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Can an amino acid supplement calm childhood eczema?

NCT ID NCT07670676

Symptom relief Sponsor: Codex Labs Corporation Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a supplement containing L-histidine, along with a topical oil or lotion and unscented soap, could improve mild-to-moderate eczema in children. Forty children ages 1 to 12 were split into two groups: one received a powder supplement and the other a gummy supplement, both with the same amount of L-histidine. Researchers measured changes in eczema severity using standard scoring tools. The goal was to see if this combination could ease symptoms like itching, redness, and dryness.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
L-histidine (amino acid) in powder or gummy supplements, plus topical oil or lotion and unscented soap
What this could lead to
If it works, this could point toward a simple, non-drug way to ease eczema symptoms in children.
What could go wrong
This is a small, completed study with only 40 children and no control group. Results may not apply to all kids, and supplements are not a substitute for medical treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

40 people

The number who actually took part.

Started

Dec 2025

Finished

Mar 2026

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

1 year to 12 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Sex: female and male; * Age : from 1 to 12 years old; * Phototype: I to IV; * Type: Caucasian; * Child having mild to moderate eczema and atopic dermatitis (including but not limited to flakiness, irritation, itching and dryness); * No change in hygiene, cosmetics - except for the product(s) under study - during the entire study duration; * Subjects/Subjects parent's agreeing not to change lifestyle habits of child during the study duration. * Healthy child; * Child whose at least one parent/legal guardian has given freely and expressly her/his informed consent; * Child whose at least one parent/legal guardian is willing to adhere to the protocol and study procedures; * Child with Polish citizenship. Exclusion Criteria: * Cutaneous pathology on the study zone (other than atopic dermatitis); * Use of topical or systemic treatment during the previous weeks liable to interfere with the assessment of the cutaneous acceptability/efficacy of the study product (the subjects are allowed to use their topical corticosteroids during the study if needed; the information about the treatment and the number of applications must be noted in the daily log); * Child having undergone a surgery under general anesthesia within the previous month; * Excessive exposure to sunlight or UV-rays within the previous month; * Child enrolled in another clinical trial during the study period.

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Conditions

The condition(s) this trial relates to.

atopic eczema Eczema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Atopic dermatitis (eczema)

Contacts and locations

Locations

  • Eurofins Dermscan Poland

    Gdansk, Poland

More trials for these conditions

Other studies related to the condition(s) this trial covers.