Breath test breakthrough: scientists read RNA in exhaled air
NCT ID NCT07324252
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This pilot study tested whether it is possible to collect and analyze small RNA molecules from a person's breath. Researchers took breath samples from 25 volunteers (healthy people and a few with lung disease) at rest and after intense exercise. They successfully extracted and sequenced the RNA, showing that breath can be used to study changes in the body without needles or invasive procedures.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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25 people
The number who actually took part.
- Started
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Jan 2025
- Finished
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Dec 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
healthy volouteers, amateur athletes (runners) and lung cancer patients with stage IIIb or VI disease
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * ability to perform CPET * ability to perform spirometry Exclusion Criteria: * lack of informed consent * absolute contradictions to CPET or spirometry
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Department of Respiratory Physiopathology, Medical University of Bialystok
Bialystok, Podlaskie Voivodeship, 15-540, Poland
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