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Morphine gel may ease radiation burn pain

NCT ID NCT07207889

Symptom relief Sponsor: Institut Curie Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether a morphine gel can help with pain from severe radiation-induced skin irritation (radiodermatitis) in the perineal area. Researchers reviewed records of 17 patients who used the gel. The goal was to see if pain decreased and if it helped avoid breaks in radiation treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
morphine gel
What this could lead to
If effective, this could offer a new way to manage severe skin pain from radiation therapy, possibly reducing the need for strong painkillers.
What could go wrong
This was a small, retrospective study with only 17 patients, so results may not apply to everyone. The gel's effectiveness is not yet proven in larger trials.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

17 people

The number who actually took part.

Started

Dec 2024

Finished

Dec 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

17 patients who received Morphine gel for the treatment of pain associated with perineal radiodermatitis over a 20-month period between July 2022 and March 2024.

Ages

18 to 100 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients 18 years and older; * Use of a local analgesic treatment based on Morphine gel for pain associated with perineal radiodermatitis. * Patients not relieved by prescribed systemic treatments (per-os or intravenous) * Patients treated with radiotherapy for a perineal tumor, whether or not associated with medical treatment such as chemotherapy. * Minimum grade of radiodermatitis: Grade II Exclusion Criteria: * Patients who have not used the prescribed morphine gel * Minor patients * Patients using morphine gel for wounds other than radiodermatitis * Patients who object to the re-use of their data

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Conditions

The condition(s) this trial relates to.

radiodermatitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dermatitis, radiation induced

Contacts and locations

Locations

  • Institut Curie

    Paris, 75248, France