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One pill could end sleeping sickness: new trial shows promise

NCT ID NCT03087955

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 32 times

Summary

This study tested a single-dose pill called acoziborole for sleeping sickness, a deadly parasitic disease. 208 adults with early or late-stage disease took three tablets once and were followed for 18 months. The goal was to see if the pill could cure the infection without the need for long-term medication.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Centre de Traitement de Kimpese

    Kimpese, Bas-Congo Province, Democratic Republic of the Congo

  • Centre de Traitement de Nkara

    Nkara, Bandundu, Democratic Republic of the Congo

  • Centre de Traitement de la THA de Dubreka

    Dubréka, Dubreka, Guinea

  • Hopital Général de Réference de Bandundu

    Bandundu Province, Democratic Republic of the Congo

  • Hôpital Général de Référence Roi Baudouin

    Kinshasa, Democratic Republic of the Congo

  • Hôpital Général de Référence de Bagata

    Bagata, Kwilu, Democratic Republic of the Congo

  • Hôpital Général de Référence de Kwamouth

    Kwamouth, Mai Ndombe, Democratic Republic of the Congo

  • Hôpital Général de Référence de Masi-Manimba

    Masi-Manimba, Kwilu, Democratic Republic of the Congo

  • Hôpital Général de Référence de Ngandajika

    Gandajika, East Kasai, Democratic Republic of the Congo

  • Hôpital Secondaire de Katanda

    Katanda, East Kasai, Democratic Republic of the Congo

  • Hôpital de Dipumba

    Mbuji-Mayi, East Kasai, Democratic Republic of the Congo

  • Hôpital de Référence d'Isangi

    Isangi, Democratic Republic of the Congo

Conditions

Explore the condition pages connected to this study.