Please sign in to follow a disease.
Detailed lung scans could map COPD damage more precisely
NCT ID NCT07809399
First seen Sep 09, 2026 · Last updated Sep 10, 2026 · Updated 1 time
Summary
Researchers are studying whether volumetric high-resolution CT scans can give a detailed picture of lung damage in people with stable chronic obstructive pulmonary disease (COPD). The study enrolls 75 patients with COPD confirmed by breathing tests. Participants receive both a specialized CT scan and standard lung function tests. The goal is to see how well the CT measurements of emphysema, air trapping, and airway wall thickness match up with the severity of disease measured by breathing tests.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Volumetric high-resolution computed tomography (HRCT) of the chest
- What this could lead to
- If the imaging measures prove reliable, doctors could use them to stage COPD more precisely and tailor treatment to each patient's specific lung changes.
- What could go wrong
- This is a small observational study at one center, so the findings may not apply broadly. CT scans also expose patients to radiation, and the imaging measures may not correlate well with symptoms or lung function.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
75 people
The number who actually took part.
- Started
-
Apr 2025
- Finished
-
Aug 2026
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients attending the smoking clinic and chest disease general clinic at Mansoura University Hospital who have stable COPD confirmed by pulmonary function testing.
- Ages
-
18 years and older
- Sex
-
Anyone
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria:Patients with stable chronic obstructive pulmonary disease (COPD) Diagnosed according to GOLD criteria (post-bronchodilator FEV1/FVC \< 0.70) \- Exclusion Criteria: 1. Patient in exacerbation defined as change in the patient's baseline dyspnea, cough, and/or sputum beyond normal day-to-day variations within 14 days . (Ko, Fanny W., et al 2016) 2. Connective tissue disease . 3. Previously diagnosed Interstitial lung disease 4. Contraindication to PFT According to ATS (Stanojevic S., et al 2021) * Recent Myocardial Infarction Within 1 week * Blood Pressure Instability Severe hypertension or systemic hypotension * Arrhythmias Significant, uncontrolled atrial or ventricular arrhythmias * Decompensated heart failure * Pulmonary Circulation Issues: Uncontrolled pulmonary hypertension, acute cor pulmonale, or clinically unstable pulmonary embolism * History of Syncope Loss of consciousness related to coughing or forced expiration * Cerebral Aneurysm * Recent Brain Surgery: Within 4 weeks * Concussion: Recent concussion with prolonged symptoms * Eye Surgery: Recent eye surgery within 1 week * Pneumothorax: Active or untreated pneumothorax Recent Thoracic Surgery: Within 4 weeks Recent Abdominal Surgery: Within 4 weeks Late-Term Pregnancy 5. Contraindicatins of 6MWT according to ATS : Absolute contraindications * Unstable Angina Experienced during the previous 1 month. * Recent Myocardial Infarction : Within the previous 1 month. Relative contraindications * Resting Tachycardia: Resting heart rate \> 120{ bpm}. * Severe Uncontrolled Hypertension: * Systolic Blood Pressure \> 180{ mmHg} * Diastolic Blood Pressure \> 100{ mmHg} * Symptomatic/Severe Cardiac Conditions: High-degree atrioventricular (AV) block, hypertrophic cardiomyopathy, or symptomatic severe aortic stenosis.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Airway obstruction are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Mansoura University Hospital (Chest Disease Department)
Al Mansurah, Dakahlia Governorate, 35516, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a COPD flare stun the heart? study watches for hidden strain
- Can better training get doctors to talk about what matters most to dying veterans?
- Can an injected antibody calm inflamed lungs and cut COPD flare-ups?
- Can AI help nurses guide At-Risk seniors to better care and lower costs?
- Fine-Mist inhalers aim to reach deep lungs in COPD
- App alerts COPD patients when their inhalers may be out of date