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New psoriasis drug shows promise in Mid-Stage trial

NCT ID NCT04566666

Symptom relief Sponsor: Sun Pharmaceutical Industries Limited Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested an experimental drug called SCD-044 in 263 adults with moderate to severe plaque psoriasis. Participants received either the drug or a placebo to see if it could improve skin symptoms like redness and scaling. The main goal was to measure how many people achieved at least a 75% improvement in their psoriasis severity score.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

263 people

The number who actually took part.

Started

Mar 2021

Finished

Aug 2025

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Males and non-pregnant non-lactating females with a diagnosis of predominantly plaque psoriasis for ≥ 6 months as determined by subject interview and confirmation of diagnosis through physical examination by Investigator. 2. Aged at least 18 years. 3. Subjects with no history of active TB or symptoms of TB Exclusion Criteria: 1. Subjects with non-plaque forms of psoriasis-like erythrodermic psoriasis, pustular psoriasis, medication-induced, or medication exacerbated psoriasis or new-onset guttate psoriasis. 2. Subjects who have anticipated the requirement of topical therapy, phototherapy, or systemic therapy for psoriasis during the trial. 3. Subjects with history or presence of uveitis

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Conditions

The condition(s) this trial relates to.

psoriasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Moderate to severe plaque psoriasis

Contacts and locations

Locations

  • Accel Research Sites Network - Annexus Dermatology & Aestheitcs

    DeLand, Florida, 32720, United States

  • Adtremed Inc

    Tampa, Florida, 33607, United States

  • Advanced Clinical Research Institute

    Tampa, Florida, 33607, United States

  • Alliance Clinical Research of Tampa

    Tampa, Florida, 33615, United States

  • Appletreeclinics Clinical Research Centre

    Lodz, 90-309, Poland

  • Axis Clinical Trials

    Los Angeles, California, 90036, United States

  • Century Research LLC

    Miami, Florida, 33173, United States

  • Clarity Dermatology

    Castle Rock, Colorado, 80109, United States

  • ClinicMed

    Bialystok, 15879, Poland

  • Clinica Dermatologica

    San Salvador, CP 01101, El Salvador

  • Clinica Vargas

    San Salvador, CP 01101, El Salvador

  • Clinica de Dermatologia y Cirugia de Piel

    La Libertad, CP 01501, El Salvador

  • Clinical Research Centre OU

    Tartu, 50106, Estonia

  • DFW Clinical Research, LLC

    Dallas, Texas, 75234, United States

  • David Abuladze Georgian-Italian Clinic LLC

    Tbilisi, 179, Georgia

  • Direct Helpers Research Center

    Hialeah, Florida, 33012, United States

  • Dobry Lekarz' Modern Therapies Center Limited Liability Company

    Krakow, 31-011, Poland

  • EMC Medical Institute Joint Stock Company, "Certus" Private Healthcare Facility Hospital No. 1

    Poznan, 60-309, Poland

  • Emergency Cardiology Center by Academician G. Chapidze LLC

    Tbilisi, 159, Georgia

  • Evolution Clinical Trials, Inc

    Hialeah Gardens, Florida, 33016, United States

  • FXM Clinical Research Fort Lauderdale

    Fort Lauderdale, Florida, 33308, United States

  • FXM Clinical Research Miami

    Miami, Florida, 33175, United States

  • FXM Clinical Research Miramar

    Miramar, Florida, 33027, United States

  • GLOBE Clinical Research

    Kłodzko, 58-300, Poland

  • Israeli - Georgian Medical Research Clinic Helsikor LLC

    Tbilisi, 112, Georgia

  • JD Medical Group, LLC

    Miami, Florida, 33133, United States

  • LTD Aversi Clinic

    Tbilisi, 160, Georgia

  • Landa Specialist Doctor's Offices

    Krakow, 31-156, Poland

  • Malkhaz Katsiashvili Multiprofile Emergency Medicine Center LLC

    Tbilisi, 101, Georgia

  • MedOne Clinical Research, LLC

    Miami, Florida, 33145, United States

  • Metropolis Dermatology

    Los Angeles, California, 90017, United States

  • National Medical Institute of the MSWiA, Clinical Department of Dermatology

    Warsaw, 02-507, Poland

  • North Estonia Medical Centre Foundation Ltd.

    Tallinn, 13419, Estonia

  • Oracle Clinical Research

    College Park, Georgia, 30349, United States

  • Palm Beach Dermatology Group

    Delray Beach, Florida, 33484, United States

  • Physicians Research Group

    West Lafayette, Indiana, 47906, United States

  • Revival Research Corporation

    Doral, Florida, 33122, United States

  • Revival research Institute, LLC

    Troy, Michigan, 48084, United States

  • SMS Clinical Research

    Mesquite, Texas, 75149, United States

  • Skin DC Derm

    Arlington, Virginia, 22209, United States

  • Springville Dermatology/ CCT Research

    Springville, Utah, 84663, United States

  • Stride Clinical Research

    Sugar Land, Texas, 77479, United States

  • Synexus Polska Sp. z o.o. Branch in Gdansk

    Gdansk, 80-382, Poland

  • T. Joseph Raoof Md, Imc./Encino Research Center

    Encino, California, 91436, United States

  • TIM - Tbilisi Institute of Medicine LLC

    Tbilisi, 160, Georgia

  • TWOJA PRZYCHODNIA Medical Centre of Szczecin, Twoja Przychodnia SCM

    Szczecin, 71-500, Poland

  • Tbilisi State Medical University and Ingorokva High Medical Technology University Clinic LLC

    Tbilisi, 144, Georgia

  • Unison Clinical Trials

    Sherman Oaks, California, 91403, United States

  • Velocity Clinical Research

    North Hollywood, California, 91606, United States

  • Yuma Clinical Trials, LLC

    Yuma, Arizona, 85364, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.