Scientists investigate protein link in skin diseases
NCT ID NCT01538342
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at skin samples from 170 people with psoriasis, atopic dermatitis (eczema), or healthy skin to understand how a protein called Lyn is involved in inflammation. Researchers measured Lyn activity and related enzymes in both affected and unaffected skin. The goal was to see if changes in Lyn are specific to psoriasis or common to other inflammatory skin conditions.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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170 people
The number who actually took part.
- Started
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Jul 2012
- Finished
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Jul 2016
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Psoriasis arms: * Plaque psoriasis and erythrodermic more than 10% of body surface area. * Pustular psoriasis of at least 1% of body surface. * Atopic dermatitis arm:Patients with atopic dermatitis has been identified and inflammatory lesions on the skin. * Healthy arm:People not suffering from any skin disease Exclusion Criteria: * Systemic treatment of psoriasis for at least 4 weeks and / or local treatment for at least 2 weeks at the time of study entry. * Patient with significant infection and / or immunocompromised.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Assistance Publique - Hôpitaux de Marseille
Marseille, 13 005, France
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University Hospital of Nice
Nice, 06000, France
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University Hospital of Toulouse
Toulouse, 31059, France
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Other studies related to the condition(s) this trial covers.
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