Can a COPD flare stun the heart? study watches for hidden strain
NCT ID NCT06597331
First seen Sep 17, 2026 · Last updated Sep 18, 2026 · Updated 1 time
Summary
Researchers at Sahlgrenska University Hospital in Sweden are observing 200 adults hospitalized for a severe COPD flare-up to see how often the condition triggers a temporary heart muscle weakness called Takotsubo stunning. They will use echocardiograms to check heart function at admission and again on day 1 and day 30, and track signs of acute heart failure and other heart problems during the hospital stay. The study compares patients who develop heart stunning with those who do not, aiming to understand whether this complication worsens outcomes.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If the link holds, doctors could monitor COPD flare-ups for hidden heart strain and treat it earlier, possibly preventing heart failure during hospitalization.
- What could go wrong
- This observational study cannot prove cause and effect, and it takes place at one hospital in Sweden, so the findings may not apply broadly. The heart imaging and follow-up may also miss subtle cases.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 200 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2024
- Expected to finish
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Sep 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adult patients admitted to hospital ward for AE-COPD within 72 hours
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adult patients (≥ 18 years old) admitted to hospital ward for AE-COPD * Inclusion within 72 hours of admission, * Written informed consent Exclusion Criteria: * Prior acute myocardial infarction or known pre-existing persistent regional wall motion abnormality or left ventricular dysfunction (left ventricular ejection fraction \[LVEF\] \<50%) * Expected inability to comply with the protocol (e.g. dementia)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Department of Emergency Medicine and Geriatrics, Sahlgrenska University Hospital/S
RECRUITINGGothenburg, Region Västra Götaland, 41345, Sweden
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