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Can mushroom extracts soothe skin during breast radiation?

NCT ID NCT07755553

Symptom relief Sponsor: Hifas da Terra S.L. Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 10, 2026 · Last updated Aug 11, 2026 · Updated 1 time

Summary

This trial tests whether a cream made with mushroom extracts can help protect the skin of women undergoing radiation therapy for breast cancer. Participants use the cream or a standard moisturizer on the treated breast twice daily, starting before radiation and continuing for a month after. Researchers measure skin moisture, redness, and comfort to see if the mushroom cream offers better skin support.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
A topical cosmetic cream containing extracts of Cordyceps sinensis, Ganoderma lucidum, and Hericium erinaceus mushrooms
What this could lead to
If it works, this cream could offer a natural way to keep skin healthier and more comfortable during breast radiotherapy.
What could go wrong
This is a small early-stage trial, and the cream is cosmetic, not a medicine, so any benefit may be modest and not guaranteed.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

50 people

The number who actually took part.

Started

Nov 2024

Finished

Oct 2025

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Female sex. * Age 18 to 75 years. * Scheduled to begin breast radiotherapy following breast-conserving surgery. Exclusion Criteria: * Contraindication to radiotherapy. * History of allergic reactions to any component of the assigned cosmetic product. * Use of topical medications or creams on the product application area during the 7 days before starting the assigned cosmetic product. * Hypersensitivity or sensitivity in the area scheduled for irradiation. * Any disease or disorder that, in the investigator's opinion, could interfere with the evaluation of safety or efficacy. * Chronic or currently active skin disease that, in the investigator's opinion, could adversely affect skin condition following radiotherapy. * History of organ removal or organ transplantation. * Immunodeficiency. * Progressive febrile condition. * Use of topical or systemic treatments that could interfere with evaluation of the assigned cosmetic product.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm Erythema radiodermatitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Breast cancer Radiation dermatitis

Contacts and locations

Locations

  • Hospital Universitario de San Juan de Alicante

    Sant Joan d'Alacant, Alicante, 03550, Spain

More trials for these conditions

Other studies related to the condition(s) this trial covers.