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Cream showdown: which antifungal works best for jock itch?

NCT ID NCT07441005

Disease control Sponsor: Hayat Abad Medical Complex, Peshawar Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested two antifungal creams—oxiconazole and clotrimazole—against each other in 386 adults with jock itch (tinea cruris). The goal was to see which one better relieved itching and redness. Both creams are already used for fungal skin infections, so this trial aimed to find out if one is a better option.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Oxiconazole cream and clotrimazole cream
What this could lead to
If one cream proves more effective, it could become a preferred treatment for jock itch, offering faster relief from itching and redness.
What could go wrong
This is a very early-phase trial, so results may not be definitive. The creams are already available, so the study may not lead to a major breakthrough.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Early phase 1

The earliest testing in people: a first look at safety, in a very small group.

Participants

386 people

The number who actually took part.

Started

May 2025

Finished

Oct 2025

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 18 to 70 years of age * Both genders * Patient with diagnosis of tinea crurus as per operational definition Exclusion Criteria: * Hypersensitivity to clotrimazole or Oxiconazole * Uncontrolled diabetes * Immunosuppresion * Patient with contact dermatitis

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Conditions

The condition(s) this trial relates to.

dermatophytosis of groin and perianal area Tinea Tinea Cruris

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Tinea cruris

Contacts and locations

Locations

  • Hayatabad medal Complex

    Peshawar, KPK, 0000, Pakistan

More trials for these conditions

Other studies related to the condition(s) this trial covers.