial tested the drug guselkumab (Tremfya) in 211 people with skin of color who have moderate-to-severe plaque psoriasis or scalp psoriasis. Participants received either guselkumab or a placebo injection. The study measured how well the drug cleared skin le…

This completed study tested two topical serums for treating toenail fungus (onychomycosis). 44 adults with mild to moderate infection applied one or both serums daily for 112 days. Researchers measured the change in healthy nail area using photos. The goal was to see if using bot…

This study is testing how the drug guselkumab affects the immune system in people with two types of psoriasis: plaque and guttate. Twenty-five adults will receive guselkumab injections over 44 weeks. Researchers will measure changes in immune cells in the skin to understand how t…

This study tests whether adding a weight-loss drug (tirzepatide) to a standard psoriasis treatment (ixekizumab) helps people with moderate-to-severe plaque psoriasis who are also overweight or obese. About 250 adults will receive either ixekizumab alone or both drugs together for…

This study tested a daily pill called upadacitinib in 912 teens and adults with moderate to severe eczema (atopic dermatitis) that was not well controlled with creams. Participants received either the study drug or a placebo for 16 weeks. The main goals were to see if the drug co…

This study tested whether dupilumab, a drug already used for asthma and eczema, can help people with bullous pemphigoid, a painful blistering skin condition. 106 adults received either dupilumab or a placebo, plus standard steroid treatment. The main goal was to see if more peopl…

This completed trial tested a herbal ointment made from Syzygium formosum leaves in 90 people with mild to moderate atopic dermatitis (eczema). The ointment was compared to standard moisturizers to see if it was safe and effective. The study measured skin severity, water loss, an…

This study tested whether a single dose of an oral drug called moxidectin can cure scabies, a skin condition caused by tiny mites. 200 adults with confirmed scabies received either 8 mg, 16 mg, or 32 mg of moxidectin or a placebo. The main goal was to see if the drug could comple…

This study compared two types of ultraviolet light treatments—an excimer lamp and an excimer laser—for repigmenting white patches caused by vitiligo. Adults with at least two matching patches of vitiligo received both treatments on different patches twice a week for 12 weeks. The…

This study investigates whether clascoterone cream 1%, an FDA-approved acne medication, works by reducing sebum (skin oil) production. Researchers will measure forehead oil levels and changes in skin bacteria in 40 participants aged 12 and older with mild to moderate acne. The go…

This phase 2 trial tested whether adding the oral drug baricitinib to phototherapy (light treatment) helps restore skin color in adults with progressive vitiligo. 49 participants received either baricitinib plus phototherapy or a placebo plus phototherapy for 36 weeks. The main g…

This study looked at how a new oral medication (sebetralstat) works in the bodies of 11 teenagers aged 12 to 17 with hereditary angioedema (HAE) types I or II. The goal was to measure drug levels and timing in the blood. All participants were already in a larger HAE trial. The st…

This study looks at how safe and effective upadacitinib is for Chinese adolescents and adults with moderate to severe atopic dermatitis (eczema). About 200 participants will take the drug as prescribed by their doctor and be followed for up to 24 months. The goal is to track seri…

This study looked at the long-term safety of an oral medication called KVD900 for treating swelling attacks in people with hereditary angioedema (HAE) types I or II. The trial enrolled 145 adolescents and adults who had already completed a previous study. Participants took KVD900…

This study looked at whether nemolizumab, a drug for moderate-to-severe eczema, interferes with the body's ability to respond to tetanus and meningococcal vaccines. 242 adults and teens with eczema received either nemolizumab or a placebo, plus the vaccines. The goal was to see i…

This study looked at how the drug abrocitinib affects the skin barrier in 20 adults with moderate to severe atopic dermatitis (eczema). Researchers measured water loss from the skin and changes in skin-related genes at 2 and 12 weeks. The goal was to see if the treatment helps re…

This study tested a new oral medication, JNJ-77242113, for long-term control of moderate-to-severe plaque psoriasis. 227 adults who completed a previous 16-week study continued treatment for up to 36 more weeks. The goal was to see how well the drug kept skin clear over time.

This study tested the drug dupilumab (Dupixent) in 124 adolescents and adults with darker skin tones who have moderate-to-severe eczema. Participants received injections every two weeks for 24 weeks. The goal was to see if the drug safely improves skin symptoms and quality of lif…

This phase 2 trial tested whether adding methotrexate (a drug used for arthritis) to standard UVB light therapy works better than light therapy alone for adults with active, spreading vitiligo. Thirty-two participants were randomly assigned to receive either methotrexate pills pl…

This phase 2a trial tested an oral drug called EVO756 in 30 adults with chronic inducible urticaria, a condition where physical triggers like scratching or cold cause hives. The study aimed to see if the drug is safe and can reduce wheals. Results are not yet available.

This completed trial tested whether adding vitamin D supplements to standard acne treatment (azithromycin and a topical retinoid) improves acne more than standard treatment alone. Fifty-eight people aged 13 to 40 with acne vulgaris took part. The main goal was to see if the combi…

This study followed 80 patients with pemphigus, a rare autoimmune disease that causes painful blisters on skin and mucous membranes. Researchers wanted to see how safe and effective rituximab (a drug that targets certain immune cells) is over the long term, compared to standard h…

This study looked at the long-term safety and effectiveness of lebrikizumab for adults and teens with moderate-to-severe atopic dermatitis (eczema). Participants who completed a previous year-long study could join this 2-year extension. The main goal was to see how many people st…

This study tested two treatments for toenail fungus in 27 Asian adults: a light-activated dye (methylene blue photodynamic therapy) and a medicated nail polish (amorolfine). The goal was to see which worked better and was safer. Participants received either the light treatment or…

This study followed 305 Canadian adults and children (ages 6+) with moderate-to-severe eczema who were prescribed Dupixent as part of their routine care. Researchers measured how many patients achieved at least a 75% reduction in eczema severity after 6, 12, and 18 months. The go…

This study tested an oral drug called GLPG3667 (Cadefrecitinib) in 40 adults with dermatomyositis, a rare disease causing muscle weakness and skin rash. Participants took the drug or a placebo daily for 24 weeks to see if it improves symptoms. The trial is complete, and results w…

This study tested a drug called tralokinumab in 28 children aged 6 to 12 with moderate-to-severe eczema. The goal was to see how the drug moves through the body and if it is safe. Children received injections over several weeks and used moisturizers daily. The trial is complete, …

This completed study tested two older, low-cost drugs—methotrexate and azathioprine—against chronic actinic dermatitis, a painful skin reaction to sunlight. Fifty adults were randomly assigned to one drug for 24 weeks. Researchers tracked eczema severity and safety. The goal was …

This phase 2 trial tested a drug called orticumab in 77 adults with moderate-to-severe psoriasis who also had cardiometabolic risks (like obesity and high cholesterol). The goal was to see if orticumab could safely reduce skin plaques and inflammation linked to heart disease. Par…

This early trial tested a new drug called navenibart in 29 people with hereditary angioedema (HAE), a condition that causes sudden, painful swelling attacks. Participants received one or two doses of the drug to check its safety and how well it might reduce attacks. The study is …

This study tested the long-term safety and effectiveness of donidalorsen, an injectable drug, in 20 people with hereditary angioedema (HAE), a condition that causes sudden, painful swelling attacks. Participants received different doses over 64 weeks. The main goal was to check f…

This early-phase trial tested the drug rituximab in 3 people with ocular cicatricial pemphigoid, a rare autoimmune disease that causes scarring in the eye and can lead to blindness. The goal was to see if the drug could stop further scarring when standard treatments had failed. T…

This study tested a light therapy device called ToeFX for mild to moderate toenail fungus. 126 people with fungal infection in one big toenail used the device. Researchers measured new clear nail growth after 12 months to see if the treatment worked and was safe.

This study tested an oral tablet called JNJ-77242113 in 90 adults with moderate-to-severe plaque psoriasis. Participants were randomly assigned to receive the drug or a placebo for 16 weeks. The main goal was to see if the drug could improve psoriasis symptoms by at least 75% com…

This completed phase 3 trial tested the drug guselkumab against a placebo in 338 adults with moderate plaque psoriasis covering only 2-15% of their body but including special sites like the scalp, face, or genitals. The goal was to see if guselkumab could clear or nearly clear ps…

This study tested a new drug called SHR-1819 in 158 adults with moderate to severe atopic dermatitis (a type of eczema). Participants received one of three doses of the drug or a placebo. The main goal was to see if the drug could reduce eczema severity by at least 75% after 16 w…

This study tracked over 2,300 adults in Korea who were prescribed Skyrizi (risankizumab) for moderate to severe plaque psoriasis or psoriatic arthritis. Researchers monitored side effects and symptom changes for 52 weeks during routine doctor visits. The goal was to confirm the d…

This study tested two ways to treat bullous pemphigoid, a severe blistering skin condition. One group used strong steroid creams for 9 months, while the other used steroids plus methotrexate for 4 weeks, then methotrexate alone for 8 months. The goal was to see if the combination…

This study tested whether a higher dose of the drug brodalumab works better than the standard dose for people with moderate-to-severe plaque psoriasis who weigh at least 120 kg. The trial involved 385 adults and lasted 52 weeks. The main goal was to see if more patients on the hi…

This study looked at 781 adults with moderate-to-severe plaque psoriasis and metabolic syndrome (a cluster of conditions like high blood pressure and obesity). Researchers wanted to see if adding a lifestyle intervention (diet and exercise) to the drug Secukinumab (Cosentyx) impr…

This phase 2a trial tested an experimental drug called AMG 714 in 60 adults with vitiligo, a condition that causes white patches on the skin. The drug works by blocking a protein called IL-15, which may play a role in the disease. Participants received either AMG 714 or a placebo…

This study tested the drug baricitinib, given with steroids, in 16 children aged 3-18 with newly diagnosed juvenile dermatomyositis, a rare disease causing muscle weakness and skin rashes. The goal was to see if baricitinib works better than the standard treatment (methotrexate p…

This study tested two creams for mild to moderate eczema in 40 children aged 1-12. One cream was a steroid (fluticasone), the other a non-steroid (crisaborole). Both were applied twice daily for 6 weeks, then twice weekly for 12 weeks if the skin improved a lot. Both treatments w…

This study compared two ear drop treatments for otomycosis, a fungal infection of the outer ear that causes itching, discharge, and blockage. Sixty patients were randomly assigned to receive either clotrimazole or 2% salicylic acid drops three times daily for two weeks. The main …

This study tested a new drug called bimekizumab in 567 adults with moderate to severe plaque psoriasis. Participants received either bimekizumab, a placebo, or another active drug. The main goal was to see how well bimekizumab cleared skin lesions after 16 weeks. Results showed s…

This phase 3 study tested bimekizumab, a drug given by injection, against a placebo in 435 adults with moderate to severe plaque psoriasis. The main goal was to see how many people achieved at least 90% skin clearing after 16 weeks. The trial also looked at complete clearing and …

This study compares two already-approved drugs, risankizumab (injection) and deucravacitinib (pill), for adults with moderate plaque psoriasis. About 393 participants who haven't used biologics before will receive one of the treatments for up to 44 weeks. The goal is to see which…

This study tested whether a single cycle of rituximab can control bullous pemphigoid, a severe blistering skin condition. Eighteen adults with steroid-dependent or relapsing disease were enrolled. Researchers checked disease control weekly for a month and then monthly for two yea…

This Phase 3 trial tested bimekizumab against secukinumab and placebo in 743 adults with moderate to severe plaque psoriasis. The main goal was to see how many patients achieved complete skin clearance (PASI100) at 16 weeks. Bimekizumab showed superior results compared to secukin…

This study tested a new medicine called bimekizumab against an existing drug (adalimumab) in 478 adults with moderate to severe plaque psoriasis. The goal was to see if bimekizumab could clear more skin at 16 weeks. Participants received either bimekizumab or adalimumab, and then…

This study looked at the long-term safety and tolerability of bimekizumab in over 1,300 adults with moderate to severe plaque psoriasis. Participants who completed earlier studies received bimekizumab injections over several years. The main goal was to track side effects and see …

This study tested a single dose of the oral drug acoziborole in 35 children aged 1 to 14 with sleeping sickness (g-HAT). The goal was to see how the drug works in the body and if it is safe and effective. This simpler treatment could help control the disease in remote areas where…

This study tested a new ointment (LEO 90100) against a standard one (Daivobet) for stable plaque psoriasis in 604 Chinese adults. Participants applied the treatment for 4 weeks. The goal was to see if the new ointment could clear or nearly clear psoriasis patches better than the …

This study tested a special gel, CGB-400, on 15 adults with toenail fungus. The goal was to see if the gel could clear the fungus and make the nails look better. Participants applied the gel for 12 weeks, with follow-up visits to check progress.

This study followed 48 people with hereditary angioedema (HAE) in Poland who were taking lanadelumab as part of a national drug program. Researchers tracked how many participants remained attack-free over 24 months, how many attacks still needed rescue treatment, and the severity…

This study tested a biologic drug called SIM0718 in 259 adults and teens with moderate to severe atopic dermatitis (eczema) that did not respond well to creams. Participants received either the drug or a placebo every two weeks for 16 weeks. The goal was to see if the drug could …

This completed Phase 2 trial tested a new ointment called CGB-500 (containing tofacitinib) against an approved cream (ruxolitinib) for atopic dermatitis, a type of eczema. Only 3 people aged 12 and older took part, applying both treatments to different skin areas twice daily for …

This study tested whether the drug apremilast, taken as a pill twice daily, combined with narrowband UVB light therapy can help restore skin color in people with widespread vitiligo. 80 adults with stable or slowly progressing vitiligo covering at least 10% of their body took par…

This Phase 2 trial tested the drug bimekizumab in 49 adults with moderate to severe plaque psoriasis. Participants received either bimekizumab or a placebo, and researchers measured how well the drug cleared skin and how long it stayed in the body. The goal was to see if bimekizu…

This phase 2 trial tested avdoralimab, an antibody that blocks a specific immune signal, added to standard steroid cream for bullous pemphigoid—a severe blistering skin condition mostly affecting older adults. Fifteen participants received the combination to see if it leads to co…

This study tested whether teenagers and adults with moderate-to-severe eczema (atopic dermatitis) could successfully give themselves injections of the drug rocatinlimab at home using special devices. The main goal was to see how many full doses were self-administered correctly up…

This study tested whether adding the cholesterol drug atorvastatin to standard UVB light therapy works better than UVB alone for active vitiligo. 28 adults with active, non-segmental vitiligo took part. The main goal was to see if the combination reduced the amount of skin color …

This study tested a new dual laser treatment for vulvar lichen sclerosus, a chronic skin condition causing discomfort. 66 participants were randomly assigned to receive either laser therapy or standard steroid cream. The goal was to see if the laser works as well as the cream, po…

This phase 2 trial tested a cream called ruxolitinib (Opzelura) on 49 people with nonsegmental vitiligo affecting the genitals. Participants applied the cream twice daily for up to 48 weeks to see if it made the white patches less noticeable. The study measured success based on p…

This study tested a new ankle training machine in 14 athletes with chronic ankle instability. The machine allows for multi-directional strengthening while sitting. Researchers compared it to standard resistance band training over six weeks, measuring muscle strength, balance, and…

This study tested whether psoriasis patients who are stable on biologic drugs (IL17 or IL23 inhibitors) can safely reduce their dose without their skin condition getting worse. Researchers enrolled 244 adults with plaque psoriasis who had been on a normal dose for at least 6 mont…

This Phase 3 trial tested a drug called imsidolimab in 45 adults with generalized pustular psoriasis (GPP), a rare and severe skin condition that causes painful pustules. Participants received either a single intravenous dose of imsidolimab (750 mg or 300 mg) or a placebo. The ma…

This study tested a new drug, AK120, in 450 adults with moderate to severe atopic dermatitis (eczema). The main goal was to check for side effects and see how well the drug works. Researchers measured changes in eczema severity using standard skin scores.

This study tested an experimental oral drug called ATI-2138 in 14 adults with moderate to severe atopic dermatitis (eczema). Participants took the pill twice daily for 12 weeks. Researchers tracked safety, side effects, and skin improvement using standard eczema scores. The goal …

This completed Phase 1 trial compared a generic tretinoin gel (0.04%) to the brand-name RETIN-A MICRO for treating acne vulgaris. Over 1,000 participants aged 12 to 40 with mild to moderate acne applied the gel daily for 12 weeks. The goal was to see if the generic version works …

This study looked at whether QLETLI, a biosimilar of adalimumab, is safe and effective for children and teens aged 4 to 17 with severe plaque psoriasis. A total of 80 participants were followed for 24 weeks. The main goal was to see how much their psoriasis symptoms improved, mea…

This study tested the drug lebrikizumab in 90 adults and teens with moderate-to-severe eczema who have skin of color. The goal was to see if the drug is safe and helps clear skin. Participants received injections over 24 weeks, and doctors measured improvement using a standard ec…

This study looked back at 275 pemphigus patients to see how different doses of rituximab affected disease control and relapse. Pemphigus is a rare autoimmune disease that causes painful blisters on skin and mucous membranes. Researchers tracked outcomes like flare-ups, side effec…

This study looked at the long-term safety of the drug SHR-1819 in 79 adults with moderate to severe eczema who had already taken part in earlier studies of the same drug. Researchers tracked side effects and how well the drug controlled the disease over time. The goal was to see …

This observational study followed 331 adults with moderate-to-severe plaque psoriasis who were treated with tildrakizumab (Ilumetri) as part of their routine care. Researchers tracked how much the skin cleared and how quality of life improved over up to two years. The goal was to…

This study tested the drug upadacitinib in people with moderate to severe atopic dermatitis (eczema) who also have prurigo nodularis, a condition causing intense itching and hard bumps. The goal was to see if the drug reduces itching and improves skin. The study was observational…

This study tested two antifungal creams—oxiconazole and clotrimazole—against each other in 386 adults with jock itch (tinea cruris). The goal was to see which one better relieved itching and redness. Both creams are already used for fungal skin infections, so this trial aimed to …

This Phase 3 study tested ritlecitinib, an oral drug, in 607 adults and adolescents with nonsegmental vitiligo (a type of white patches on the skin). Participants took either the drug or a placebo daily for 52 weeks. The main goals were to see if the drug could improve skin color…

This study tested the drug risankizumab (Skyrizi) in 214 adults with moderate to severe genital or scalp psoriasis. Participants received either the drug or a placebo for 16 weeks, then all received the drug. The goal was to see if it could clear or nearly clear the skin in these…

This study tested a drug called lebrikizumab in 86 adults and teens with moderate-to-severe eczema who had already tried dupilumab. The goal was to see if lebrikizumab could safely improve their skin condition. Researchers measured how many participants achieved at least a 75% im…

This study tested whether adding isotretinoin (a retinoid that changes skin oil and growth) to the standard antifungal itraconazole works better than itraconazole alone for adults with resistant Trichophyton fungal skin infections. 148 adults aged 18-65 with confirmed infection w…

This study tested a new oral medication, oteseconazole, to see if it can prevent recurrent yeast infections in women who have had at least three infections in the past year. Over 400 participants took either the study drug or a placebo for 12 weeks after an initial treatment, and…

This study tested a new oral medication, oteseconazole, to see if it can prevent recurrent yeast infections in women who have had at least three infections in the past year. Participants first received standard treatment for their current infection, then took either oteseconazole…

This study tested an experimental drug called JNJ-77242113 in 255 adults with moderate-to-severe plaque psoriasis. The goal was to see if different doses could clear at least 75% of skin symptoms after 16 weeks compared to a placebo. Participants had psoriasis for at least 6 mont…

This study tested whether adding metformin, a common diabetes drug, to cyclosporine works better for psoriasis than cyclosporine alone. Thirty-two adults with moderate to severe psoriasis took part. Researchers measured skin improvement, body surface area affected, and quality of…

This study tested whether people with moderate-to-severe plaque psoriasis who achieve complete skin clearance after 20 weeks of guselkumab (Tremfya) can maintain that control with injections every 16 weeks instead of every 8 weeks. About 880 participants were enrolled, and the ma…

This study tested the safety and effectiveness of abrocitinib, a daily pill, for people aged 12 and older with moderate to severe eczema. Participants took either 100 mg or 200 mg of abrocitinib for up to 92 weeks, with some continuing until the drug became commercially available…

This study tested the drug apremilast (Otezla) in 203 Chinese adults with moderate to severe plaque psoriasis. Participants took either apremilast or a placebo pill twice daily for 16 weeks. The main goal was to see if more people on apremilast achieved at least a 75% improvement…

This Phase 2 trial tested an experimental oral drug called SCD-044 in 250 adults with moderate to severe atopic dermatitis (eczema). Participants received one of three doses of SCD-044 or a placebo for 16 weeks. The main goal was to see if the drug could reduce eczema severity by…

This study looked at the long-term safety and effects of the drug apremilast in 160 children aged 6 to 17 with moderate to severe plaque psoriasis. Participants who had already completed one year of treatment could continue taking the drug for up to 208 weeks (about 4 years). The…

This study looked at the long-term safety of a cream called roflumilast for people with mild to moderate eczema (atopic dermatitis). Over 1,200 participants, ages 2 and up, applied the cream once daily for up to 52 weeks. The main goal was to track any side effects, with secondar…

This study tested the safety and effectiveness of oral ivermectin for treating scabies in children weighing 5 to less than 15 kilograms. 240 children participated, receiving either ivermectin, a standard permethrin cream, or a placebo. The goal is to see if ivermectin can be a sa…

This completed Phase 2 trial tested oral ivermectin minitablets in 13 children aged 3 months and older weighing 5 to less than 15 kilograms who had scabies. The study aimed to check the safety, how the drug works in the body, and how well it treats the infection. Results will hel…

This small study tested whether a short course of HIV drugs (emtricitabine and tenofovir) could reduce inflammation in people with plaque psoriasis. Only 8 people took part, and the main goal was to see changes in certain markers in skin biopsies. The study is complete, but resul…

This large study looked at whether taking daily vitamin D or fish oil supplements could lower the risk of developing autoimmune diseases (like rheumatoid arthritis), reduce signs of inflammation in the blood, and ease chronic knee pain. Over 25,000 adults without prior cancer or …

This study compared two common antibiotics, doxycycline and TMP-SMX, for treating uncomplicated skin infections like boils and cellulitis. 269 people aged 9 to 85 took one of the drugs for 7 days. Researchers checked if the infection cleared up early, at the end of treatment, and…

This study tested the long-term safety of a daily pill called ASC40 (Denifanstat) in 240 people with moderate to severe acne who had already completed a previous phase 3 trial. Participants took the drug once daily for up to 40 weeks, with regular blood tests and checkups to moni…

This study looked at whether tildrakizumab, a drug already approved for psoriasis, can improve blood flow to the heart in people with moderate-to-severe psoriasis. 36 adults took the drug for 6 months, and researchers measured heart function using special scans. The goal was to s…

This study tested an oral medication called deucrictibant for quickly treating attacks of hereditary angioedema (HAE), a condition causing sudden, painful swelling. The trial involved 134 adolescents and adults with HAE types 1, 2, or 3. Participants took either the drug or a pla…

This study tested three types of chemical peels—50% glycolic acid, 30% salicylic acid, and modified Jessner's—on 90 adults with mild to moderate facial acne and post-acne dark spots. Participants received one type of peel, and doctors measured improvements in acne severity and pi…

This study tested the long-term safety and effectiveness of a drug called KZR-616 in 18 adults with active polymyositis or dermatomyositis, rare diseases that cause muscle inflammation and weakness. Participants who completed an earlier study received weekly injections of KZR-616…

This study tested an oral drug called BCX4161 to prevent attacks of hereditary angioedema (HAE), a condition that causes sudden, painful swelling. Over 12 weeks, 110 adults with HAE took either a low dose, high dose, or placebo pill. Researchers tracked how many swelling attacks …

This completed study followed 2759 adults with moderate to severe plaque psoriasis to see how well risankizumab works compared to other commonly used biologic drugs. Researchers measured skin clearance and how long patients stayed on treatment. The goal was to understand real-wor…

This Phase 2 trial tested a drug called KZR-616 (zetomipzomib) in 25 adults with active polymyositis or dermatomyositis, two rare diseases that cause muscle inflammation and weakness. Participants received either the drug or a placebo for 16 weeks, then switched to the other trea…

This study tested a new oral medication, SAR441566, in 221 adults with moderate to severe plaque psoriasis. Participants received either the drug or a placebo for 12 weeks. The main goal was to see if the drug could reduce psoriasis severity by at least 75%. Results will help det…

This study tested the long-term safety and effectiveness of lebrikizumab, a drug for moderate-to-severe atopic dermatitis (eczema). Over 1,100 participants who had already taken the drug in earlier studies were followed for up to 33 months. The goal was to see how well the drug c…

This pilot study tested higher-than-standard doses of risankizumab in 20 adults with moderate-to-severe plaque psoriasis. The goal was to see if higher doses could better reduce certain skin immune cells (resident memory T cells) and improve skin clearance. The study was complete…

This study tested a drug called efgartigimod in 98 adults with moderate to severe bullous pemphigoid, a condition causing painful blisters and itching. The goal was to see if the drug could control the disease and allow patients to stop taking steroids. The trial was split into t…

This study tested a vaginal pessary (Gedea) in 26 women with yeast infections. Participants used the device daily for 6 days. Researchers checked if symptoms like itching and burning went away by day 7 to 14. The goal was to see if the device could safely treat the infection with…

This study compared an online, team-based care model to standard in-person care for managing atopic dermatitis (eczema). 300 patients were randomly assigned to either online or in-person care for 12 months. The goal was to see if the online approach could match in-person care in …

This study tested an eyedrop called TP-03 in 39 people with meibomian gland dysfunction (a common cause of dry eye) linked to Demodex mites. The goal was to compare two dosing schedules (twice vs. three times daily) for safety and effectiveness. The results could lead to a new tr…

This study tested whether methotrexate, an older drug used for arthritis, works as well as cyclosporine for people with moderate to severe atopic dermatitis (eczema). One hundred adults received either drug for 24 weeks. The main goal was to see if eczema severity dropped by half…

This study tested an oral drug called upadacitinib (RINVOQ) against a placebo and an injected drug (adalimumab/Humira) in 1705 people with active psoriatic arthritis who had not responded well to standard non-biologic treatments. The goal was to see if upadacitinib reduces joint …

This study tested whether dupilumab, an injected drug for eczema, improves skin barrier function in 52 people with moderate to severe atopic dermatitis. Researchers measured water loss from the skin after tape stripping to assess barrier repair over 16 weeks. The goal was to see …

This study tested a drug called imsidolimab in 8 adults with generalized pustular psoriasis (GPP), a rare and severe skin condition. The drug is an antibody that targets inflammation. Researchers measured how well it worked using skin scores and other health markers. The goal was…

This study looked at how dupilumab, an injectable biologic drug, affects the skin barrier in 41 children aged 6 to 12 with moderate to severe atopic dermatitis (eczema). Researchers measured water loss through the skin after removing thin layers with tape to assess barrier functi…

This phase 2 trial tested a monthly injection called imsidolimab (ANB019) in 59 adults with palmoplantar pustulosis, a chronic skin condition causing painful, pus-filled blisters on the palms and soles. The study compared the drug to a placebo to see if it could reduce the severi…

This study tested the drug dupilumab (Dupixent) in 44 Chinese patients aged 12 to 65 with moderate to severe atopic dermatitis (eczema). The goal was to see if the drug improves skin barrier function by measuring water loss through the skin over 16 weeks. Participants received du…

This study compared blue light therapy to targeted narrow band UVB for treating stable non-segmental vitiligo in 30 patients. The goal was to see which treatment better restores skin color. Both are light-based therapies, but blue light may be less harsh on the skin.

This phase 3 trial tested whether Bmab 1200, a biosimilar of the drug Stelara, works as well as Stelara for people with moderate to severe plaque psoriasis. 384 adults received either Bmab 1200 or Stelara over 40 weeks. The main goal was to see how much psoriasis symptoms improve…

This phase 3 study tested upadacitinib, an oral anti-inflammatory drug, in 642 adults with active psoriatic arthritis who had not responded well to at least one biologic treatment. Participants received either 15 mg or 30 mg of upadacitinib daily or a placebo. The main goal was t…

This study followed 140 people with hereditary angioedema (HAE) who were already taking lanadelumab. Researchers compared the number of swelling attacks during treatment to the number before starting the drug. Participants reported their symptoms via a smartphone app and during c…

This study tested whether starting treatment early with UVB light therapy and low-dose steroids can stop vitiligo from spreading and improve skin color return. 51 people with different stages of vitiligo were treated for 6 months. Researchers took skin samples to see how immune c…

Researchers are testing whether a handheld device that shines a special light on the inside of the mouth can help clinicians spot suspicious areas that might be precancerous or cancerous. The study will have three dentists with different levels of experience examine 200 adults, i…

This study is adapting and testing a French version of the Athletic Disordered Eating (ADE) scale, a 17-question screening tool designed specifically for athletes. Researchers will enroll 229 athletes aged 15 to 70 who exercise more than 6 hours per week. Participants complete th…

This study tested whether a rapid point-of-care test (Xpert® Xpress MVP) helps doctors diagnose vaginal infections more accurately than usual methods. 351 women with symptoms like discharge or itching were randomly assigned to either usual care or the rapid test. Researchers then…

This study looked at whether whole body MRI can accurately diagnose inflammatory myopathies—a group of muscle diseases causing weakness and damage. Researchers compared MRI results with muscle biopsies in 139 people suspected of having these conditions. If MRI proves reliable, it…

This study tested whether an artificial intelligence tool called Legit Health Plus can help doctors track the severity of chronic skin conditions like acne, psoriasis, and eczema from a distance. 160 participants used a smartphone app for 6 months to take photos of their skin and…

This completed study tested whether an AI device could help 16 doctors (10 general practitioners and 6 dermatologists) more accurately diagnose 13 different skin conditions, including melanoma, psoriasis, and acne. The doctors reviewed 29 medical images, first giving a diagnosis …

This study tested whether an artificial intelligence (AI) tool could help primary care doctors diagnose skin conditions more accurately. Nine doctors reviewed 30 images of various skin problems, first giving their own diagnosis and then a final diagnosis after seeing the AI's sug…

This study tested a device called SUDOSCAN, which measures sweat function in just two minutes, to see if it can detect small fiber nerve damage in people with autoimmune diseases (like lupus or rheumatoid arthritis) or unexplained pain. Researchers enrolled 139 adults and compare…

This study tested two different skin protection products to prevent incontinence-associated dermatitis (a type of diaper rash) in elderly nursing home residents. Researchers compared a film-forming protectant and a lipophilic (oil-based) protectant against no treatment in 220 par…

This study tested a new treatment called STMC-103H in 283 newborn babies and infants who are at high risk for developing allergies (like eczema or food allergies) because of their family history. The goal was to see if the treatment is safe and can prevent these allergic conditio…

This study tested whether giving mothers a single 2-gram dose of the antibiotic azithromycin during labour could reduce the risk of skin and soft tissue infections in their babies during the first three months of life. Over 2,000 pregnant women in Fiji took part, receiving either…

This Phase 3 trial tests a new gel (N-Acetyl-GED-0507-34-LEVO) applied once daily for 12 weeks to reduce acne lesions on the face and trunk. About 400 participants will be randomly assigned to receive either the active gel or a placebo. Researchers will measure changes in lesion …

This Phase 3 trial tests a new gel called N-Acetyl-GED-0507-34-LEVO for acne vulgaris. About 400 people will apply the gel or a placebo daily for 12 weeks. Researchers will count pimples and rate skin clarity to see if the gel works better than placebo.

Researchers are testing whether an investigational eyelid emollient balm improves comfort and tolerance when used with tacrolimus 0.1% ointment in adults with atopic eyelid dermatitis. The study enrolls 33 people aged 18 to 65 with eczema on both eyelids. Each person applies the …

This Phase 3 trial tests whether dupilumab (Dupixent) can reduce severe itching in adults with lichen simplex chronicus, a skin condition causing intense itch. 142 participants will receive either dupilumab or placebo injections for 24 weeks. The main goal is to see if more peopl…

This Phase 3 trial tests whether dupilumab (Dupixent) injections can reduce severe itching in adults with lichen simplex chronicus, a skin condition causing intense, persistent itch. About 138 participants will receive either dupilumab or a placebo for 24 weeks. The main goal is …

This early-stage study tests a new drug called ATTO1310 to see if it is safe and how the body processes it. It includes healthy adults, people with atopic dermatitis (eczema), and those with long-term itching. Participants receive either the drug or a placebo and are monitored fo…

This early-stage study tests a new drug called ATTO-3712 in healthy adults and people with atopic dermatitis (eczema). The main goal is to check if the drug is safe and how the body processes it. Participants receive either the drug or a placebo and are monitored with clinic visi…

Researchers compare alpha hydroxy acids, both with and without nanocarriers, against a standard calcipotriol plus betamethasone ointment for plaque psoriasis. The trial enrolls 80 adults with mild to moderate psoriasis who have not used psoriasis therapy for two months. Participa…

This study follows about 200 people aged 12 and older in Canada who are using a prescription gel containing clindamycin, adapalene, and benzoyl peroxide for acne. Researchers want to see how satisfied patients are, how well they stick to the treatment, and how it affects their qu…

Researchers are testing whether nicotinamide riboside, a form of vitamin B3 sold as a supplement, can reduce immune system activation in people with mild to moderate psoriasis. The trial enrolls adults aged 18 to 80 who are not on biologic therapy. Participants take either the su…

This Phase 3 trial tests whether wearing a hydrogel bandage on the skin of the head and neck during radiation therapy can reduce pain and skin irritation in people with head and neck cancer. About 130 participants will either wear the bandage for at least 5 hours a day during tre…

This study evaluates a new dermocosmetic cream containing 15% azelaic acid in people with mild-to-moderate acne. Researchers will observe how well the cream reduces acne lesions and improves skin discoloration, and how well it is tolerated, compared to standard treatments like or…

This Phase 3 trial tested a cream containing ruxolitinib in 204 adults with prurigo nodularis, a skin condition causing intense itching and hard bumps. Participants applied the cream twice daily for 12 weeks. The main goal was to see if it reduced itch by at least 4 points on a 0…

This trial tests whether a cream made with mushroom extracts can help protect the skin of women undergoing radiation therapy for breast cancer. Participants use the cream or a standard moisturizer on the treated breast twice daily, starting before radiation and continuing for a m…

This trial is testing whether a bio-natural moisturizing cream, called SaaTwae, can safely ease symptoms of mild-to-moderate atopic dermatitis (eczema) in children and adults. Participants will apply the cream or a placebo to affected skin twice daily, and researchers will track …

This trial tests a topical serum containing 0.5% salicylic acid in adults with acne-prone skin. Over eight weeks, participants apply the serum as directed and report changes in acne symptoms, skin texture, tone, and more. The study uses questionnaires and expert photo grading to …

This trial tests whether adding a glutathione gel to microneedling improves the lightening of dark gums compared to microneedling alone. Fifteen healthy adults with gum pigmentation will receive both treatments on different sides of their mouth to compare results. The study measu…

This study tested a drug called sebetralstat in 36 children aged 2 to 11 with hereditary angioedema (HAE) types I or II, a condition that causes sudden, painful swelling. The goal was to see if the drug is safe and how well it works to relieve attacks. The trial was open-label, m…

This trial tests whether a cream containing hyaluronic acid, peptides, and plant extracts can improve skin barrier function and ease symptoms in people with atopic dermatitis (eczema). Participants, aged 2 and older, will use the cream alongside their usual topical corticosteroid…

This study tests a moisturizing lotion made with Edelweiss extract, macadamia oil, and shea butter in 15 adults with mild-to-moderate eczema. Over 4 weeks, doctors will check skin redness, dryness, and severity, and participants will report any side effects. The goal is to see if…

This study tests whether a special antioxidant moisturizing serum can improve mild to moderate seborrheic dermatitis on the face. Researchers will apply the serum to one side of the face and a control product to the other side for 4 weeks in 13 adults. The goal is to see if the s…

This study tested a daily tablet called NatureU Histra Disslove in 19 adults with chronic hives. Participants took one tablet before a main meal for 28 days. The study measured how well the tablet controlled hives, reduced symptoms, and improved quality of life. Results showed ch…

This study tests whether a daily supplement called NPQ Plus can improve skin health, antioxidant status, fatigue, and well-being in healthy adults with minor skin concerns like dryness or itchiness. The supplement contains polyphenols, NMN, PQQ, CoQ10, and minerals. Participants …

This study looked at two treatments for oral lichen planus, a chronic mouth condition that can cause pain and change how food tastes. Researchers compared a light-based treatment (photodynamic therapy) with steroid cream in 65 adults. They measured taste ability, pain, and lesion…

This trial tests whether myofascial release techniques—a form of self-massage using rolling tools—can improve shoulder and elbow mobility, strength, and performance in volleyball players. Over eight weeks, participants perform the techniques three times per week with a physiother…

This early-stage trial tests whether HL-300 ointment is safe and tolerable when applied to the skin of healthy adult volunteers. Researchers will give single or multiple doses of the ointment or a placebo to 36 participants aged 18 to 45 in China. The study monitors for side effe…

This pilot study tests whether a special cream (KeraStat) and a mobile app (MyCap) can help manage skin rashes caused by radiation therapy in head and neck cancer patients. Sixteen participants will apply the cream at least twice daily during radiation and use the app to report t…

This study tested whether a supplement containing L-histidine, along with a topical oil or lotion and unscented soap, could improve mild-to-moderate eczema in children. Forty children ages 1 to 12 were split into two groups: one received a powder supplement and the other a gummy …

This phase 2 trial tested a gel called HY209 on 210 adults with mild to moderate atopic dermatitis (eczema). The study compared different strengths of the gel to a placebo to see if it could reduce skin redness, itching, and rash. Results will show whether the gel is safe and eff…

This study tested a self-guided online program for people with psoriasis. 348 adults were split into two groups: one got the app plus their regular treatment, the other got regular treatment alone. The main goal was to see if the app improved quality of life over 12 months.

This study tested whether a silicone barrier spray works as well as a standard zinc oxide ointment for treating mild skin rash caused by incontinence in nursing home residents. Forty participants received one of the two treatments as part of a regular skin care routine. Researche…

This study tested a preventive skin care routine in 14 children (ages 6 months to 18 years) with brain tumors who were receiving targeted therapy (BRAF, MEK, or Pan-RAF inhibitors). The goal was to see if gentle skin care and sun protection could reduce or prevent skin reactions …

This study tests whether a daily skincare routine using Cetaphil cleansers and moisturizers can improve skin symptoms and quality of life for people with mild-to-severe plaque psoriasis. Participants apply the products to one side of their body while continuing their usual prescr…

This study tested whether the drug deucravacitinib can improve quality of life for adults with moderate-to-severe plaque psoriasis. 180 participants received either the drug or a placebo. The main goal was to see if more people on the drug reported no or minimal impact of their s…

This completed Phase 4 study tested multiple doses of Qwo, a drug made from bacterial enzymes, for treating mild to moderate cellulite in adult women. Five participants received injections in their buttocks and thighs over three sessions. The goal was to see if the treatment impr…

This study tested whether people with diabetic foot ulcers can safely change their own dressings compared to having a nurse do it. Sixty adults with mild to moderate ulcers were randomly assigned to either self-dressing or nurse-led dressing. The researchers tracked healing time,…

This study tested a cream containing ruxolitinib on 241 adults with moderate atopic dermatitis (eczema) who had not gotten better with standard steroid creams. The goal was to see if the cream could improve skin clearing and reduce itching. The trial is now complete, and results …

This early-phase study tested a medicated foam called ARQ-154 (roflumilast) in 22 children aged 2 to 12 with scalp and body psoriasis. The goal was to see how much of the drug enters the bloodstream and whether it is safe. Researchers monitored side effects and skin reactions ove…

This pilot study tested whether adding group psychotherapy to standard care can help adults with moderate-to-severe atopic dermatitis (eczema). Thirty-two participants were assigned to either standard care alone, standard care plus stress management and resilience training, or st…

This study tested a laser device (NIRA Laser M2.1) on 120 adults aged 35 and older to see if it could safely reduce full-face wrinkles. Some participants also used a topical cream after the laser. Wrinkle improvement was judged by experts looking at before-and-after photos, and p…

This study looked at whether adding vitamin K2 to standard treatment could improve symptoms in children aged 6–12 with moderate-to-severe atopic dermatitis (eczema). For 12 weeks, 100 children received either vitamin K2 or a placebo alongside their usual care. The main goal was t…

This study tested whether a cosmetic shampoo can reduce dandruff and scalp flaking in adults with mild to moderate seborrheic dermatitis. 90 participants used the test shampoo, a standard medicated shampoo, or a regular cosmetic shampoo for 4 weeks. Researchers measured dandruff …

This completed study tested a moisturizing medical device called RL3020-DP0364 (Dexeryl) in 40 adults with stable mild plaque psoriasis, dry skin, and itching. Participants applied the cream to their whole body (except head) for about a month. The main goal was to see if it reduc…

This study tested a special cream made with ozonated oils and biotin for women with oily scalp. 66 women aged 18-40 used the cream or a placebo every night for 6 weeks. The active cream reduced scalp oil by 28%, compared to 10% for placebo, and was well-tolerated with only mild i…

This study looked at whether taking creatine and coenzyme Q10 supplements, along with exercise, could help children with juvenile myositis (a disease that causes muscle weakness and fatigue). Fifteen children aged 7 to 18 took part. The goal was to see if these supplements could …

This study compared a new tapinarof cream to an already-approved one (Vtama®) for treating plaque psoriasis, a skin condition causing red, scaly patches. 575 adults with mild to moderate psoriasis used one of the creams or a placebo for a set time. The goal was to see if the new …

This study tested a home-use light device and special mouth rinse to help people with oral lichen planus, a painful mouth condition. Thirteen participants used the device daily for a year alongside standard care. The goal was to see if it could reduce pain and inflammation better…

This study tested a silver-plated wound dressing (Silverlon) in 17 breast cancer patients receiving radiation therapy. The goal was to see if the dressing could reduce the severity of acute radiation dermatitis, a common skin reaction that causes redness, peeling, and pain. Patie…

This Phase 2 trial tested a cream called VC005 on 118 adults with mild to moderate atopic dermatitis (eczema). The study compared the cream to a placebo to see if it safely reduces eczema symptoms like itching and skin redness. Results will help decide if larger studies are warra…

This study tested a special cream containing a butyrate releaser (a substance that helps the skin barrier) in 100 children aged 6-36 months with eczema. The cream was compared to a standard moisturizer over 12 weeks. The goal was to see if it could reduce eczema severity and impr…

This study tested an experimental oral drug called LNK01001 against a placebo in 356 adults with moderate to severe atopic dermatitis (eczema) who had not responded well to creams or other treatments. The goal was to see if the drug could improve skin clearing and reduce itching …

This study looked at how a prescription lotion (IDP-118) works in children aged 4 to 16 with moderate to severe plaque psoriasis. Researchers measured how much of the drug enters the bloodstream and whether it affects the body's stress hormone system (HPA axis). The goal was to c…

This study tested whether caffeine helps elite weightlifters perform better in competition. Fourteen athletes took either caffeine or a placebo before a simulated weightlifting meet. The results suggest caffeine can provide a small performance boost, but the effect is modest and …

This study tested whether a nano-crystalline silver dressing helps gums heal faster and with less pain after surgical removal of dark gum pigmentation. Twelve adults with moderate to severe gum pigmentation had the surgery, and the silver dressing was compared to a standard dress…

This study looked at whether intermittent fasting (eating only during certain hours) can reduce disease severity and improve quality of life for people with psoriasis and psoriatic arthritis. Sixty overweight adults were randomly assigned to either follow an intermittent fasting …

This study tested a new ointment called CGB-500, which contains the drug tofacitinib, for treating eczema (atopic dermatitis) in 180 people aged 12 and older. Participants applied the ointment or a placebo daily for 8 weeks. The goal was to see if it safely reduces skin redness, …

This study looked at whether taking sodium bicarbonate (baking soda) before exercise helps well-trained cyclists perform better during a long, intense ride. Nineteen athletes did two lab sessions: three hours of moderate cycling followed by a max-effort time trial. They took eith…

This study tested two different exercise programs in 28 children and teens with rheumatic diseases like juvenile arthritis and familial Mediterranean fever. One program used external focus (thinking about the movement's effect), the other used internal focus (thinking about the b…

This Phase 3 study tested the drug tildrakizumab in 99 adults with moderate to severe nail psoriasis. Participants received either the drug or a placebo for 28 weeks to see if it improved nail appearance and reduced pain. The trial is complete, and results may help determine if t…

This study tested whether adding a special antioxidant pill (GLISODIN) to standard UVB light therapy helps treat vitiligo better than light therapy alone. Fifty adults with non-segmental vitiligo covering more than 5% of their body took part. The main goal was to see if the combi…

This study tested a cream made from plant compounds (total coumarins) in 88 adults with mild-to-moderate psoriasis. Participants applied the cream or a placebo for several weeks. The goal was to see if the cream safely reduces skin redness, scaling, and thickness better than a pl…

This study tested a cream paste containing pleuran (a beta-glucan from oyster mushrooms) on 110 children with diaper rash, perioral dermatitis, or neonatal pustulosis. Participants applied the cream 2-3 times daily for up to 2 weeks without other treatments. Researchers measured …

This study involved 324 adults with conditions like Crohn's disease, arthritis, or psoriasis who switched from a standard to a higher-concentration form of adalimumab (AVT-02). Researchers measured injection site pain and how well patients stuck with their treatment over 180 days…

This study tested whether a measles vaccine could help control eczema (atopic dermatitis) in adults. Researchers gave 20 adults with moderate-to-severe eczema either the measles vaccine or a placebo and tracked their symptoms for 45 days. The goal was to see if the vaccine could …

This study tested a scalp moisturizer made with celastrol and chicory root extract in 23 adults with dry, flaky scalp or dandruff. Participants applied it every night for 4 weeks. Researchers used artificial intelligence to measure changes in scalp condition. The goal was to see …

This study tested whether applying insulin directly to skin sores helps them heal faster in people with pemphigus vulgaris, a rare autoimmune blistering disease. Twenty patients each had three similar sores treated with either long-acting insulin, short-acting insulin, or a saltw…

This study tested whether a cream made from icariin, a plant compound, can improve acne and reduce acne scars. Twenty-five adults applied the cream or a control solution to their face twice daily for two months. The goal was to see if it lowers the number of pimples and scars and…

This early-stage study tested an oral medication called KT-621 in 22 adults with moderate to severe atopic dermatitis (eczema). The main goal was to check safety and how the body processes the drug. Researchers monitored side effects and drug levels in the blood, but did not meas…

This study tested an experimental drug called SCD-044 in 263 adults with moderate to severe plaque psoriasis. Participants received either the drug or a placebo to see if it could improve skin symptoms like redness and scaling. The main goal was to measure how many people achieve…

This study tested a special dressing coated with a substance that binds bacteria (DACC-coated hydrogel) to treat skin burns caused by radiation therapy in 18 women with breast cancer. The goal was to see if it could reduce pain and help heal the skin. The study is already complet…

This study tested whether a selenium gel can help treat oral lichen planus, a chronic condition that causes painful sores in the mouth. Fifty adults with the condition used either selenium gel, a standard steroid cream, or an immunosuppressant cream. The goal was to see if seleni…

This Phase 3 trial tested a cream called ruxolitinib (also known as Opzelura) in 190 adults with prurigo nodularis, a skin condition causing intense itching and hard bumps. Participants applied the cream twice daily for 12 weeks. The main goal was to see if it could reduce itch b…

This study tested an oral medication called deucrictibant for quickly relieving swelling and pain attacks in people with hereditary angioedema (HAE) types I and II. 74 adults received either one of three doses of the drug or a placebo during an attack. The main goal was to see if…

This study tested a behavioral therapy called EMD-U in 96 adults with atopic dermatitis or prurigo nodularis who had a strong urge to scratch. The therapy involves focusing on the itchy spot while moving the eyes, repeated until the urge fades. Researchers compared EMD-U plus usu…

This study tested an experimental drug called BSI-045B in 22 adults with moderate to severe atopic dermatitis (eczema). Participants received injections weekly for 4 weeks, then every 2 weeks up to 24 weeks. The main goals were to see if the drug safely reduces eczema severity by…

This study tested a cream called MC2-25 to see if it can safely reduce itching in women with vulvar lichen sclerosus, a skin condition that causes discomfort. 33 women used either the active cream or a placebo for 12 weeks. The main goal was to measure how much the worst itching …

This study looked at whether a morphine gel can help with pain from severe radiation-induced skin irritation (radiodermatitis) in the perineal area. Researchers reviewed records of 17 patients who used the gel. The goal was to see if pain decreased and if it helped avoid breaks i…

This study followed 291 adults with mild-to-moderate scalp psoriasis who were prescribed a cream containing calcipotriene and betamethasone (Wynzora®). Researchers measured how satisfied patients were with the treatment, its effect on quality of life, and how well it worked in re…

This study tested whether giving a steroid (cortancyl) along with an antihistamine (levocetirizine) is better than the antihistamine alone for treating sudden hives in the emergency department. 137 adults with acute urticaria (with or without mild angioedema) were enrolled. The m…

This study tested two skin treatments—a hydrogel dressing and a water spray—for women with breast cancer who developed skin irritation from radiotherapy. The goal was to see which one better prevented treatment delays or the need to switch care. 278 women with mild to moderate sk…

This study looked at whether people with mild-to-moderate psoriasis prefer using Wynzora cream over Enstilar foam. Thirty adults who had previously used Enstilar foam tried Wynzora cream for four weeks. Researchers used questionnaires to measure preference, treatment satisfaction…

This study investigated whether environmental exposures during military service increase the risk of developing myositis, a rare autoimmune disease that attacks muscles. Researchers compared 37 military personnel with and without myositis using questionnaires and blood samples. N…

This completed study looked at 386 adults with psoriasis to understand how skin inflammation might be linked to heart and blood vessel diseases. Participants had up to seven visits over four years, including blood tests, heart scans, and optional skin biopsies. The goal was to se…

This study follows up to 5,000 people with autoinflammatory diseases (like NOMID, CANDLE, and juvenile dermatomyositis) and their healthy relatives. Researchers will collect medical history, blood samples, and imaging over 2-5 day visits to learn how these diseases work and find …

This study looks at people who have severe allergic reactions (anaphylaxis), especially when the cause is unknown. Researchers will do blood tests and bone marrow biopsies to find genetic or molecular clues. The goal is to understand what goes wrong in the body, not to test a new…

Researchers are studying whether a non-invasive skin imaging technique called reflectance confocal microscopy can predict how well people with moderate to severe atopic dermatitis respond to dupilumab. The trial enrolls 40 participants aged 6 months and older who are starting dup…

This completed study followed 945 people, mostly children and young adults with severe eczema or related allergic conditions, along with their relatives. Researchers observed how these diseases progress over up to a year, using tests like allergy skin pricks, blood draws, and lun…

This study looks at how oral isotretinoin, a common acne treatment, affects the surface of the eye and the meibomian glands, which produce the oily layer of tears. Researchers will measure tear film stability, gland structure, and dry eye symptoms in 60 acne patients before and a…

This study looks at how a new medicine (PF-08049820) is processed by the body when taken alone or with another drug (rabeprazole). It involves 18 healthy Chinese adults aged 18-65. Participants take both medicines by mouth, and blood samples are collected to measure drug levels. …

This study aims to adapt the Menstrual Cycle Knowledge Questionnaire (MCKQ) into Turkish and check whether it is a valid and reliable tool for female athletes. Researchers will ask 120 women aged 16 to 35 who are licensed athletes to fill out the questionnaire, along with other s…

This study looks at how a new medicine called PF-08049820 changes the way birth control pills, a sedative, and a blood thinner move through the body. It involves 16 healthy adult women who will take the drugs alone and then with PF-08049820. The results will help plan future stud…

This study looked at 47 people with bullous pemphigoid, a blistering skin condition, who were treated with high-dose topical corticosteroids (clobetasol propionate) for 6 months. Researchers measured bone mineral density at the start, at 3 months, and at 6 months to see if the tr…

This early-stage study tests the safety of PF-08049820, a medicine being developed for eczema (atopic dermatitis), in about 71 healthy adults. Participants will take single or multiple doses of the drug or a placebo, and researchers will monitor how the body processes it and whet…

This study looks at whether a common light treatment for vitiligo changes certain proteins in the skin. Researchers will measure two markers, CD63 and CD9, in skin samples from 20 people with vitiligo before and after three months of narrow-band ultraviolet B (NB-UVB) therapy. Th…

This trial tests two common warm-up techniques in amateur athletes aged 18 to 30. After a short cycling warm-up, participants either roll their hamstrings with a foam roller or perform PNF stretching. Researchers measure hamstring flexibility, leg strength, vertical jump, and pai…

This study looked at 719 people, including patients with autoimmune connective tissue diseases like myositis, their blood relatives, and healthy volunteers. Researchers collected blood samples and medical histories to find genetic and environmental factors that may trigger these …

This study investigates whether compounds found in ultra-processed foods, like advanced glycation end products (AGEs), might play a role in childhood eczema, also known as atopic dermatitis. Researchers will compare the diets of 100 children aged 6 months to 10 years, half with e…

This early-stage study tests a new drug called SHR-1819 in 160 healthy adults to see how it enters the body when given with different injection devices. The goal is to compare the drug levels and safety between devices, not to treat any disease. Participants must be 18-55 years o…

This study tested whether full-body suits made with far-infrared (FIR) emitting fibers affect body temperature, heart rate, oxygen use, and power output in young competitive cyclists. Nine cyclists rode a stationary bike for 40 minutes at a steady pace, then did a 5-second sprint…

This study looked at how well vaccines work in adults with moderate-to-severe eczema who are taking amlitelimab, an experimental drug. About 224 participants received either amlitelimab or a placebo along with tetanus and pneumonia vaccines. The goal was to see if the drug change…

This study looks at whether Aquacel, a silver-containing wound dressing used after hip or knee replacement surgery, can cause allergic contact dermatitis—a type of skin rash. Researchers will compare patients having their first joint replacement with those who had a previous join…

This study looks at how athletes who regularly lose and regain weight to meet competition categories experience changes in metabolism, body temperature, and body composition. Researchers will track 48 athletes through periods of weight maintenance, loss, and regain, using body te…

This pilot study tested whether time-restricted feeding (eating all daily calories between 8am and 2pm, then fasting for 18 hours) could reduce inflammation in men with mild to moderate psoriasis. 27 participants (including healthy volunteers) stayed at the clinic for 4.5 days, w…

This study surveys medical students to understand their attitudes toward tattoos and piercings and measure their awareness of related skin risks, such as infections, allergic reactions, and scarring. Researchers aim to see if students have adequate knowledge and how their views d…

This observational study in children and adolescents with tinea capitis (a scalp fungal infection) investigates whether changes seen under a trichoscope—a special microscope for hair and scalp—can predict when the infection is cured. Participants receive the antifungal drug terbi…

This study looked at whether rocatinlimab, a drug for moderate-to-severe eczema, changes how well vaccines work. About 221 adults with eczema received either the drug or a placebo, then got tetanus and meningococcal vaccines. The goal was to see if the drug lowers the body's abil…

This study looks back at medical records of adults who were sent home from the emergency department to receive hospital-level care for common infections like pneumonia, urinary tract infections, or skin infections. The goal is to understand why some of these patients end up needi…

This study looks at the features of psoriasis and how the skin condition impacts the quality of life of patients visiting Tanta University Hospitals. Researchers will collect information from 170 adults with psoriasis to understand the disease's effects on their daily lives. The …

This pilot study tests whether applying over-the-counter moisturizers (CeraVe or Vaseline) daily for 4 weeks can reduce inflammation in adults aged 70 and older with dry skin. Researchers will measure skin barrier function, blood markers of inflammation, and skin microbes. The ma…

This study looks at children with eczema (atopic dermatitis) that is not well controlled by prescription creams or for whom such creams are not advised. Researchers are collecting blood and cheek swab samples to find biological markers (biomarkers) that may be linked to how the d…

This study looks at how isotretinoin, a vitamin A-based acne medication, affects eye structures and tear production in people with severe cystic acne. Participants receive standard treatment and undergo eye exams, including dry eye tests and advanced imaging, before and during th…

This study looked at how the drug adalimumab affects gene activity in the skin of people with chronic plaque psoriasis. Researchers compared skin samples from normal, non-lesional, and lesional areas before and after treatment. The goal was to understand the immune changes that h…

This study looked at whether doing drop jumps during warm-up helps young basketball players jump higher, sprint faster, and land more stably. Twenty-two athletes were split into two groups: one added drop jumps to their warm-up for 8 weeks, the other did not. Researchers measured…

This study looked at whether adding strength training to regular cycling workouts helps competitive cyclists improve performance and muscle function. Twenty-four male cyclists either did strength training plus endurance training or just endurance training for 10 weeks. Researcher…

This study tested whether AI-generated educational material on acne could teach medical students as well as standard human-written material. 190 first- and second-year medical students were split into three groups: one read AI-generated content, one read content from the Turkish …

This study looks at how taking VC005 tablets with or without food changes the drug's levels in the blood. It involves 30 healthy adults aged 18 to 45. The goal is to gather information to help design future studies for atopic dermatitis (eczema). Participants will take the drug t…

This completed study looked at scalp ringworm, a common fungal infection in children, across 11 French centers in 2023. Researchers collected 701 fungal samples to identify the species and test their sensitivity to common antifungal drugs. The goal was to understand which fungi c…

This study looked at the genes in the skin of 433 people with eczema (atopic dermatitis) to find patterns that separate mild from severe cases. Researchers collected skin samples and tracked how these patterns changed with standard treatments like steroid creams and dupilumab. Th…

This study looked at how people with autoimmune diseases like multiple sclerosis or blistering skin conditions respond to COVID-19 vaccines while on B-cell depleting therapies. Researchers measured antibody levels and T-cell activity over time to understand vaccine effectiveness …

This study looked at 271 hospital patients with incontinence to find out which factors most strongly predict a common skin problem called incontinence-associated dermatitis (IAD). Researchers tracked things like age, stool consistency, and mobility, checking patients' skin daily.…

This study tested whether 40 sessions of hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) could improve aerobic and anaerobic fitness in healthy athletes. 59 participants, aged 18-25 or 40-50, underwent either real or sham treatment over two months. Rese…

This study looked at how adults with moderate-to-severe atopic dermatitis (eczema) that is controlled by systemic treatments (like pills or injections) use and feel about a cosmetic moisturizer called RV4427C WM0071. The goal was to understand their needs, expectations, and how s…

This study looked at 80 adults with moderate-to-severe atopic dermatitis (eczema) whose condition is controlled by systemic treatments. Researchers wanted to understand how these patients use moisturizers and what they expect from them. Participants filled out questionnaires abou…

This completed study looked at whether lichen planus, a chronic inflammatory condition, affects smell and taste. 88 adults (patients and healthy controls) took smell and taste tests and had oral and nasal exams. The goal was to see if mucosal involvement is linked to sensory chan…

This study looked at 100 adults with atopic dermatitis (eczema) who were prescribed tralokinumab. Researchers tracked how many developed eye problems like conjunctivitis within 4 months of starting the drug. The goal was to better understand these side effects in real-world use, …

This study looked at 134 competitive runners to see if advanced footwear technology (AFT) — the springy, carbon-fiber shoes many elite athletes wear — is linked to more muscle and tendon injuries. Researchers surveyed athletes about their training habits and injury history over t…

This completed study looked at hand and wrist injuries in professional hockey players in the Swedish Hockey League over three seasons. Researchers analyzed injury data from about 2,300 games to understand what types of injuries happen, when they occur, and which players are most …

This pilot study tested a nurse-led educational program for people with psoriasis. Twenty-four participants received extra education sessions over six weeks, alongside standard care. The goal was to see if the program was feasible and could improve disease knowledge, self-managem…

This completed French survey of 300 hereditary angioedema (HAE) patients and their caregivers aimed to understand the challenges of using on-demand treatments for HAE attacks. Researchers collected data on attack frequency, severity, treatment delays, hospitalizations, and the fi…

This study examined how the drug omalizumab is prescribed in real-world practice for adults with chronic urticaria (long-term hives) in China. Researchers analyzed electronic health records from over 3,400 patients to see what doses were commonly used. The goal was to understand …

This early-stage study tested a single dose of the experimental antibody SM17 in 30 healthy Chinese adults to see if it is safe and how the body processes it. The study did not aim to treat any disease. Results will help plan future trials for conditions like eczema, asthma, and …

This study looked at skin samples from 170 people with psoriasis, atopic dermatitis (eczema), or healthy skin to understand how a protein called Lyn is involved in inflammation. Researchers measured Lyn activity and related enzymes in both affected and unaffected skin. The goal w…

This completed Italian study looked at over 1,300 people with scabies to see how often the first treatment cured them. Researchers also tracked how many scabies cases occurred over three years and analyzed patterns by age and ethnicity. The study did not test a new drug but colle…

This completed study looked at 52 adults with plaque psoriasis who had been on biologic drugs for at least one year. Researchers used questionnaires to measure treatment satisfaction, quality of life, depression, and personality type. The goal was to find out which clinical and p…

This study explored whether the Epstein-Barr virus (EBV) contributes to inflammation in oral lichen planus, a chronic mouth condition that can be painful. Researchers measured levels of EBV genetic material in 13 adults with the atrophic or erosive form of the disease. The goal w…

This study tested a new questionnaire called DermCLCI-p to see if it accurately measures the long-term life impacts of moderate-to-severe psoriasis. 154 adults starting the medication risankizumab filled out the 30-question survey over 28 weeks. The goal was to validate the tool …

This study looked at how standing on a vibrating platform affects spinal reflexes in 15 healthy adults. Participants stood in different positions with or without vibration while researchers measured electrical signals from a leg muscle. The goal was to understand how vibration ch…

This study looked at a new way to measure muscle function in people with inflammatory myopathies (diseases that cause muscle weakness). Researchers compared a simple test called the Myositis Functional Index-3 with advanced computerised muscle testing. They also tested whether a …

This early-phase study looked at whether a protein from the Maackia amurensis seed (MASL) can target a receptor called podoplanin found on oral cancer and precancerous cells. Researchers measured how much of this receptor was present in tissue samples from 18 adults with suspicio…

This study compares skin samples from 20 people with vitiligo and 20 healthy volunteers to understand why certain body areas (like the face) repigment well while others (like hands and feet) do not. Researchers will analyze gene activity in skin from five different body sites. Th…

This study followed 487 pregnant women in Shanghai to see if key nutrients like folate and vitamin D affect the chance of their baby developing eczema (atopic dermatitis) by 6 months old. Researchers measured nutrient levels in the mothers' blood and checked babies for eczema usi…

This study looked at the types of fungi living on the head and neck skin of 30 adults with eczema (atopic dermatitis) compared to healthy volunteers. The goal was to understand if differences in the fungal community are linked to eczema in these areas. Researchers used advanced l…

This study looked at whether the drug dupilumab, used for eczema or asthma, is safe during pregnancy. Researchers compared 581 pregnant women who took dupilumab with those who did not. They tracked birth defects, miscarriages, and infant health up to one year old to see if the dr…

This study tested whether an artificial intelligence (AI) tool could help doctors diagnose rare and tricky skin conditions like generalized pustular psoriasis (GPP). Fifteen doctors, including both general practitioners and dermatologists, looked at 100 skin images. They first ga…

This study tested whether using a laser for oral biopsies causes less pain and heals better than the standard punch scalpel in people with oral lichen planus. 112 adults were randomly assigned to one of the two methods. Researchers measured wound healing and discomfort after the …

This study aimed to create and test a decision aid for people with psoriasis or psoriatic arthritis who are starting or switching treatments. Researchers worked with 37 patients and their doctors to design a tool that supports shared decision-making. The goal was to help patients…

This study followed over 2,300 adults with moderate to severe plaque psoriasis to see how safe and effective secukinumab is in everyday medical practice. Researchers recorded side effects and how well the drug cleared skin symptoms. The goal was to gather real-world evidence, not…

This study looked at whether specially engineered versions of a natural immune protein (IL-2) can selectively boost regulatory T cells, which help calm the immune system. Researchers took blood samples from 67 people with various autoimmune or inflammatory conditions and tested t…

This study tested whether coaching sessions are practical for young people with rheumatic diseases moving from pediatric to adult care. 26 participants received up to 8 coaching sessions covering self-advocacy, medication management, and future planning. The main goal was to see …

This completed registry study in Japan looked at how doctors treat palmoplantar pustulosis (PPP), a skin condition causing pus-filled blisters on hands and feet. Researchers collected data from 276 patients' medical records and clinic visits to understand which treatments are use…

This study looked at 48 adults with pemphigus, a rare blistering skin disease, to understand what makes them feel vulnerable during their illness. Researchers used interviews and questionnaires to explore factors like misdiagnosis, differences in how patients and doctors see dise…

This study measured fluid retention in 30 people with bullous pemphigoid who were treated with a strong steroid cream (clobetasol propionate). Researchers used bioimpedance to track changes in body water over 30 days. The goal was to understand if the cream causes fluid buildup a…

This pilot study tested whether it is possible to collect and analyze small RNA molecules from a person's breath. Researchers took breath samples from 25 volunteers (healthy people and a few with lung disease) at rest and after intense exercise. They successfully extracted and se…

This study looked at gene activity in immune cells from 30 people with hereditary angioedema and healthy volunteers. The goal was to see if certain receptors on monocytes are linked to inflammation and blood vessel problems. No treatment was given; the study was purely observatio…

This study tested whether wearing special stroboscopic glasses during volleyball drills could improve how players' brains and bodies react. 42 female volleyball players aged 10-16, from beginners to elite, took part. They did 8 weeks of extra drills with or without the glasses. R…

This completed study looked at how well parents of infants with early eczema and parents of healthy infants could use a mobile-friendly platform called OneBiome. The platform gives reports on the baby's gut microbiome and eating patterns. Researchers wanted to see if parents foun…

This study followed 88 people with hereditary angioedema (HAE) types I or II who already use icatibant for sudden attacks. Participants filled out diaries for 48 hours after each attack to report symptom changes, severity, and anxiety levels. The goal was to gather real-world inf…

This study looked at fatigue in 33 adults with psoriatic arthritis or psoriasis. Researchers used questionnaires to measure tiredness and see how it relates to disease severity and treatments. The goal was to better understand fatigue and its impact on quality of life.

This early-phase study tested a single dose of the experimental drug rocatinlimab in 20 healthy Chinese adults. The main goal was to see how the drug moves through the body and whether it is safe. This is a first step toward possibly using the drug to treat atopic dermatitis (ecz…

This study looked at whether adding more legumes (like beans, lentils, and chickpeas) to a Mediterranean diet could improve hydration, heart rate balance, and swimming performance in competitive swimmers. Thirty-nine adolescent and young adult swimmers were split into groups base…

This pilot study gave 20 professional football players either a single high dose of vitamin D or a placebo before a match. Researchers measured how vitamin D levels changed in their blood. The goal was to see how exercise affects vitamin D metabolism, not to treat any disease.

This study looked at how staphylococcus bacteria on the skin affect inflammation and immune responses in people with moderate to severe atopic dermatitis (eczema). Researchers took skin biopsies and blood samples from 41 adults to measure bacterial toxins and immune cell activity…

This study looked at immune cells in the blood of 15 adults with seborrheic dermatitis (a chronic, flaky skin condition) and 15 healthy people. Researchers measured different types of immune cells and chemicals to see if there are differences between the two groups. They also ask…

This study looked at how often doctors increase the dose or give Xolair more frequently for people with chronic hives. Researchers followed 163 adults for 3 months to see how many needed a stronger treatment plan. The goal was to understand real-world use, not to test a new drug.

This study looked at how skin blood flow and nerve sensitivity differ in psoriasis plaques compared to healthy skin. Twenty adults with psoriasis on their back received mild electrical currents to deliver vasodilators (acetylcholine, sodium nitroprussiate, or plain water) into bo…

This study examined how the COVID-19 pandemic impacted skin allergy visits among healthcare workers. Researchers analyzed records from 341 healthcare workers who visited skin clinics before and after the pandemic. The goal was to understand if increased use of masks, gloves, and …

This completed Phase 1 study tested how the psoriasis drug Hemay005 is processed by the body in people with mild or moderate kidney impairment compared to those with normal kidneys. 26 adults took a single dose, and researchers measured drug levels in the blood to see if kidney f…

This study looked at how different music volumes affect balance in athletes. 48 healthy athletes listened to soft, medium, and loud music while standing on a virtual reality balance system. The goal was to see if sound intensity changes how well they can keep steady.

This study looked at how breathing in simulated wildfire smoke for just one hour affects healthy adults. Researchers measured a blood marker called p-tau, which is linked to memory problems, and tested thinking skills before and after exposure. The goal was to see if short-term s…

This completed study followed 127 adults with moderate to severe plaque psoriasis, psoriatic arthritis, ankylosing spondylitis, or non-radiographic axial spondyloarthritis who were already taking or starting secukinumab. Researchers observed them for two years to see how long the…

This study translated an English questionnaire into Turkish to help athletes with low back pain measure how their pain affects sports and daily activities. 120 Turkish athletes with low back pain filled out three questionnaires. The goal was to make sure the Turkish version is ac…

This study followed 198 runners in the 2015 Ultra-Trail Mont-Blanc to see if drinking only when thirsty ("at thirst") keeps blood sodium levels more stable compared to other drinking plans. The goal is to understand how hydration affects health during extreme endurance events. Re…

This study followed 461 children whose mothers took a special nutritional drink before and during pregnancy. Researchers want to understand how parents' diet, lifestyle, and metabolism influence child growth, thinking skills, and overall well-being. The goal is to identify factor…

This study measured how often sleep disturbances occur in people with bullous pemphigoid, a blistering skin condition that mostly affects older adults. Researchers compared 122 patients to healthy volunteers using a simple insomnia questionnaire. The goal was to understand if sle…

This study looked at how dupilumab, an injectable eczema drug, changes nerve fibers in the skin of 54 adults with moderate-to-severe atopic dermatitis and chronic itching. Researchers took skin biopsies to measure nerve density and branching before and after treatment. The goal w…

This completed Phase 1 trial in 18 healthy women aged 18–40 tested whether taking the experimental psoriasis drug HS-10374 changes how the body absorbs and clears the birth control pill Yasmin. Participants took Yasmin alone and then again after a course of HS-10374. Researchers …

This completed study looked at how a common skin bacterium, Staphylococcus aureus, might cause eczema flares in people with atopic dermatitis. Researchers applied patches containing the bacteria to the skin of 7 participants (both with and without eczema) and measured immune resp…